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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HRNR
Full Name:
Hornerin
Alias:
HORN; intermediate filament-associated; S100A16; S100A18
Type:
Cytoskeletal protein
Mass (Da):
282390
Number AA:
2850
UniProt ID:
Q86YZ3
International Prot ID:
IPI00398625
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0031424
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
V
I
D
V
F
Y
Q
Y
A
T
Q
H
G
E
Y
Site 2
T27
T
Q
H
G
E
Y
D
T
L
N
K
A
E
L
K
Site 3
T53
K
N
P
N
D
P
D
T
V
D
I
I
L
Q
S
Site 4
S60
T
V
D
I
I
L
Q
S
L
D
R
D
H
N
K
Site 5
Y93
N
K
I
I
G
K
D
Y
C
Q
V
S
G
S
K
Site 6
S97
G
K
D
Y
C
Q
V
S
G
S
K
L
R
D
D
Site 7
S99
D
Y
C
Q
V
S
G
S
K
L
R
D
D
T
H
Site 8
T105
G
S
K
L
R
D
D
T
H
Q
H
Q
E
E
Q
Site 9
T115
H
Q
E
E
Q
E
E
T
E
K
E
E
N
K
R
Site 10
S125
E
E
N
K
R
Q
E
S
S
F
S
H
S
S
W
Site 11
S126
E
N
K
R
Q
E
S
S
F
S
H
S
S
W
S
Site 12
S128
K
R
Q
E
S
S
F
S
H
S
S
W
S
A
G
Site 13
S130
Q
E
S
S
F
S
H
S
S
W
S
A
G
E
N
Site 14
S131
E
S
S
F
S
H
S
S
W
S
A
G
E
N
D
Site 15
S133
S
F
S
H
S
S
W
S
A
G
E
N
D
S
Y
Site 16
S139
W
S
A
G
E
N
D
S
Y
S
R
N
V
R
G
Site 17
Y140
S
A
G
E
N
D
S
Y
S
R
N
V
R
G
S
Site 18
S141
A
G
E
N
D
S
Y
S
R
N
V
R
G
S
L
Site 19
S147
Y
S
R
N
V
R
G
S
L
K
P
G
T
E
S
Site 20
T152
R
G
S
L
K
P
G
T
E
S
I
S
R
R
L
Site 21
S154
S
L
K
P
G
T
E
S
I
S
R
R
L
S
F
Site 22
S156
K
P
G
T
E
S
I
S
R
R
L
S
F
Q
R
Site 23
S160
E
S
I
S
R
R
L
S
F
Q
R
D
F
S
G
Site 24
S166
L
S
F
Q
R
D
F
S
G
Q
H
N
S
Y
S
Site 25
S171
D
F
S
G
Q
H
N
S
Y
S
G
Q
S
S
S
Site 26
Y172
F
S
G
Q
H
N
S
Y
S
G
Q
S
S
S
Y
Site 27
S173
S
G
Q
H
N
S
Y
S
G
Q
S
S
S
Y
G
Site 28
S177
N
S
Y
S
G
Q
S
S
S
Y
G
E
Q
N
S
Site 29
S178
S
Y
S
G
Q
S
S
S
Y
G
E
Q
N
S
D
Site 30
S184
S
S
Y
G
E
Q
N
S
D
S
H
Q
S
S
G
Site 31
S186
Y
G
E
Q
N
S
D
S
H
Q
S
S
G
R
G
Site 32
S190
N
S
D
S
H
Q
S
S
G
R
G
Q
C
G
S
Site 33
S197
S
G
R
G
Q
C
G
S
G
S
G
Q
S
P
N
Site 34
S199
R
G
Q
C
G
S
G
S
G
Q
S
P
N
Y
G
Site 35
S202
C
G
S
G
S
G
Q
S
P
N
Y
G
Q
H
G
Site 36
Y205
G
S
G
Q
S
P
N
Y
G
Q
H
G
S
G
S
Site 37
S210
P
N
Y
G
Q
H
G
S
G
S
G
Q
S
S
S
Site 38
S212
Y
G
Q
H
G
S
G
S
G
Q
S
S
S
N
D
Site 39
S215
H
G
S
G
S
G
Q
S
S
S
N
D
T
H
G
Site 40
S216
G
S
G
S
G
Q
S
S
S
N
D
T
H
G
S
Site 41
S217
S
G
S
G
Q
S
S
S
N
D
T
H
G
S
G
Site 42
T220
G
Q
S
S
S
N
D
T
H
G
S
G
S
G
Q
Site 43
S223
S
S
N
D
T
H
G
S
G
S
G
Q
S
S
G
Site 44
S225
N
D
T
H
G
S
G
S
G
Q
S
S
G
F
S
Site 45
S228
H
G
S
G
S
G
Q
S
S
G
F
S
Q
H
K
Site 46
S229
G
S
G
S
G
Q
S
S
G
F
S
Q
H
K
S
Site 47
S232
S
G
Q
S
S
G
F
S
Q
H
K
S
S
S
G
Site 48
S236
S
G
F
S
Q
H
K
S
S
S
G
Q
S
S
G
Site 49
S237
G
F
S
Q
H
K
S
S
S
G
Q
S
S
G
Y
Site 50
S238
F
S
Q
H
K
S
S
S
G
Q
S
S
G
Y
S
Site 51
S241
H
K
S
S
S
G
Q
S
S
G
Y
S
Q
H
G
Site 52
S242
K
S
S
S
G
Q
S
S
G
Y
S
Q
H
G
S
Site 53
Y244
S
S
G
Q
S
S
G
Y
S
Q
H
G
S
G
S
Site 54
S245
S
G
Q
S
S
G
Y
S
Q
H
G
S
G
S
G
Site 55
S249
S
G
Y
S
Q
H
G
S
G
S
G
H
S
S
G
Site 56
S251
Y
S
Q
H
G
S
G
S
G
H
S
S
G
Y
G
Site 57
S254
H
G
S
G
S
G
H
S
S
G
Y
G
Q
H
G
Site 58
S255
G
S
G
S
G
H
S
S
G
Y
G
Q
H
G
S
Site 59
Y257
G
S
G
H
S
S
G
Y
G
Q
H
G
S
R
S
Site 60
S262
S
G
Y
G
Q
H
G
S
R
S
G
Q
S
S
R
Site 61
S264
Y
G
Q
H
G
S
R
S
G
Q
S
S
R
G
E
Site 62
S267
H
G
S
R
S
G
Q
S
S
R
G
E
R
H
R
Site 63
S268
G
S
R
S
G
Q
S
S
R
G
E
R
H
R
S
Site 64
S275
S
R
G
E
R
H
R
S
S
S
G
S
S
S
S
Site 65
S276
R
G
E
R
H
R
S
S
S
G
S
S
S
S
Y
Site 66
S277
G
E
R
H
R
S
S
S
G
S
S
S
S
Y
G
Site 67
S279
R
H
R
S
S
S
G
S
S
S
S
Y
G
Q
H
Site 68
S280
H
R
S
S
S
G
S
S
S
S
Y
G
Q
H
G
Site 69
S281
R
S
S
S
G
S
S
S
S
Y
G
Q
H
G
S
Site 70
S282
S
S
S
G
S
S
S
S
Y
G
Q
H
G
S
G
Site 71
Y283
S
S
G
S
S
S
S
Y
G
Q
H
G
S
G
S
Site 72
S288
S
S
Y
G
Q
H
G
S
G
S
R
Q
S
L
G
Site 73
S290
Y
G
Q
H
G
S
G
S
R
Q
S
L
G
H
G
Site 74
S293
H
G
S
G
S
R
Q
S
L
G
H
G
R
Q
G
Site 75
S301
L
G
H
G
R
Q
G
S
G
S
R
Q
S
P
S
Site 76
S303
H
G
R
Q
G
S
G
S
R
Q
S
P
S
H
V
Site 77
S306
Q
G
S
G
S
R
Q
S
P
S
H
V
R
H
G
Site 78
S308
S
G
S
R
Q
S
P
S
H
V
R
H
G
S
G
Site 79
S314
P
S
H
V
R
H
G
S
G
S
G
H
S
S
S
Site 80
S316
H
V
R
H
G
S
G
S
G
H
S
S
S
H
G
Site 81
S319
H
G
S
G
S
G
H
S
S
S
H
G
Q
H
G
Site 82
S320
G
S
G
S
G
H
S
S
S
H
G
Q
H
G
S
Site 83
S321
S
G
S
G
H
S
S
S
H
G
Q
H
G
S
G
Site 84
S327
S
S
H
G
Q
H
G
S
G
S
S
Y
S
Y
S
Site 85
S329
H
G
Q
H
G
S
G
S
S
Y
S
Y
S
R
G
Site 86
S330
G
Q
H
G
S
G
S
S
Y
S
Y
S
R
G
H
Site 87
Y331
Q
H
G
S
G
S
S
Y
S
Y
S
R
G
H
Y
Site 88
S332
H
G
S
G
S
S
Y
S
Y
S
R
G
H
Y
E
Site 89
Y333
G
S
G
S
S
Y
S
Y
S
R
G
H
Y
E
S
Site 90
S334
S
G
S
S
Y
S
Y
S
R
G
H
Y
E
S
G
Site 91
Y338
Y
S
Y
S
R
G
H
Y
E
S
G
S
G
Q
T
Site 92
S340
Y
S
R
G
H
Y
E
S
G
S
G
Q
T
S
G
Site 93
S342
R
G
H
Y
E
S
G
S
G
Q
T
S
G
F
G
Site 94
S346
E
S
G
S
G
Q
T
S
G
F
G
Q
H
E
S
Site 95
S353
S
G
F
G
Q
H
E
S
G
S
G
Q
S
S
G
Site 96
S355
F
G
Q
H
E
S
G
S
G
Q
S
S
G
Y
S
Site 97
S358
H
E
S
G
S
G
Q
S
S
G
Y
S
K
H
G
Site 98
S359
E
S
G
S
G
Q
S
S
G
Y
S
K
H
G
S
Site 99
Y361
G
S
G
Q
S
S
G
Y
S
K
H
G
S
G
S
Site 100
S362
S
G
Q
S
S
G
Y
S
K
H
G
S
G
S
G
Site 101
S366
S
G
Y
S
K
H
G
S
G
S
G
H
S
S
S
Site 102
S368
Y
S
K
H
G
S
G
S
G
H
S
S
S
Q
G
Site 103
S371
H
G
S
G
S
G
H
S
S
S
Q
G
Q
H
G
Site 104
S372
G
S
G
S
G
H
S
S
S
Q
G
Q
H
G
S
Site 105
S373
S
G
S
G
H
S
S
S
Q
G
Q
H
G
S
T
Site 106
S379
S
S
Q
G
Q
H
G
S
T
S
G
Q
A
S
S
Site 107
S381
Q
G
Q
H
G
S
T
S
G
Q
A
S
S
S
G
Site 108
S385
G
S
T
S
G
Q
A
S
S
S
G
Q
H
G
S
Site 109
S386
S
T
S
G
Q
A
S
S
S
G
Q
H
G
S
S
Site 110
S387
T
S
G
Q
A
S
S
S
G
Q
H
G
S
S
S
Site 111
S392
S
S
S
G
Q
H
G
S
S
S
R
Q
S
S
S
Site 112
S393
S
S
G
Q
H
G
S
S
S
R
Q
S
S
S
Y
Site 113
S394
S
G
Q
H
G
S
S
S
R
Q
S
S
S
Y
G
Site 114
S397
H
G
S
S
S
R
Q
S
S
S
Y
G
Q
H
E
Site 115
S398
G
S
S
S
R
Q
S
S
S
Y
G
Q
H
E
S
Site 116
S399
S
S
S
R
Q
S
S
S
Y
G
Q
H
E
S
A
Site 117
Y400
S
S
R
Q
S
S
S
Y
G
Q
H
E
S
A
S
Site 118
S405
S
S
Y
G
Q
H
E
S
A
S
R
H
S
S
G
Site 119
S407
Y
G
Q
H
E
S
A
S
R
H
S
S
G
R
G
Site 120
S410
H
E
S
A
S
R
H
S
S
G
R
G
Q
H
S
Site 121
S411
E
S
A
S
R
H
S
S
G
R
G
Q
H
S
S
Site 122
S417
S
S
G
R
G
Q
H
S
S
G
S
G
Q
S
P
Site 123
S418
S
G
R
G
Q
H
S
S
G
S
G
Q
S
P
G
Site 124
S420
R
G
Q
H
S
S
G
S
G
Q
S
P
G
H
G
Site 125
S423
H
S
S
G
S
G
Q
S
P
G
H
G
Q
R
G
Site 126
S431
P
G
H
G
Q
R
G
S
G
S
G
Q
S
P
S
Site 127
S433
H
G
Q
R
G
S
G
S
G
Q
S
P
S
S
G
Site 128
S436
R
G
S
G
S
G
Q
S
P
S
S
G
Q
H
G
Site 129
S438
S
G
S
G
Q
S
P
S
S
G
Q
H
G
T
G
Site 130
S439
G
S
G
Q
S
P
S
S
G
Q
H
G
T
G
F
Site 131
T444
P
S
S
G
Q
H
G
T
G
F
G
R
S
S
S
Site 132
S449
H
G
T
G
F
G
R
S
S
S
S
G
P
Y
V
Site 133
S450
G
T
G
F
G
R
S
S
S
S
G
P
Y
V
S
Site 134
S451
T
G
F
G
R
S
S
S
S
G
P
Y
V
S
G
Site 135
S452
G
F
G
R
S
S
S
S
G
P
Y
V
S
G
S
Site 136
Y455
R
S
S
S
S
G
P
Y
V
S
G
S
G
Y
S
Site 137
S457
S
S
S
G
P
Y
V
S
G
S
G
Y
S
S
G
Site 138
S459
S
G
P
Y
V
S
G
S
G
Y
S
S
G
F
G
Site 139
Y461
P
Y
V
S
G
S
G
Y
S
S
G
F
G
H
H
Site 140
S463
V
S
G
S
G
Y
S
S
G
F
G
H
H
E
S
Site 141
S470
S
G
F
G
H
H
E
S
S
S
E
H
S
S
G
Site 142
S471
G
F
G
H
H
E
S
S
S
E
H
S
S
G
Y
Site 143
S472
F
G
H
H
E
S
S
S
E
H
S
S
G
Y
T
Site 144
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S
Site 450
S1356
Y
G
R
H
G
A
G
S
G
Q
S
P
S
R
G
Site 451
S1359
H
G
A
G
S
G
Q
S
P
S
R
G
R
H
G
Site 452
S1361
A
G
S
G
Q
S
P
S
R
G
R
H
G
S
G
Site 453
S1367
P
S
R
G
R
H
G
S
G
S
G
H
S
S
S
Site 454
S1369
R
G
R
H
G
S
G
S
G
H
S
S
S
Y
G
Site 455
S1372
H
G
S
G
S
G
H
S
S
S
Y
G
Q
H
G
Site 456
S1373
G
S
G
S
G
H
S
S
S
Y
G
Q
H
G
S
Site 457
S1374
S
G
S
G
H
S
S
S
Y
G
Q
H
G
S
G
Site 458
Y1375
G
S
G
H
S
S
S
Y
G
Q
H
G
S
G
S
Site 459
S1382
Y
G
Q
H
G
S
G
S
G
W
S
S
S
S
G
Site 460
S1385
H
G
S
G
S
G
W
S
S
S
S
G
R
H
G
Site 461
S1386
G
S
G
S
G
W
S
S
S
S
G
R
H
G
S
Site 462
S1387
S
G
S
G
W
S
S
S
S
G
R
H
G
S
G
Site 463
S1388
G
S
G
W
S
S
S
S
G
R
H
G
S
G
S
Site 464
S1398
H
G
S
G
S
G
Q
S
S
G
F
G
H
H
E
Site 465
S1399
G
S
G
S
G
Q
S
S
G
F
G
H
H
E
S
Site 466
S1406
S
G
F
G
H
H
E
S
S
S
W
Q
S
S
G
Site 467
S1407
G
F
G
H
H
E
S
S
S
W
Q
S
S
G
C
Site 468
S1408
F
G
H
H
E
S
S
S
W
Q
S
S
G
C
T
Site 469
S1411
H
E
S
S
S
W
Q
S
S
G
C
T
Q
H
G
Site 470
S1412
E
S
S
S
W
Q
S
S
G
C
T
Q
H
G
S
Site 471
T1415
S
W
Q
S
S
G
C
T
Q
H
G
S
G
S
G
Site 472
S1419
S
G
C
T
Q
H
G
S
G
S
G
H
S
S
S
Site 473
S1421
C
T
Q
H
G
S
G
S
G
H
S
S
S
Y
E
Site 474
S1434
Y
E
Q
H
G
S
R
S
G
Q
S
S
R
G
E
Site 475
S1445
S
R
G
E
R
H
G
S
S
S
G
S
S
S
S
Site 476
S1446
R
G
E
R
H
G
S
S
S
G
S
S
S
S
Y
Site 477
S1447
G
E
R
H
G
S
S
S
G
S
S
S
S
Y
G
Site 478
S1449
R
H
G
S
S
S
G
S
S
S
S
Y
G
Q
H
Site 479
S1488
R
G
R
H
G
S
G
S
G
Q
S
S
S
Y
S
Site 480
S1491
H
G
S
G
S
G
Q
S
S
S
Y
S
P
Y
G
Site 481
S1492
G
S
G
S
G
Q
S
S
S
Y
S
P
Y
G
S
Site 482
S1493
S
G
S
G
Q
S
S
S
Y
S
P
Y
G
S
G
Site 483
Y1494
G
S
G
Q
S
S
S
Y
S
P
Y
G
S
G
S
Site 484
S1495
S
G
Q
S
S
S
Y
S
P
Y
G
S
G
S
G
Site 485
Y1497
Q
S
S
S
Y
S
P
Y
G
S
G
S
G
W
S
Site 486
S1499
S
S
Y
S
P
Y
G
S
G
S
G
W
S
S
S
Site 487
S1501
Y
S
P
Y
G
S
G
S
G
W
S
S
S
R
G
Site 488
S1504
Y
G
S
G
S
G
W
S
S
S
R
G
P
Y
E
Site 489
S1505
G
S
G
S
G
W
S
S
S
R
G
P
Y
E
S
Site 490
Y1510
W
S
S
S
R
G
P
Y
E
S
G
S
S
H
S
Site 491
S1512
S
S
R
G
P
Y
E
S
G
S
S
H
S
S
G
Site 492
S1514
R
G
P
Y
E
S
G
S
S
H
S
S
G
L
G
Site 493
S1515
G
P
Y
E
S
G
S
S
H
S
S
G
L
G
H
Site 494
S1518
E
S
G
S
S
H
S
S
G
L
G
H
R
E
S
Site 495
S1681
S
R
G
E
R
H
G
S
S
S
R
S
S
S
R
Site 496
S1682
R
G
E
R
H
G
S
S
S
R
S
S
S
R
Y
Site 497
S1683
G
E
R
H
G
S
S
S
R
S
S
S
R
Y
G
Site 498
S1685
R
H
G
S
S
S
R
S
S
S
R
Y
G
Q
H
Site 499
S1686
H
G
S
S
S
R
S
S
S
R
Y
G
Q
H
G
Site 500
S1687
G
S
S
S
R
S
S
S
R
Y
G
Q
H
G
S
Site 501
Y1689
S
S
R
S
S
S
R
Y
G
Q
H
G
S
G
S
Site 502
S1694
S
R
Y
G
Q
H
G
S
G
S
R
Q
S
S
G
Site 503
S1707
S
G
H
G
R
Q
G
S
G
S
G
Q
S
P
S
Site 504
S1709
H
G
R
Q
G
S
G
S
G
Q
S
P
S
R
G
Site 505
S1714
S
G
S
G
Q
S
P
S
R
G
R
H
G
S
G
Site 506
S1799
T
F
D
Q
E
G
S
S
T
G
Q
S
S
S
H
Site 507
T1800
F
D
Q
E
G
S
S
T
G
Q
S
S
S
H
G
Site 508
S1803
E
G
S
S
T
G
Q
S
S
S
H
G
Q
H
G
Site 509
S1804
G
S
S
T
G
Q
S
S
S
H
G
Q
H
G
S
Site 510
S1805
S
S
T
G
Q
S
S
S
H
G
Q
H
G
S
G
Site 511
S1811
S
S
H
G
Q
H
G
S
G
S
S
Q
S
S
S
Site 512
S1813
H
G
Q
H
G
S
G
S
S
Q
S
S
S
Y
G
Site 513
S1814
G
Q
H
G
S
G
S
S
Q
S
S
S
Y
G
Q
Site 514
S1816
H
G
S
G
S
S
Q
S
S
S
Y
G
Q
Q
G
Site 515
S1817
G
S
G
S
S
Q
S
S
S
Y
G
Q
Q
G
S
Site 516
S1818
S
G
S
S
Q
S
S
S
Y
G
Q
Q
G
S
G
Site 517
Y1819
G
S
S
Q
S
S
S
Y
G
Q
Q
G
S
G
S
Site 518
S1824
S
S
Y
G
Q
Q
G
S
G
S
G
Q
S
P
S
Site 519
S1877
G
F
G
H
H
E
S
S
S
W
Q
S
S
G
Y
Site 520
S1878
F
G
H
H
E
S
S
S
W
Q
S
S
G
Y
T
Site 521
S1881
H
E
S
S
S
W
Q
S
S
G
Y
T
Q
H
G
Site 522
S1882
E
S
S
S
W
Q
S
S
G
Y
T
Q
H
G
S
Site 523
Y1884
S
S
W
Q
S
S
G
Y
T
Q
H
G
S
G
S
Site 524
T1885
S
W
Q
S
S
G
Y
T
Q
H
G
S
G
S
G
Site 525
S1907
H
G
S
R
S
G
Q
S
S
R
G
E
Q
H
G
Site 526
S1908
G
S
R
S
G
Q
S
S
R
G
E
Q
H
G
S
Site 527
S1915
S
R
G
E
Q
H
G
S
S
S
G
S
S
S
S
Site 528
S1916
R
G
E
Q
H
G
S
S
S
G
S
S
S
S
Y
Site 529
S1917
G
E
Q
H
G
S
S
S
G
S
S
S
S
Y
G
Site 530
S1961
H
G
S
G
S
G
Q
S
S
S
Y
G
P
Y
G
Site 531
S1962
G
S
G
S
G
Q
S
S
S
Y
G
P
Y
G
S
Site 532
S1963
S
G
S
G
Q
S
S
S
Y
G
P
Y
G
S
G
Site 533
Y1964
G
S
G
Q
S
S
S
Y
G
P
Y
G
S
G
S
Site 534
Y1967
Q
S
S
S
Y
G
P
Y
G
S
G
S
G
W
S
Site 535
S1969
S
S
Y
G
P
Y
G
S
G
S
G
W
S
S
S
Site 536
S1971
Y
G
P
Y
G
S
G
S
G
W
S
S
S
R
G
Site 537
T2015
S
S
S
G
H
S
S
T
H
G
Q
H
G
S
A
Site 538
S2021
S
T
H
G
Q
H
G
S
A
S
G
Q
S
S
S
Site 539
S2023
H
G
Q
H
G
S
A
S
G
Q
S
S
S
C
G
Site 540
S2026
H
G
S
A
S
G
Q
S
S
S
C
G
Q
H
G
Site 541
S2027
G
S
A
S
G
Q
S
S
S
C
G
Q
H
G
A
Site 542
S2028
S
A
S
G
Q
S
S
S
C
G
Q
H
G
A
S
Site 543
S2092
G
S
G
S
G
R
S
S
S
S
G
Q
H
G
P
Site 544
S2093
S
G
S
G
R
S
S
S
S
G
Q
H
G
P
G
Site 545
S2094
G
S
G
R
S
S
S
S
G
Q
H
G
P
G
L
Site 546
S2104
H
G
P
G
L
G
E
S
S
G
F
G
H
H
E
Site 547
S2105
G
P
G
L
G
E
S
S
G
F
G
H
H
E
S
Site 548
S2151
S
R
G
E
R
H
G
S
S
S
G
S
S
S
R
Site 549
S2152
R
G
E
R
H
G
S
S
S
G
S
S
S
R
Y
Site 550
S2153
G
E
R
H
G
S
S
S
G
S
S
S
R
Y
G
Site 551
S2155
R
H
G
S
S
S
G
S
S
S
R
Y
G
Q
H
Site 552
S2156
H
G
S
S
S
G
S
S
S
R
Y
G
Q
H
G
Site 553
S2157
G
S
S
S
G
S
S
S
R
Y
G
Q
H
G
S
Site 554
Y2159
S
S
G
S
S
S
R
Y
G
Q
H
G
S
G
S
Site 555
S2192
R
G
R
H
G
S
G
S
G
H
S
S
S
H
G
Site 556
Y2684
R
S
S
S
R
G
P
Y
E
S
R
L
G
H
S
Site 557
S2686
S
S
R
G
P
Y
E
S
R
L
G
H
S
S
V
Site 558
S2692
E
S
R
L
G
H
S
S
V
F
G
Q
H
E
S
Site 559
S2766
Y
G
R
H
G
A
G
S
G
Q
S
L
S
H
G
Site 560
S2769
H
G
A
G
S
G
Q
S
L
S
H
G
R
H
G
Site 561
S2771
A
G
S
G
Q
S
L
S
H
G
R
H
G
S
G
Site 562
S2777
L
S
H
G
R
H
G
S
G
S
G
Q
S
S
S
Site 563
S2779
H
G
R
H
G
S
G
S
G
Q
S
S
S
Y
G
Site 564
S2782
H
G
S
G
S
G
Q
S
S
S
Y
G
Q
H
G
Site 565
S2783
G
S
G
S
G
Q
S
S
S
Y
G
Q
H
G
S
Site 566
S2784
S
G
S
G
Q
S
S
S
Y
G
Q
H
G
S
G
Site 567
Y2785
G
S
G
Q
S
S
S
Y
G
Q
H
G
S
G
S
Site 568
S2790
S
S
Y
G
Q
H
G
S
G
S
G
Q
S
S
G
Site 569
S2792
Y
G
Q
H
G
S
G
S
G
Q
S
S
G
Y
S
Site 570
S2795
H
G
S
G
S
G
Q
S
S
G
Y
S
Q
H
G
Site 571
S2796
G
S
G
S
G
Q
S
S
G
Y
S
Q
H
G
S
Site 572
S2803
S
G
Y
S
Q
H
G
S
G
S
G
Q
D
G
Y
Site 573
S2805
Y
S
Q
H
G
S
G
S
G
Q
D
G
Y
S
Y
Site 574
Y2810
S
G
S
G
Q
D
G
Y
S
Y
C
K
G
G
S
Site 575
S2811
G
S
G
Q
D
G
Y
S
Y
C
K
G
G
S
N
Site 576
Y2812
S
G
Q
D
G
Y
S
Y
C
K
G
G
S
N
H
Site 577
S2817
Y
S
Y
C
K
G
G
S
N
H
D
G
G
S
S
Site 578
S2823
G
S
N
H
D
G
G
S
S
G
S
Y
F
L
S
Site 579
S2824
S
N
H
D
G
G
S
S
G
S
Y
F
L
S
F
Site 580
S2826
H
D
G
G
S
S
G
S
Y
F
L
S
F
P
S
Site 581
Y2827
D
G
G
S
S
G
S
Y
F
L
S
F
P
S
S
Site 582
S2830
S
S
G
S
Y
F
L
S
F
P
S
S
T
S
P
Site 583
S2833
S
Y
F
L
S
F
P
S
S
T
S
P
Y
E
Y
Site 584
S2834
Y
F
L
S
F
P
S
S
T
S
P
Y
E
Y
V
Site 585
S2836
L
S
F
P
S
S
T
S
P
Y
E
Y
V
Q
E
Site 586
Y2838
F
P
S
S
T
S
P
Y
E
Y
V
Q
E
Q
R
Site 587
Y2840
S
S
T
S
P
Y
E
Y
V
Q
E
Q
R
C
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation