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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UNC5CL
Full Name:
UNC5C-like protein
Alias:
MGC34763; UN5CL; Unc-5 C-like; Unc-5C-like; Unc-5-like; ZU5 and death domain containing; ZU5 and death domain-containing protein; ZUD
Type:
Inhibitor protein
Mass (Da):
57818
Number AA:
518
UniProt ID:
Q8IV45
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
C
P
Q
E
S
S
F
Q
P
S
Q
F
L
Site 2
S11
Q
E
S
S
F
Q
P
S
Q
F
L
L
L
V
G
Site 3
S54
N
G
Q
E
E
P
V
S
Q
P
T
P
Q
L
E
Site 4
T57
E
E
P
V
S
Q
P
T
P
Q
L
E
N
E
V
Site 5
S65
P
Q
L
E
N
E
V
S
R
Q
H
L
P
A
T
Site 6
T72
S
R
Q
H
L
P
A
T
L
P
E
M
V
A
F
Site 7
T85
A
F
Y
Q
E
L
H
T
P
T
Q
G
Q
T
M
Site 8
S104
M
H
K
L
L
V
F
S
A
R
E
V
D
H
R
Site 9
S152
W
D
L
S
D
A
P
S
L
S
Q
A
Q
G
L
Site 10
S154
L
S
D
A
P
S
L
S
Q
A
Q
G
L
V
S
Site 11
S189
K
H
C
A
E
Q
P
S
H
A
R
T
Y
S
S
Site 12
T193
E
Q
P
S
H
A
R
T
Y
S
S
N
T
T
L
Site 13
Y194
Q
P
S
H
A
R
T
Y
S
S
N
T
T
L
L
Site 14
S195
P
S
H
A
R
T
Y
S
S
N
T
T
L
L
D
Site 15
S196
S
H
A
R
T
Y
S
S
N
T
T
L
L
D
A
Site 16
T199
R
T
Y
S
S
N
T
T
L
L
D
A
K
V
W
Site 17
S217
G
R
P
G
A
H
A
S
R
D
E
C
R
I
H
Site 18
S261
S
P
L
V
P
G
Q
S
H
L
Q
L
R
I
Y
Site 19
Y268
S
H
L
Q
L
R
I
Y
F
L
N
N
T
P
C
Site 20
T282
C
A
L
Q
W
A
L
T
N
E
Q
P
H
G
G
Site 21
T312
G
D
Q
C
L
K
L
T
Y
I
S
E
G
W
E
Site 22
Y313
D
Q
C
L
K
L
T
Y
I
S
E
G
W
E
N
Site 23
S358
A
D
E
N
E
D
C
S
A
L
T
N
E
I
I
Site 24
Y379
Q
D
G
L
E
T
K
Y
M
E
I
L
R
F
Q
Site 25
S388
E
I
L
R
F
Q
A
S
E
E
E
S
W
A
A
Site 26
S392
F
Q
A
S
E
E
E
S
W
A
A
P
P
P
V
Site 27
S400
W
A
A
P
P
P
V
S
Q
P
P
P
C
N
R
Site 28
S424
R
M
L
L
E
P
N
S
I
T
G
N
D
W
R
Site 29
S448
G
M
K
I
R
F
L
S
C
Q
R
S
P
A
A
Site 30
S467
L
F
E
E
Q
N
G
S
L
Q
E
L
H
Y
L
Site 31
Y473
G
S
L
Q
E
L
H
Y
L
M
T
V
M
E
R
Site 32
T476
Q
E
L
H
Y
L
M
T
V
M
E
R
L
D
C
Site 33
S485
M
E
R
L
D
C
A
S
A
I
Q
N
Y
L
S
Site 34
Y490
C
A
S
A
I
Q
N
Y
L
S
G
T
H
G
G
Site 35
S492
S
A
I
Q
N
Y
L
S
G
T
H
G
G
S
P
Site 36
T494
I
Q
N
Y
L
S
G
T
H
G
G
S
P
G
P
Site 37
S498
L
S
G
T
H
G
G
S
P
G
P
E
R
G
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation