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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF280B
Full Name:
Zinc finger protein 280B
Alias:
5'OY11.1; suppressor of hairy wing homolog 2; ZNF279; ZNF632
Type:
Mass (Da):
61525
Number AA:
543
UniProt ID:
Q86YH2
International Prot ID:
IPI00329383
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T65
S
N
I
L
N
R
V
T
P
G
S
W
S
R
R
Site 2
S68
L
N
R
V
T
P
G
S
W
S
R
R
K
K
Y
Site 3
S70
R
V
T
P
G
S
W
S
R
R
K
K
Y
D
H
Site 4
Y75
S
W
S
R
R
K
K
Y
D
H
L
R
K
D
T
Site 5
T82
Y
D
H
L
R
K
D
T
A
R
K
L
Q
P
K
Site 6
S90
A
R
K
L
Q
P
K
S
H
E
T
V
T
S
E
Site 7
S96
K
S
H
E
T
V
T
S
E
A
V
T
V
L
P
Site 8
S105
A
V
T
V
L
P
A
S
Q
L
E
S
R
S
T
Site 9
S109
L
P
A
S
Q
L
E
S
R
S
T
D
S
P
I
Site 10
S111
A
S
Q
L
E
S
R
S
T
D
S
P
I
I
I
Site 11
T112
S
Q
L
E
S
R
S
T
D
S
P
I
I
I
E
Site 12
S114
L
E
S
R
S
T
D
S
P
I
I
I
E
P
L
Site 13
S122
P
I
I
I
E
P
L
S
K
P
D
Y
R
N
S
Site 14
Y126
E
P
L
S
K
P
D
Y
R
N
S
S
P
Q
V
Site 15
S129
S
K
P
D
Y
R
N
S
S
P
Q
V
V
P
N
Site 16
S130
K
P
D
Y
R
N
S
S
P
Q
V
V
P
N
N
Site 17
S138
P
Q
V
V
P
N
N
S
S
E
L
P
S
P
L
Site 18
S139
Q
V
V
P
N
N
S
S
E
L
P
S
P
L
I
Site 19
S143
N
N
S
S
E
L
P
S
P
L
I
T
F
T
D
Site 20
T147
E
L
P
S
P
L
I
T
F
T
D
S
L
H
H
Site 21
T149
P
S
P
L
I
T
F
T
D
S
L
H
H
P
V
Site 22
S157
D
S
L
H
H
P
V
S
T
A
L
S
V
G
G
Site 23
S161
H
P
V
S
T
A
L
S
V
G
G
I
N
E
S
Site 24
S168
S
V
G
G
I
N
E
S
P
R
V
S
K
Q
L
Site 25
S172
I
N
E
S
P
R
V
S
K
Q
L
S
T
F
E
Site 26
S176
P
R
V
S
K
Q
L
S
T
F
E
V
N
S
I
Site 27
T177
R
V
S
K
Q
L
S
T
F
E
V
N
S
I
N
Site 28
S182
L
S
T
F
E
V
N
S
I
N
P
K
R
A
K
Site 29
S199
D
G
I
I
E
G
N
S
S
A
S
F
P
S
D
Site 30
S200
G
I
I
E
G
N
S
S
A
S
F
P
S
D
T
Site 31
S202
I
E
G
N
S
S
A
S
F
P
S
D
T
F
H
Site 32
S205
N
S
S
A
S
F
P
S
D
T
F
H
T
M
N
Site 33
T207
S
A
S
F
P
S
D
T
F
H
T
M
N
T
Q
Site 34
T213
D
T
F
H
T
M
N
T
Q
Q
S
T
P
S
N
Site 35
T217
T
M
N
T
Q
Q
S
T
P
S
N
N
V
H
T
Site 36
S219
N
T
Q
Q
S
T
P
S
N
N
V
H
T
S
L
Site 37
S225
P
S
N
N
V
H
T
S
L
S
H
V
Q
N
G
Site 38
S227
N
N
V
H
T
S
L
S
H
V
Q
N
G
A
P
Site 39
T262
R
A
N
E
L
A
K
T
D
I
L
S
L
T
S
Site 40
S266
L
A
K
T
D
I
L
S
L
T
S
Q
N
K
T
Site 41
T268
K
T
D
I
L
S
L
T
S
Q
N
K
T
F
D
Site 42
T273
S
L
T
S
Q
N
K
T
F
D
P
K
K
E
N
Site 43
Y289
I
V
L
L
S
D
F
Y
Y
G
Q
H
K
G
E
Site 44
Y290
V
L
L
S
D
F
Y
Y
G
Q
H
K
G
E
G
Site 45
T303
E
G
Q
P
E
Q
K
T
H
T
T
F
K
C
L
Site 46
T306
P
E
Q
K
T
H
T
T
F
K
C
L
S
C
V
Site 47
T367
C
H
I
E
N
V
H
T
A
Q
E
P
S
T
V
Site 48
T373
H
T
A
Q
E
P
S
T
V
C
K
I
C
E
L
Site 49
S413
Q
V
C
H
Y
R
S
S
V
F
A
D
V
E
T
Site 50
S463
G
K
S
A
H
Q
C
S
K
C
R
L
Q
F
L
Site 51
T471
K
C
R
L
Q
F
L
T
F
K
E
K
M
E
H
Site 52
T502
L
P
P
E
T
K
V
T
I
Q
V
S
L
E
P
Site 53
S506
T
K
V
T
I
Q
V
S
L
E
P
L
Q
P
G
Site 54
T521
S
V
D
V
A
S
I
T
V
S
T
S
D
S
E
Site 55
S523
D
V
A
S
I
T
V
S
T
S
D
S
E
P
S
Site 56
S525
A
S
I
T
V
S
T
S
D
S
E
P
S
L
P
Site 57
S527
I
T
V
S
T
S
D
S
E
P
S
L
P
R
S
Site 58
S530
S
T
S
D
S
E
P
S
L
P
R
S
K
S
K
Site 59
S534
S
E
P
S
L
P
R
S
K
S
K
I
S
K
K
Site 60
S536
P
S
L
P
R
S
K
S
K
I
S
K
K
S
H
Site 61
S539
P
R
S
K
S
K
I
S
K
K
S
H
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation