KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CRLF3
Full Name:
Cytokine receptor-like factor 3
Alias:
Cytokine receptor-like molecule 9;Cytokine receptor-related protein 4;Type I cytokine receptor-like factor p48
Type:
Mass (Da):
49766
Number AA:
442
UniProt ID:
Q8IUI8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
E
N
V
E
A
A
Q
S
Y
R
R
E
L
G
H
Site 2
Y26
N
V
E
A
A
Q
S
Y
R
R
E
L
G
H
R
Site 3
S47
A
R
R
Q
I
K
E
S
A
S
Q
T
R
D
V
Site 4
S49
R
Q
I
K
E
S
A
S
Q
T
R
D
V
L
K
Site 5
T51
I
K
E
S
A
S
Q
T
R
D
V
L
K
Q
H
Site 6
T83
T
L
L
Q
E
V
D
T
I
E
Q
E
T
I
K
Site 7
S130
E
E
N
E
K
L
W
S
F
T
K
K
A
S
H
Site 8
S136
W
S
F
T
K
K
A
S
H
I
Q
L
D
S
L
Site 9
T176
D
H
I
F
K
H
G
T
V
A
S
R
P
P
V
Site 10
S179
F
K
H
G
T
V
A
S
R
P
P
V
Q
I
E
Site 11
Y211
D
D
F
T
A
Q
D
Y
R
L
Q
F
R
K
C
Site 12
T219
R
L
Q
F
R
K
C
T
S
N
H
F
E
D
V
Site 13
Y227
S
N
H
F
E
D
V
Y
V
G
S
E
T
E
F
Site 14
Y245
H
I
D
P
N
V
D
Y
Q
F
R
V
C
A
R
Site 15
S260
G
D
G
R
Q
E
W
S
P
W
S
V
P
Q
I
Site 16
S263
R
Q
E
W
S
P
W
S
V
P
Q
I
G
H
S
Site 17
T271
V
P
Q
I
G
H
S
T
L
V
P
H
E
W
T
Site 18
S285
T
A
G
F
E
G
Y
S
L
S
S
R
R
N
I
Site 19
S287
G
F
E
G
Y
S
L
S
S
R
R
N
I
A
L
Site 20
S288
F
E
G
Y
S
L
S
S
R
R
N
I
A
L
R
Site 21
S298
N
I
A
L
R
N
D
S
E
S
S
G
V
L
Y
Site 22
S300
A
L
R
N
D
S
E
S
S
G
V
L
Y
S
R
Site 23
Y305
S
E
S
S
G
V
L
Y
S
R
A
P
T
Y
F
Site 24
S306
E
S
S
G
V
L
Y
S
R
A
P
T
Y
F
C
Site 25
Y311
L
Y
S
R
A
P
T
Y
F
C
G
Q
T
L
T
Site 26
T323
T
L
T
F
R
V
E
T
V
G
Q
P
D
R
R
Site 27
S332
G
Q
P
D
R
R
D
S
I
G
V
C
A
E
K
Site 28
Y343
C
A
E
K
Q
D
G
Y
D
S
L
Q
R
D
Q
Site 29
S345
E
K
Q
D
G
Y
D
S
L
Q
R
D
Q
A
V
Site 30
S376
N
Q
L
P
A
V
T
S
G
S
T
V
T
F
D
Site 31
S393
A
V
T
L
G
T
T
S
N
N
E
G
G
H
F
Site 32
T405
G
H
F
K
L
R
V
T
I
S
S
N
N
R
E
Site 33
S407
F
K
L
R
V
T
I
S
S
N
N
R
E
V
V
Site 34
S408
K
L
R
V
T
I
S
S
N
N
R
E
V
V
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation