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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C5orf41
Full Name:
UPF0474 protein C5orf41
Alias:
CE041; DKFZp313F2319; DKFZp686G2059
Type:
Mass (Da):
72149
Number AA:
639
UniProt ID:
Q8IUR6
International Prot ID:
IPI00292678
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
P
Q
P
S
V
S
G
M
D
P
P
F
G
Site 2
S19
P
F
G
D
A
F
R
S
H
T
F
S
E
Q
T
Site 3
T21
G
D
A
F
R
S
H
T
F
S
E
Q
T
L
M
Site 4
S23
A
F
R
S
H
T
F
S
E
Q
T
L
M
S
T
Site 5
S36
S
T
D
L
L
A
N
S
S
D
P
D
F
M
Y
Site 6
S37
T
D
L
L
A
N
S
S
D
P
D
F
M
Y
E
Site 7
Y43
S
S
D
P
D
F
M
Y
E
L
D
R
E
M
N
Site 8
S61
N
P
R
D
N
F
L
S
L
E
D
C
K
D
I
Site 9
S73
K
D
I
E
N
L
E
S
F
T
D
V
L
D
N
Site 10
T99
D
T
Y
C
E
D
L
T
K
Y
T
K
L
T
S
Site 11
Y101
Y
C
E
D
L
T
K
Y
T
K
L
T
S
C
D
Site 12
T102
C
E
D
L
T
K
Y
T
K
L
T
S
C
D
I
Site 13
T112
T
S
C
D
I
W
G
T
K
E
V
D
Y
L
G
Site 14
Y117
W
G
T
K
E
V
D
Y
L
G
L
D
D
F
S
Site 15
S124
Y
L
G
L
D
D
F
S
S
P
Y
Q
D
E
E
Site 16
S125
L
G
L
D
D
F
S
S
P
Y
Q
D
E
E
V
Site 17
S134
Y
Q
D
E
E
V
I
S
K
T
P
T
L
A
Q
Site 18
T136
D
E
E
V
I
S
K
T
P
T
L
A
Q
L
N
Site 19
T138
E
V
I
S
K
T
P
T
L
A
Q
L
N
S
E
Site 20
S144
P
T
L
A
Q
L
N
S
E
D
S
Q
S
V
S
Site 21
S147
A
Q
L
N
S
E
D
S
Q
S
V
S
D
S
L
Site 22
S149
L
N
S
E
D
S
Q
S
V
S
D
S
L
Y
Y
Site 23
S151
S
E
D
S
Q
S
V
S
D
S
L
Y
Y
P
D
Site 24
S153
D
S
Q
S
V
S
D
S
L
Y
Y
P
D
S
L
Site 25
Y155
Q
S
V
S
D
S
L
Y
Y
P
D
S
L
F
S
Site 26
Y156
S
V
S
D
S
L
Y
Y
P
D
S
L
F
S
V
Site 27
S159
D
S
L
Y
Y
P
D
S
L
F
S
V
K
Q
N
Site 28
S171
K
Q
N
P
L
P
S
S
F
P
G
K
K
I
T
Site 29
S198
L
Q
A
E
V
P
L
S
D
C
V
Q
K
A
S
Site 30
S205
S
D
C
V
Q
K
A
S
K
P
T
S
S
T
Q
Site 31
S209
Q
K
A
S
K
P
T
S
S
T
Q
I
M
V
K
Site 32
Y234
F
H
V
E
C
K
D
Y
V
K
K
A
K
V
K
Site 33
S253
Q
Q
S
R
P
L
L
S
Q
I
H
T
D
A
A
Site 34
T257
P
L
L
S
Q
I
H
T
D
A
A
K
E
N
T
Site 35
Y266
A
A
K
E
N
T
C
Y
C
G
A
V
A
K
R
Site 36
T287
E
P
L
Q
G
H
A
T
P
A
L
P
F
K
E
Site 37
T295
P
A
L
P
F
K
E
T
Q
E
L
L
L
S
P
Site 38
S301
E
T
Q
E
L
L
L
S
P
L
P
Q
E
G
P
Site 39
S310
L
P
Q
E
G
P
G
S
L
A
A
G
E
S
S
Site 40
S316
G
S
L
A
A
G
E
S
S
S
L
S
A
S
T
Site 41
S317
S
L
A
A
G
E
S
S
S
L
S
A
S
T
S
Site 42
S320
A
G
E
S
S
S
L
S
A
S
T
S
V
S
D
Site 43
S322
E
S
S
S
L
S
A
S
T
S
V
S
D
S
S
Site 44
S324
S
S
L
S
A
S
T
S
V
S
D
S
S
Q
K
Site 45
S326
L
S
A
S
T
S
V
S
D
S
S
Q
K
K
E
Site 46
S328
A
S
T
S
V
S
D
S
S
Q
K
K
E
E
H
Site 47
S329
S
T
S
V
S
D
S
S
Q
K
K
E
E
H
N
Site 48
Y337
Q
K
K
E
E
H
N
Y
S
L
F
V
S
D
N
Site 49
S338
K
K
E
E
H
N
Y
S
L
F
V
S
D
N
L
Site 50
S342
H
N
Y
S
L
F
V
S
D
N
L
G
E
Q
P
Site 51
S353
G
E
Q
P
T
K
C
S
P
E
E
D
E
E
D
Site 52
S375
D
H
D
E
G
F
G
S
E
H
E
L
S
E
N
Site 53
S380
F
G
S
E
H
E
L
S
E
N
E
E
E
E
E
Site 54
Y392
E
E
E
E
E
E
D
Y
E
D
D
K
D
D
D
Site 55
S401
D
D
K
D
D
D
I
S
D
T
F
S
E
P
G
Site 56
T403
K
D
D
D
I
S
D
T
F
S
E
P
G
Y
E
Site 57
S405
D
D
I
S
D
T
F
S
E
P
G
Y
E
N
D
Site 58
Y409
D
T
F
S
E
P
G
Y
E
N
D
S
V
E
D
Site 59
S413
E
P
G
Y
E
N
D
S
V
E
D
L
K
E
V
Site 60
T421
V
E
D
L
K
E
V
T
S
I
S
S
R
K
R
Site 61
S422
E
D
L
K
E
V
T
S
I
S
S
R
K
R
G
Site 62
S424
L
K
E
V
T
S
I
S
S
R
K
R
G
K
R
Site 63
S425
K
E
V
T
S
I
S
S
R
K
R
G
K
R
R
Site 64
Y433
R
K
R
G
K
R
R
Y
F
W
E
Y
S
E
Q
Site 65
Y437
K
R
R
Y
F
W
E
Y
S
E
Q
L
T
P
S
Site 66
S438
R
R
Y
F
W
E
Y
S
E
Q
L
T
P
S
Q
Site 67
T442
W
E
Y
S
E
Q
L
T
P
S
Q
Q
E
R
M
Site 68
S444
Y
S
E
Q
L
T
P
S
Q
Q
E
R
M
L
R
Site 69
S453
Q
E
R
M
L
R
P
S
E
W
N
R
D
T
L
Site 70
T459
P
S
E
W
N
R
D
T
L
P
S
N
M
Y
Q
Site 71
Y465
D
T
L
P
S
N
M
Y
Q
K
N
G
L
H
H
Site 72
Y475
N
G
L
H
H
G
K
Y
A
V
K
K
S
R
R
Site 73
S480
G
K
Y
A
V
K
K
S
R
R
T
D
V
E
D
Site 74
T483
A
V
K
K
S
R
R
T
D
V
E
D
L
T
P
Site 75
T489
R
T
D
V
E
D
L
T
P
N
P
K
K
L
L
Site 76
S510
R
K
L
N
K
V
I
S
D
L
T
P
V
S
E
Site 77
T521
P
V
S
E
L
P
L
T
A
R
P
R
S
R
K
Site 78
S526
P
L
T
A
R
P
R
S
R
K
E
K
N
K
L
Site 79
T620
V
N
Q
V
L
E
K
T
A
E
G
N
P
T
G
Site 80
T626
K
T
A
E
G
N
P
T
G
G
L
V
G
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation