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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LEPREL2
Full Name:
Prolyl 3-hydroxylase 3
Alias:
Leprecan-like protein 2;Protein B
Type:
Mass (Da):
81837
Number AA:
736
UniProt ID:
Q8IVL6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
L
L
L
P
P
P
G
S
P
E
P
P
G
L
T
Site 2
S29
P
P
G
L
T
Q
L
S
P
G
A
P
P
Q
A
Site 3
Y41
P
Q
A
P
D
L
L
Y
A
D
G
L
R
A
Y
Site 4
S101
L
G
A
P
E
P
D
S
G
P
G
P
T
Q
G
Site 5
S109
G
P
G
P
T
Q
G
S
W
E
R
Q
L
L
R
Site 6
T126
L
R
R
A
D
C
L
T
Q
C
A
A
R
R
L
Site 7
S145
A
A
R
L
R
V
G
S
A
L
R
D
A
F
R
Site 8
Y157
A
F
R
R
R
E
P
Y
N
Y
L
Q
R
A
Y
Site 9
Y159
R
R
R
E
P
Y
N
Y
L
Q
R
A
Y
Y
Q
Site 10
Y164
Y
N
Y
L
Q
R
A
Y
Y
Q
L
K
K
L
D
Site 11
Y165
N
Y
L
Q
R
A
Y
Y
Q
L
K
K
L
D
L
Site 12
Y197
M
R
E
D
M
A
K
Y
R
R
M
S
G
V
R
Site 13
S201
M
A
K
Y
R
R
M
S
G
V
R
P
Q
S
F
Site 14
S207
M
S
G
V
R
P
Q
S
F
R
D
L
E
T
P
Site 15
T213
Q
S
F
R
D
L
E
T
P
P
H
W
A
A
Y
Site 16
T222
P
H
W
A
A
Y
D
T
G
L
E
L
L
G
R
Site 17
S246
L
E
E
A
L
Q
G
S
L
A
Q
M
E
S
C
Site 18
S252
G
S
L
A
Q
M
E
S
C
R
A
D
C
E
G
Site 19
Y280
A
A
S
Q
G
G
L
Y
E
A
I
A
G
H
W
Site 20
T301
R
Q
R
C
V
G
E
T
A
T
R
P
G
R
S
Site 21
S308
T
A
T
R
P
G
R
S
F
P
V
P
D
F
L
Site 22
Y359
A
K
R
A
L
N
Q
Y
Q
A
Q
L
G
E
P
Site 23
S383
I
Q
R
F
I
L
R
S
L
G
E
K
R
Q
L
Site 24
Y391
L
G
E
K
R
Q
L
Y
Y
A
M
E
H
L
G
Site 25
T399
Y
A
M
E
H
L
G
T
S
F
K
D
P
D
P
Site 26
S400
A
M
E
H
L
G
T
S
F
K
D
P
D
P
W
Site 27
T408
F
K
D
P
D
P
W
T
P
A
A
L
I
P
E
Site 28
T441
P
V
K
P
K
P
L
T
Y
W
K
D
V
L
L
Site 29
S464
D
S
R
Q
L
N
G
S
E
R
A
V
L
D
G
Site 30
Y497
G
A
G
A
R
S
G
Y
R
G
R
R
S
P
H
Site 31
S502
S
G
Y
R
G
R
R
S
P
H
T
P
H
E
R
Site 32
T505
R
G
R
R
S
P
H
T
P
H
E
R
F
E
G
Site 33
T514
H
E
R
F
E
G
L
T
V
L
K
A
A
Q
L
Site 34
T526
A
Q
L
A
R
A
G
T
V
G
S
Q
G
A
K
Site 35
T544
E
V
S
E
R
V
R
T
L
T
Q
A
Y
F
S
Site 36
T546
S
E
R
V
R
T
L
T
Q
A
Y
F
S
P
E
Site 37
Y549
V
R
T
L
T
Q
A
Y
F
S
P
E
R
P
L
Site 38
S551
T
L
T
Q
A
Y
F
S
P
E
R
P
L
H
L
Site 39
S559
P
E
R
P
L
H
L
S
F
T
H
L
V
C
R
Site 40
T594
N
C
V
L
D
P
D
T
G
E
C
W
R
E
P
Site 41
Y604
C
W
R
E
P
P
A
Y
T
Y
R
D
Y
S
G
Site 42
Y606
R
E
P
P
A
Y
T
Y
R
D
Y
S
G
L
L
Site 43
Y609
P
A
Y
T
Y
R
D
Y
S
G
L
L
Y
L
N
Site 44
S610
A
Y
T
Y
R
D
Y
S
G
L
L
Y
L
N
D
Site 45
Y614
R
D
Y
S
G
L
L
Y
L
N
D
D
F
Q
G
Site 46
T633
F
T
E
P
N
A
L
T
V
T
A
R
V
R
P
Site 47
T635
E
P
N
A
L
T
V
T
A
R
V
R
P
R
C
Site 48
S649
C
G
R
L
V
A
F
S
S
G
V
E
N
P
H
Site 49
S650
G
R
L
V
A
F
S
S
G
V
E
N
P
H
G
Site 50
S707
E
E
E
E
E
M
P
S
K
D
P
S
P
E
P
Site 51
S711
E
M
P
S
K
D
P
S
P
E
P
P
S
R
R
Site 52
S716
D
P
S
P
E
P
P
S
R
R
H
Q
R
V
Q
Site 53
T726
H
Q
R
V
Q
D
K
T
G
R
A
P
R
V
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation