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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM22A
Full Name:
Protein FAM22A
Alias:
Type:
Mass (Da):
93890
Number AA:
878
UniProt ID:
Q8IVF1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
E
V
K
G
P
S
G
R
S
F
C
C
E
Site 2
S10
V
K
G
P
S
G
R
S
F
C
C
E
S
E
G
Site 3
S21
E
S
E
G
Q
F
K
S
C
L
K
R
H
T
P
Site 4
T27
K
S
C
L
K
R
H
T
P
S
L
L
L
P
S
Site 5
S29
C
L
K
R
H
T
P
S
L
L
L
P
S
S
W
Site 6
S34
T
P
S
L
L
L
P
S
S
W
K
G
N
S
G
Site 7
S35
P
S
L
L
L
P
S
S
W
K
G
N
S
G
S
Site 8
S40
P
S
S
W
K
G
N
S
G
S
C
L
M
A
E
Site 9
S42
S
W
K
G
N
S
G
S
C
L
M
A
E
A
L
Site 10
S53
A
E
A
L
H
R
M
S
P
T
P
N
S
C
P
Site 11
T55
A
L
H
R
M
S
P
T
P
N
S
C
P
L
P
Site 12
S58
R
M
S
P
T
P
N
S
C
P
L
P
L
P
L
Site 13
S89
F
S
L
F
Q
L
D
S
G
A
S
G
E
P
G
Site 14
T113
S
H
C
G
N
C
Q
T
A
V
V
S
A
Q
P
Site 15
S125
A
Q
P
E
G
M
A
S
N
G
A
Y
P
A
L
Site 16
S196
E
Q
D
G
C
G
P
S
G
A
G
A
S
N
V
Site 17
S201
G
P
S
G
A
G
A
S
N
V
F
V
Q
M
R
Site 18
S274
Q
A
C
E
G
G
W
S
Q
G
L
P
L
P
P
Site 19
S294
A
Q
L
P
P
I
V
S
Q
G
N
A
G
P
W
Site 20
S310
Q
G
A
H
G
E
G
S
L
A
S
S
Q
A
K
Site 21
S314
G
E
G
S
L
A
S
S
Q
A
K
A
P
P
D
Site 22
S323
A
K
A
P
P
D
D
S
C
N
P
R
S
V
Y
Site 23
S328
D
D
S
C
N
P
R
S
V
Y
E
N
F
R
L
Site 24
Y330
S
C
N
P
R
S
V
Y
E
N
F
R
L
W
Q
Site 25
Y339
N
F
R
L
W
Q
H
Y
K
P
L
A
R
R
H
Site 26
S350
A
R
R
H
L
P
Q
S
P
D
T
E
A
L
S
Site 27
T353
H
L
P
Q
S
P
D
T
E
A
L
S
C
F
L
Site 28
T373
S
L
A
R
R
K
P
T
M
T
L
E
E
G
L
Site 29
T375
A
R
R
K
P
T
M
T
L
E
E
G
L
W
R
Site 30
S391
M
R
E
W
Q
H
T
S
N
F
D
R
M
I
F
Site 31
Y399
N
F
D
R
M
I
F
Y
E
M
A
E
K
F
L
Site 32
T433
Q
C
L
P
P
P
A
T
P
R
L
E
P
R
G
Site 33
Y452
E
V
V
K
Q
P
V
Y
L
P
S
K
A
G
P
Site 34
S455
K
Q
P
V
Y
L
P
S
K
A
G
P
K
A
P
Site 35
T476
P
R
P
Q
R
P
V
T
K
A
R
R
P
P
P
Site 36
T491
R
P
H
R
R
A
E
T
K
A
R
L
P
P
P
Site 37
Y520
P
P
E
V
V
Q
E
Y
V
D
I
M
E
E
L
Site 38
T535
L
G
P
S
L
G
A
T
G
E
P
E
K
Q
R
Site 39
T556
Q
P
Q
E
E
D
W
T
P
P
D
P
G
L
L
Site 40
S564
P
P
D
P
G
L
L
S
Y
T
D
K
L
C
S
Site 41
Y565
P
D
P
G
L
L
S
Y
T
D
K
L
C
S
Q
Site 42
S571
S
Y
T
D
K
L
C
S
Q
K
D
F
V
T
K
Site 43
S593
Q
F
L
E
E
L
L
S
P
D
P
Q
M
D
F
Site 44
S604
Q
M
D
F
L
A
L
S
Q
E
L
E
Q
E
E
Site 45
T614
L
E
Q
E
E
G
L
T
L
A
Q
L
V
E
K
Site 46
T640
R
A
A
P
S
R
G
T
A
R
L
D
S
S
S
Site 47
S645
R
G
T
A
R
L
D
S
S
S
S
K
F
A
A
Site 48
S646
G
T
A
R
L
D
S
S
S
S
K
F
A
A
G
Site 49
S647
T
A
R
L
D
S
S
S
S
K
F
A
A
G
Q
Site 50
S648
A
R
L
D
S
S
S
S
K
F
A
A
G
Q
G
Site 51
T671
Q
Q
G
V
G
M
E
T
C
P
P
Q
T
T
A
Site 52
T676
M
E
T
C
P
P
Q
T
T
A
R
D
S
Q
G
Site 53
T677
E
T
C
P
P
Q
T
T
A
R
D
S
Q
G
R
Site 54
S681
P
Q
T
T
A
R
D
S
Q
G
R
G
R
A
H
Site 55
T689
Q
G
R
G
R
A
H
T
G
M
A
R
S
K
D
Site 56
T715
G
L
R
A
A
R
P
T
S
P
P
Q
D
H
R
Site 57
S716
L
R
A
A
R
P
T
S
P
P
Q
D
H
R
P
Site 58
T724
P
P
Q
D
H
R
P
T
C
P
G
V
G
T
K
Site 59
S740
A
L
D
L
P
G
G
S
P
V
R
E
S
H
G
Site 60
S745
G
G
S
P
V
R
E
S
H
G
L
A
Q
G
S
Site 61
S753
H
G
L
A
Q
G
S
S
E
E
E
E
L
P
S
Site 62
S760
S
E
E
E
E
L
P
S
L
A
F
L
L
G
S
Site 63
S767
S
L
A
F
L
L
G
S
Q
H
K
L
L
P
W
Site 64
S784
P
Q
S
P
V
P
A
S
G
L
L
S
P
E
K
Site 65
S788
V
P
A
S
G
L
L
S
P
E
K
W
G
P
Q
Site 66
S802
Q
G
T
H
Q
F
P
S
A
E
R
R
G
L
N
Site 67
S813
R
G
L
N
L
A
P
S
P
A
N
K
A
K
K
Site 68
S826
K
K
R
P
L
F
G
S
L
S
P
A
E
K
T
Site 69
S828
R
P
L
F
G
S
L
S
P
A
E
K
T
P
H
Site 70
T833
S
L
S
P
A
E
K
T
P
H
P
G
P
G
L
Site 71
S843
P
G
P
G
L
R
V
S
G
E
Q
S
L
T
W
Site 72
S847
L
R
V
S
G
E
Q
S
L
T
W
G
L
G
G
Site 73
T849
V
S
G
E
Q
S
L
T
W
G
L
G
G
P
S
Site 74
S856
T
W
G
L
G
G
P
S
Q
S
Q
K
R
K
G
Site 75
S858
G
L
G
G
P
S
Q
S
Q
K
R
K
G
D
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation