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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FLJ21438
Full Name:
RAS protein activator like-3
Alias:
RAS protein activator like 3
Type:
Unknown function
Mass (Da):
111898
Number AA:
1076
UniProt ID:
Q86YV0
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005096
PhosphoSite+
KinaseNET
Biological Process:
GO:0051056
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
D
P
P
S
P
S
R
T
S
Q
T
Site 2
S7
_
M
D
P
P
S
P
S
R
T
S
Q
T
Q
P
Site 3
T9
D
P
P
S
P
S
R
T
S
Q
T
Q
P
T
A
Site 4
S10
P
P
S
P
S
R
T
S
Q
T
Q
P
T
A
T
Site 5
T12
S
P
S
R
T
S
Q
T
Q
P
T
A
T
S
P
Site 6
T17
S
Q
T
Q
P
T
A
T
S
P
L
T
S
Y
R
Site 7
S18
Q
T
Q
P
T
A
T
S
P
L
T
S
Y
R
W
Site 8
T21
P
T
A
T
S
P
L
T
S
Y
R
W
H
T
G
Site 9
S22
T
A
T
S
P
L
T
S
Y
R
W
H
T
G
G
Site 10
Y23
A
T
S
P
L
T
S
Y
R
W
H
T
G
G
G
Site 11
T27
L
T
S
Y
R
W
H
T
G
G
G
G
E
K
A
Site 12
S51
A
G
W
G
R
A
L
S
H
Q
E
P
M
V
S
Site 13
S58
S
H
Q
E
P
M
V
S
T
Q
P
A
P
R
S
Site 14
S65
S
T
Q
P
A
P
R
S
I
F
R
R
V
L
S
Site 15
S72
S
I
F
R
R
V
L
S
A
P
P
K
E
S
R
Site 16
S78
L
S
A
P
P
K
E
S
R
T
S
R
L
R
L
Site 17
T80
A
P
P
K
E
S
R
T
S
R
L
R
L
S
K
Site 18
S81
P
P
K
E
S
R
T
S
R
L
R
L
S
K
A
Site 19
S86
R
T
S
R
L
R
L
S
K
A
L
W
G
R
H
Site 20
T121
E
P
E
L
E
P
P
T
P
Q
I
P
E
A
P
Site 21
T129
P
Q
I
P
E
A
P
T
P
N
V
P
V
W
D
Site 22
S164
P
R
R
P
R
V
G
S
A
S
S
E
G
S
I
Site 23
S166
R
P
R
V
G
S
A
S
S
E
G
S
I
H
V
Site 24
S167
P
R
V
G
S
A
S
S
E
G
S
I
H
V
A
Site 25
S170
G
S
A
S
S
E
G
S
I
H
V
A
M
G
N
Site 26
T188
P
D
R
M
P
G
K
T
E
P
E
T
A
G
P
Site 27
T192
P
G
K
T
E
P
E
T
A
G
P
N
Q
V
H
Site 28
S224
E
P
R
D
G
P
P
S
A
L
G
S
R
E
S
Site 29
S228
G
P
P
S
A
L
G
S
R
E
S
L
A
T
L
Site 30
S231
S
A
L
G
S
R
E
S
L
A
T
L
S
E
L
Site 31
T234
G
S
R
E
S
L
A
T
L
S
E
L
D
L
G
Site 32
S236
R
E
S
L
A
T
L
S
E
L
D
L
G
A
E
Site 33
S254
R
I
W
P
L
H
P
S
L
L
G
E
P
H
C
Site 34
S274
T
G
G
S
R
C
F
S
C
R
S
A
A
E
R
Site 35
S277
S
R
C
F
S
C
R
S
A
A
E
R
D
R
W
Site 36
T295
L
R
R
Q
F
Q
P
T
Q
D
N
V
E
R
E
Site 37
T340
D
G
A
L
L
A
R
T
A
P
R
A
G
P
G
Site 38
S367
L
P
P
A
R
R
L
S
L
R
L
R
G
L
G
Site 39
S429
R
R
L
R
V
L
P
S
E
R
Y
K
E
L
A
Site 40
Y512
A
T
K
A
I
D
E
Y
M
K
L
V
A
Q
D
Site 41
Y520
M
K
L
V
A
Q
D
Y
L
Q
E
T
L
G
Q
Site 42
S535
V
V
R
R
L
C
A
S
T
E
D
C
E
V
D
Site 43
T536
V
R
R
L
C
A
S
T
E
D
C
E
V
D
P
Site 44
S544
E
D
C
E
V
D
P
S
K
C
P
A
S
E
L
Site 45
S549
D
P
S
K
C
P
A
S
E
L
P
E
H
Q
A
Site 46
S561
H
Q
A
R
L
R
N
S
C
E
E
V
F
E
T
Site 47
S586
E
L
G
I
V
F
S
S
W
R
E
A
C
K
E
Site 48
S596
E
A
C
K
E
R
G
S
E
V
L
G
P
R
L
Site 49
Y660
P
F
G
E
K
E
A
Y
M
G
F
M
N
S
F
Site 50
S666
A
Y
M
G
F
M
N
S
F
L
E
E
H
G
P
Site 51
S692
V
D
V
D
A
A
P
S
G
Y
Q
G
S
G
D
Site 52
T721
I
F
A
E
L
D
Q
T
T
R
D
T
L
E
P
Site 53
T725
L
D
Q
T
T
R
D
T
L
E
P
L
P
T
I
Site 54
T731
D
T
L
E
P
L
P
T
I
L
R
A
I
E
E
Site 55
S760
P
P
A
Q
V
H
S
S
L
S
A
G
E
K
P
Site 56
S762
A
Q
V
H
S
S
L
S
A
G
E
K
P
G
F
Site 57
T779
P
R
D
L
P
K
H
T
P
L
I
S
K
S
Q
Site 58
S783
P
K
H
T
P
L
I
S
K
S
Q
S
L
R
S
Site 59
S785
H
T
P
L
I
S
K
S
Q
S
L
R
S
V
R
Site 60
S787
P
L
I
S
K
S
Q
S
L
R
S
V
R
R
S
Site 61
S790
S
K
S
Q
S
L
R
S
V
R
R
S
E
S
W
Site 62
S794
S
L
R
S
V
R
R
S
E
S
W
A
R
P
R
Site 63
S796
R
S
V
R
R
S
E
S
W
A
R
P
R
P
D
Site 64
T817
R
P
R
P
V
Q
R
T
Q
S
V
P
V
R
R
Site 65
S819
R
P
V
Q
R
T
Q
S
V
P
V
R
R
P
A
Site 66
S831
R
P
A
R
R
R
Q
S
A
G
P
W
P
R
P
Site 67
S841
P
W
P
R
P
K
G
S
L
S
M
G
P
A
P
Site 68
S843
P
R
P
K
G
S
L
S
M
G
P
A
P
R
A
Site 69
T854
A
P
R
A
R
P
W
T
R
D
S
A
S
L
P
Site 70
S857
A
R
P
W
T
R
D
S
A
S
L
P
R
K
P
Site 71
S859
P
W
T
R
D
S
A
S
L
P
R
K
P
S
V
Site 72
S865
A
S
L
P
R
K
P
S
V
P
W
Q
R
Q
M
Site 73
T884
D
R
N
Q
A
L
G
T
H
R
P
V
N
K
L
Site 74
S909
R
E
E
Q
K
V
L
S
R
L
V
E
S
L
S
Site 75
S916
S
R
L
V
E
S
L
S
T
Q
I
R
A
L
T
Site 76
T917
R
L
V
E
S
L
S
T
Q
I
R
A
L
T
E
Site 77
T923
S
T
Q
I
R
A
L
T
E
Q
Q
E
Q
L
R
Site 78
S938
G
Q
L
Q
D
L
D
S
R
L
R
A
G
S
S
Site 79
S944
D
S
R
L
R
A
G
S
S
E
F
D
S
E
H
Site 80
S945
S
R
L
R
A
G
S
S
E
F
D
S
E
H
N
Site 81
S949
A
G
S
S
E
F
D
S
E
H
N
L
T
S
N
Site 82
T954
F
D
S
E
H
N
L
T
S
N
E
G
H
S
L
Site 83
T974
R
L
N
E
M
E
R
T
Q
A
Q
L
R
D
A
Site 84
S984
Q
L
R
D
A
V
Q
S
L
Q
L
S
P
R
T
Site 85
S988
A
V
Q
S
L
Q
L
S
P
R
T
R
G
S
W
Site 86
S994
L
S
P
R
T
R
G
S
W
S
Q
P
Q
P
L
Site 87
S996
P
R
T
R
G
S
W
S
Q
P
Q
P
L
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation