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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOMER1
Full Name:
Homer protein homolog 1
Alias:
HOME1; Homer 1; HOMER1A; HOMER1B; HOMER-1B; HOMER1C; SYN47; Ves-1
Type:
Adaptor/scaffold
Mass (Da):
40258
Number AA:
354
UniProt ID:
Q86YM7
International Prot ID:
IPI00003566
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0005887
GO:0014069
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007206
GO:0007268
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
K
K
N
W
V
P
T
S
K
H
A
V
T
V
S
Site 2
T33
P
T
S
K
H
A
V
T
V
S
Y
F
Y
D
S
Site 3
S35
S
K
H
A
V
T
V
S
Y
F
Y
D
S
T
R
Site 4
Y36
K
H
A
V
T
V
S
Y
F
Y
D
S
T
R
N
Site 5
Y45
Y
D
S
T
R
N
V
Y
R
I
I
S
L
D
G
Site 6
S49
R
N
V
Y
R
I
I
S
L
D
G
S
K
A
I
Site 7
T66
S
T
I
T
P
N
M
T
F
T
K
T
S
Q
K
Site 8
T84
W
A
D
S
R
A
N
T
V
Y
G
L
G
F
S
Site 9
Y86
D
S
R
A
N
T
V
Y
G
L
G
F
S
S
E
Site 10
S91
T
V
Y
G
L
G
F
S
S
E
H
H
L
S
K
Site 11
S97
F
S
S
E
H
H
L
S
K
F
A
E
K
F
Q
Site 12
S117
A
R
L
A
K
E
K
S
Q
E
K
M
E
L
T
Site 13
T124
S
Q
E
K
M
E
L
T
S
T
P
S
Q
E
S
Site 14
T126
E
K
M
E
L
T
S
T
P
S
Q
E
S
A
G
Site 15
S128
M
E
L
T
S
T
P
S
Q
E
S
A
G
G
D
Site 16
S138
S
A
G
G
D
L
Q
S
P
L
T
P
E
S
I
Site 17
T141
G
D
L
Q
S
P
L
T
P
E
S
I
N
G
T
Site 18
S144
Q
S
P
L
T
P
E
S
I
N
G
T
D
D
E
Site 19
T148
T
P
E
S
I
N
G
T
D
D
E
R
T
P
D
Site 20
T153
N
G
T
D
D
E
R
T
P
D
V
T
Q
N
S
Site 21
T157
D
E
R
T
P
D
V
T
Q
N
S
E
P
R
A
Site 22
S160
T
P
D
V
T
Q
N
S
E
P
R
A
E
P
T
Site 23
T167
S
E
P
R
A
E
P
T
Q
N
A
L
P
F
S
Site 24
S174
T
Q
N
A
L
P
F
S
H
S
S
A
I
S
K
Site 25
S176
N
A
L
P
F
S
H
S
S
A
I
S
K
H
W
Site 26
S177
A
L
P
F
S
H
S
S
A
I
S
K
H
W
E
Site 27
S180
F
S
H
S
S
A
I
S
K
H
W
E
A
E
L
Site 28
T198
K
G
N
N
A
K
L
T
A
A
L
L
E
S
T
Site 29
T230
E
R
L
H
K
R
V
T
E
L
E
C
V
S
S
Site 30
S237
T
E
L
E
C
V
S
S
Q
A
N
A
V
H
T
Site 31
T259
T
I
Q
E
L
E
E
T
L
K
L
K
E
E
E
Site 32
S286
E
L
Q
E
Q
R
D
S
L
T
Q
K
L
Q
E
Site 33
S306
K
D
L
E
G
Q
L
S
D
L
E
Q
R
L
E
Site 34
S315
L
E
Q
R
L
E
K
S
Q
N
E
Q
E
A
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation