PhosphoNET

           
Protein Info 
   
Short Name:  DENND1C
Full Name:  DENN domain-containing protein 1C
Alias:  Protein FAM31C
Type: 
Mass (Da):  87065
Number AA:  801
UniProt ID:  Q8IV53
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9ESRAEGGSPAVFDWF
Site 2S24FEAACPASLQEDPPI
Site 3S63DVEREPPSPAVQHFT
Site 4T124LLAQDQVTEAEELLQ
Site 5S137LQNLFQQSLSGPQAS
Site 6S139NLFQQSLSGPQASVG
Site 7S157GSGVTVSSGQGIPPP
Site 8T165GQGIPPPTRGNSKPL
Site 9S169PPPTRGNSKPLSCFV
Site 10S173RGNSKPLSCFVAPDS
Site 11S185PDSGRLPSIPENRNL
Site 12T294VLNVDANTLETTFND
Site 13T298DANTLETTFNDVQAL
Site 14S358PGQPVTFSEEVFLAQ
Site 15T410DQFEQEITGCGASSG
Site 16S416ITGCGASSGALRSYQ
Site 17Y422SSGALRSYQLWADNL
Site 18S439GGGALLHSVKAKTQP
Site 19Y452QPAVKNMYRSAKSGL
Site 20S454AVKNMYRSAKSGLKG
Site 21S464SGLKGVQSLLMYKDG
Site 22S473LMYKDGDSVLQRGGS
Site 23S480SVLQRGGSLRAPALP
Site 24S488LRAPALPSRSDRLQQ
Site 25S490APALPSRSDRLQQRL
Site 26T500LQQRLPITQHFGKNR
Site 27S512KNRPLRPSRRRQLEE
Site 28S522RQLEEGTSEPPGAGT
Site 29T529SEPPGAGTPPLSPED
Site 30S533GAGTPPLSPEDEGCP
Site 31S548WAEEALDSSFLGSGE
Site 32S549AEEALDSSFLGSGEE
Site 33S568SEILDSLSMGAKSAG
Site 34S573SLSMGAKSAGSLRPS
Site 35S576MGAKSAGSLRPSQSL
Site 36S580SAGSLRPSQSLDCCH
Site 37S582GSLRPSQSLDCCHRG
Site 38S593CHRGDLDSCFSLPNI
Site 39S596GDLDSCFSLPNIPRW
Site 40S619EPEPQPLSLPSLQNA
Site 41S622PQPLSLPSLQNASSL
Site 42S628PSLQNASSLDATSSS
Site 43T632NASSLDATSSSKDSR
Site 44S633ASSLDATSSSKDSRS
Site 45S634SSLDATSSSKDSRSQ
Site 46S635SLDATSSSKDSRSQL
Site 47S638ATSSSKDSRSQLIPS
Site 48S640SSSKDSRSQLIPSES
Site 49S647SQLIPSESDQEVTSP
Site 50S653ESDQEVTSPSQSSTA
Site 51S655DQEVTSPSQSSTASA
Site 52S657EVTSPSQSSTASADP
Site 53T659TSPSQSSTASADPSI
Site 54S661PSQSSTASADPSIWG
Site 55S665STASADPSIWGDPKP
Site 56S673IWGDPKPSPLTEPLI
Site 57T676DPKPSPLTEPLILHL
Site 58T684EPLILHLTPSHKAAE
Site 59S686LILHLTPSHKAAEDS
Site 60T700STAQENPTPWLSTAP
Site 61S704ENPTPWLSTAPTEPS
Site 62T708PWLSTAPTEPSPPES
Site 63S711STAPTEPSPPESPQI
Site 64S715TEPSPPESPQILAPT
Site 65S732NFDIAWTSQPLDPSS
Site 66S738TSQPLDPSSDPSSLE
Site 67S739SQPLDPSSDPSSLED
Site 68S742LDPSSDPSSLEDPRA
Site 69S743DPSSDPSSLEDPRAR
Site 70S773EEPGALNSPATPTSN
Site 71T776GALNSPATPTSNCQK
Site 72S779NSPATPTSNCQKSQP
Site 73S784PTSNCQKSQPSSRPR
Site 74S787NCQKSQPSSRPRVAD
Site 75S788CQKSQPSSRPRVADL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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