KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RUNDC2B
Full Name:
RUN domain-containing protein 2B
Alias:
RUN domain containing 2B; RUN2B
Type:
Unknown function
Mass (Da):
27220
Number AA:
249
UniProt ID:
Q8IUI4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
D
E
E
R
S
S
M
L
P
T
M
A
A
Site 2
T11
E
R
S
S
M
L
P
T
M
A
A
G
P
N
S
Site 3
T39
G
Q
S
K
F
A
P
T
V
S
D
L
L
K
E
Site 4
S41
S
K
F
A
P
T
V
S
D
L
L
K
E
S
T
Site 5
T48
S
D
L
L
K
E
S
T
Q
N
V
T
L
L
K
Site 6
S63
E
S
T
Q
G
V
S
S
V
F
R
E
I
T
A
Site 7
S91
T
D
P
L
P
V
V
S
R
N
V
S
A
D
A
Site 8
S95
P
V
V
S
R
N
V
S
A
D
A
K
C
K
K
Site 9
T111
R
K
K
K
K
Q
V
T
N
I
I
S
F
D
D
Site 10
S115
K
Q
V
T
N
I
I
S
F
D
D
E
E
D
E
Site 11
T132
S
G
D
M
F
K
K
T
P
G
A
G
E
S
S
Site 12
S138
K
T
P
G
A
G
E
S
S
E
D
N
S
D
H
Site 13
S139
T
P
G
A
G
E
S
S
E
D
N
S
D
H
S
Site 14
S143
G
E
S
S
E
D
N
S
D
H
S
S
V
N
I
Site 15
S146
S
E
D
N
S
D
H
S
S
V
N
I
M
S
A
Site 16
S147
E
D
N
S
D
H
S
S
V
N
I
M
S
A
F
Site 17
S152
H
S
S
V
N
I
M
S
A
F
E
S
P
F
G
Site 18
S156
N
I
M
S
A
F
E
S
P
F
G
P
N
S
N
Site 19
S162
E
S
P
F
G
P
N
S
N
G
S
Q
S
S
N
Site 20
S165
F
G
P
N
S
N
G
S
Q
S
S
N
S
W
K
Site 21
S167
P
N
S
N
G
S
Q
S
S
N
S
W
K
I
D
Site 22
S168
N
S
N
G
S
Q
S
S
N
S
W
K
I
D
S
Site 23
S175
S
N
S
W
K
I
D
S
L
S
L
N
R
E
F
Site 24
S177
S
W
K
I
D
S
L
S
L
N
R
E
F
G
Y
Site 25
S191
Y
Q
K
L
D
V
K
S
I
D
D
E
D
V
D
Site 26
Y205
D
E
N
E
D
D
V
Y
G
N
S
S
G
R
K
Site 27
S209
D
D
V
Y
G
N
S
S
G
R
K
H
R
G
H
Site 28
S217
G
R
K
H
R
G
H
S
E
S
P
E
K
N
G
Site 29
S219
K
H
R
G
H
S
E
S
P
E
K
N
G
A
H
Site 30
S240
V
Q
W
H
D
L
G
S
L
Q
P
L
P
P
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation