KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FMNL3
Full Name:
Formin-like protein 3
Alias:
DKFZp762B245; FHOD3; Formin 2 domain-containing 3; Formin homology 2 domain-containing protein 3; Formin-like 3; MGC45819; WBP3; WW domain binding 3; WW domain-binding protein 3
Type:
Unknown function
Mass (Da):
117213
Number AA:
1028
UniProt ID:
Q8IVF7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0017048
GO:0003779
PhosphoSite+
KinaseNET
Biological Process:
GO:0030036
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
G
N
L
E
S
A
E
G
V
P
G
E
Site 2
S44
R
F
A
L
V
L
S
S
M
N
L
P
P
D
K
Site 3
Y58
K
A
R
L
L
R
Q
Y
D
N
E
K
K
W
D
Site 4
T81
Q
V
K
N
P
P
H
T
Y
I
Q
K
L
Q
S
Site 5
S88
T
Y
I
Q
K
L
Q
S
F
L
D
P
S
V
T
Site 6
S93
L
Q
S
F
L
D
P
S
V
T
R
K
K
F
R
Site 7
T95
S
F
L
D
P
S
V
T
R
K
K
F
R
R
R
Site 8
S106
F
R
R
R
V
Q
E
S
T
K
V
L
R
E
L
Site 9
T107
R
R
R
V
Q
E
S
T
K
V
L
R
E
L
E
Site 10
S116
V
L
R
E
L
E
I
S
L
R
T
N
H
I
G
Site 11
S159
F
D
F
E
G
L
E
S
G
D
D
G
A
F
D
Site 12
S170
G
A
F
D
K
L
R
S
W
S
R
S
I
E
D
Site 13
S172
F
D
K
L
R
S
W
S
R
S
I
E
D
L
Q
Site 14
S174
K
L
R
S
W
S
R
S
I
E
D
L
Q
P
P
Site 15
S182
I
E
D
L
Q
P
P
S
A
L
S
A
P
F
T
Site 16
S185
L
Q
P
P
S
A
L
S
A
P
F
T
N
S
L
Site 17
S191
L
S
A
P
F
T
N
S
L
A
R
S
A
R
Q
Site 18
S195
F
T
N
S
L
A
R
S
A
R
Q
S
V
L
R
Site 19
S199
L
A
R
S
A
R
Q
S
V
L
R
Y
S
T
L
Site 20
Y203
A
R
Q
S
V
L
R
Y
S
T
L
P
G
R
R
Site 21
S204
R
Q
S
V
L
R
Y
S
T
L
P
G
R
R
A
Site 22
T205
Q
S
V
L
R
Y
S
T
L
P
G
R
R
A
L
Site 23
S215
G
R
R
A
L
K
N
S
R
L
V
S
Q
K
D
Site 24
S219
L
K
N
S
R
L
V
S
Q
K
D
D
V
H
V
Site 25
S257
A
V
N
E
I
A
L
S
L
N
N
K
N
P
R
Site 26
Y309
R
F
E
K
L
M
E
Y
F
R
N
E
D
S
N
Site 27
Y345
N
F
R
V
H
L
Q
Y
E
F
T
K
L
G
L
Site 28
S359
L
E
E
F
L
Q
K
S
R
H
T
E
S
E
K
Site 29
T362
F
L
Q
K
S
R
H
T
E
S
E
K
L
Q
V
Site 30
T390
G
L
L
E
D
A
E
T
K
N
V
A
L
E
K
Site 31
S406
E
E
L
E
E
H
V
S
H
L
T
E
K
L
L
Site 32
T443
E
L
E
S
I
K
E
T
Y
E
N
T
S
H
Q
Site 33
Y444
L
E
S
I
K
E
T
Y
E
N
T
S
H
Q
V
Site 34
T453
N
T
S
H
Q
V
H
T
L
R
R
L
I
K
E
Site 35
S483
R
G
L
E
S
V
D
S
E
A
L
A
R
V
G
Site 36
S495
R
V
G
P
A
E
L
S
E
G
M
P
P
S
D
Site 37
S501
L
S
E
G
M
P
P
S
D
L
D
L
L
A
P
Site 38
T567
R
I
K
K
P
I
K
T
K
F
R
L
P
V
F
Site 39
T587
K
P
N
Q
I
S
G
T
V
F
S
E
L
D
D
Site 40
T612
K
F
E
E
L
F
K
T
K
A
Q
G
P
A
L
Site 41
S624
P
A
L
D
L
I
C
S
K
N
K
T
A
Q
K
Site 42
T628
L
I
C
S
K
N
K
T
A
Q
K
A
A
S
K
Site 43
T650
R
A
K
N
L
A
I
T
L
R
K
A
G
R
S
Site 44
S657
T
L
R
K
A
G
R
S
A
E
E
I
C
R
A
Site 45
T687
C
L
M
R
F
L
P
T
E
A
E
V
K
L
L
Site 46
Y697
E
V
K
L
L
R
Q
Y
E
R
E
R
Q
P
L
Site 47
T724
F
S
K
V
E
R
L
T
Q
R
M
A
G
M
A
Site 48
S760
A
S
A
S
V
K
S
S
Q
K
L
K
Q
M
L
Site 49
Y776
I
I
L
A
L
G
N
Y
M
N
S
S
K
R
G
Site 50
S780
L
G
N
Y
M
N
S
S
K
R
G
A
V
Y
G
Site 51
Y786
S
S
K
R
G
A
V
Y
G
F
K
L
Q
S
L
Site 52
T799
S
L
D
L
L
L
D
T
K
S
T
D
R
K
M
Site 53
S801
D
L
L
L
D
T
K
S
T
D
R
K
M
T
L
Site 54
T802
L
L
L
D
T
K
S
T
D
R
K
M
T
L
L
Site 55
T807
K
S
T
D
R
K
M
T
L
L
H
F
I
A
L
Site 56
Y820
A
L
T
V
K
E
K
Y
P
D
L
A
N
F
W
Site 57
S863
E
L
I
R
R
E
C
S
I
H
D
N
S
V
L
Site 58
S868
E
C
S
I
H
D
N
S
V
L
R
N
F
L
S
Site 59
S875
S
V
L
R
N
F
L
S
T
N
E
G
K
L
D
Site 60
T876
V
L
R
N
F
L
S
T
N
E
G
K
L
D
K
Site 61
T890
K
L
Q
R
D
A
K
T
A
E
E
A
Y
N
A
Site 62
Y901
A
Y
N
A
V
V
R
Y
F
G
E
S
P
K
T
Site 63
S905
V
V
R
Y
F
G
E
S
P
K
T
T
P
P
S
Site 64
T908
Y
F
G
E
S
P
K
T
T
P
P
S
V
F
F
Site 65
T909
F
G
E
S
P
K
T
T
P
P
S
V
F
F
P
Site 66
Y925
F
V
R
F
I
R
S
Y
K
E
A
E
Q
E
N
Site 67
T958
A
K
K
L
D
A
K
T
P
S
Q
R
N
K
W
Site 68
S960
K
L
D
A
K
T
P
S
Q
R
N
K
W
Q
Q
Site 69
Y986
A
K
E
H
R
P
V
Y
E
G
K
D
G
T
I
Site 70
T992
V
Y
E
G
K
D
G
T
I
E
D
I
I
T
V
Site 71
T1006
V
L
K
S
V
P
F
T
A
R
T
A
K
R
G
Site 72
T1009
S
V
P
F
T
A
R
T
A
K
R
G
S
R
F
Site 73
S1014
A
R
T
A
K
R
G
S
R
F
F
C
D
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation