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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOSTRIN
Full Name:
Nostrin
Alias:
BM247 homolog; DaIP2; Endothelial nitric oxide synthase traffic inducer; ENOS traffic inducer; ENOS trafficking inducer; MGC20702; Nitric oxide synthase trafficker; NOSTN
Type:
Adaptor/scaffold
Mass (Da):
57732
Number AA:
506
UniProt ID:
Q8IVI9
International Prot ID:
IPI00549783
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016023
GO:0005856
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006897
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
D
P
L
T
D
C
P
Y
N
K
V
Y
K
N
L
Site 2
S54
K
G
L
Q
K
L
A
S
K
L
S
K
A
L
Q
Site 3
S66
A
L
Q
N
T
R
K
S
C
V
S
S
A
W
A
Site 4
S69
N
T
R
K
S
C
V
S
S
A
W
A
W
A
S
Site 5
S70
T
R
K
S
C
V
S
S
A
W
A
W
A
S
E
Site 6
S76
S
S
A
W
A
W
A
S
E
G
M
K
S
T
A
Site 7
S81
W
A
S
E
G
M
K
S
T
A
D
L
H
Q
K
Site 8
Y102
L
E
A
I
K
P
T
Y
Q
V
L
N
V
Q
E
Site 9
S114
V
Q
E
K
K
R
K
S
L
D
N
E
V
E
K
Site 10
T122
L
D
N
E
V
E
K
T
A
N
L
V
I
S
N
Site 11
S160
L
V
E
S
S
K
Q
S
M
T
E
K
E
K
R
Site 12
T174
R
K
L
L
N
K
L
T
K
S
T
E
K
L
E
Site 13
S176
L
L
N
K
L
T
K
S
T
E
K
L
E
K
E
Site 14
T177
L
N
K
L
T
K
S
T
E
K
L
E
K
E
D
Site 15
Y187
L
E
K
E
D
E
N
Y
Y
Q
K
N
M
A
G
Site 16
Y188
E
K
E
D
E
N
Y
Y
Q
K
N
M
A
G
Y
Site 17
T204
T
R
L
K
W
E
N
T
L
E
N
C
Y
Q
S
Site 18
Y230
L
C
N
N
L
N
Q
Y
S
Q
H
I
S
L
F
Site 19
S235
N
Q
Y
S
Q
H
I
S
L
F
G
Q
T
L
T
Site 20
S272
M
E
E
T
A
I
L
S
T
E
N
K
S
E
F
Site 21
T282
N
K
S
E
F
L
L
T
D
Y
F
E
E
D
P
Site 22
Y284
S
E
F
L
L
T
D
Y
F
E
E
D
P
N
S
Site 23
S291
Y
F
E
E
D
P
N
S
A
M
D
K
E
R
R
Site 24
S300
M
D
K
E
R
R
K
S
L
L
K
P
K
L
L
Site 25
T329
G
L
E
R
M
L
K
T
Y
S
S
T
S
S
F
Site 26
Y330
L
E
R
M
L
K
T
Y
S
S
T
S
S
F
S
Site 27
S331
E
R
M
L
K
T
Y
S
S
T
S
S
F
S
D
Site 28
S332
R
M
L
K
T
Y
S
S
T
S
S
F
S
D
A
Site 29
S334
L
K
T
Y
S
S
T
S
S
F
S
D
A
K
S
Site 30
S335
K
T
Y
S
S
T
S
S
F
S
D
A
K
S
Q
Site 31
S337
Y
S
S
T
S
S
F
S
D
A
K
S
Q
K
D
Site 32
S341
S
S
F
S
D
A
K
S
Q
K
D
T
A
A
L
Site 33
T345
D
A
K
S
Q
K
D
T
A
A
L
M
D
E
N
Site 34
Y364
D
L
L
E
A
N
S
Y
K
L
S
S
M
L
A
Site 35
S367
E
A
N
S
Y
K
L
S
S
M
L
A
E
L
E
Site 36
S380
L
E
Q
R
P
Q
P
S
H
P
C
S
N
S
I
Site 37
S386
P
S
H
P
C
S
N
S
I
F
R
W
R
E
K
Site 38
T396
R
W
R
E
K
E
H
T
H
S
Y
V
K
I
S
Site 39
S398
R
E
K
E
H
T
H
S
Y
V
K
I
S
R
P
Site 40
Y399
E
K
E
H
T
H
S
Y
V
K
I
S
R
P
F
Site 41
S416
K
R
L
E
N
I
V
S
K
A
S
S
G
G
Q
Site 42
S420
N
I
V
S
K
A
S
S
G
G
Q
S
N
P
G
Site 43
S424
K
A
S
S
G
G
Q
S
N
P
G
S
S
T
P
Site 44
S428
G
G
Q
S
N
P
G
S
S
T
P
A
P
G
A
Site 45
T430
Q
S
N
P
G
S
S
T
P
A
P
G
A
A
Q
Site 46
Y447
S
R
L
C
K
A
L
Y
S
F
Q
A
R
Q
D
Site 47
S448
R
L
C
K
A
L
Y
S
F
Q
A
R
Q
D
D
Site 48
S479
E
E
G
W
W
F
G
S
L
N
G
K
K
G
H
Site 49
Y491
K
G
H
F
P
A
A
Y
V
E
E
L
P
S
N
Site 50
S497
A
Y
V
E
E
L
P
S
N
A
G
N
T
A
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation