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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SERPINA12
Full Name:
Serpin A12
Alias:
OL-64; Serpin A12; Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin) member 12; SPA12; Vaspin; Visceral adipose tissue-derived serine protease inhibitor; Visceral adipose-specific serpin
Type:
Inhibitor protein
Mass (Da):
47156
Number AA:
414
UniProt ID:
Q8IW75
International Prot ID:
IPI00219476
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0004867
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
V
K
G
L
L
K
P
S
F
S
P
R
N
Y
K
Site 2
S26
G
L
L
K
P
S
F
S
P
R
N
Y
K
A
L
Site 3
Y30
P
S
F
S
P
R
N
Y
K
A
L
S
E
V
Q
Site 4
S34
P
R
N
Y
K
A
L
S
E
V
Q
G
W
K
Q
Site 5
S93
L
C
L
G
A
Q
D
S
T
L
D
E
I
K
Q
Site 6
T94
C
L
G
A
Q
D
S
T
L
D
E
I
K
Q
G
Site 7
Y118
D
L
H
E
G
F
H
Y
I
I
H
E
L
T
Q
Site 8
T127
I
H
E
L
T
Q
K
T
Q
D
L
K
L
S
I
Site 9
S159
E
D
A
K
N
F
Y
S
A
E
T
I
L
T
N
Site 10
T165
Y
S
A
E
T
I
L
T
N
F
Q
N
L
E
M
Site 11
S182
K
Q
I
N
D
F
I
S
Q
K
T
H
G
K
I
Site 12
S234
D
F
F
L
E
K
N
S
S
V
K
V
P
M
M
Site 13
Y251
S
G
I
Y
Q
V
G
Y
D
D
K
L
S
C
T
Site 14
T291
E
K
G
L
Q
V
D
T
F
S
R
W
K
T
L
Site 15
S293
G
L
Q
V
D
T
F
S
R
W
K
T
L
L
S
Site 16
T297
D
T
F
S
R
W
K
T
L
L
S
R
R
V
V
Site 17
S300
S
R
W
K
T
L
L
S
R
R
V
V
D
V
S
Site 18
S307
S
R
R
V
V
D
V
S
V
P
R
L
H
M
T
Site 19
T316
P
R
L
H
M
T
G
T
F
D
L
K
K
T
L
Site 20
S329
T
L
S
Y
I
G
V
S
K
I
F
E
E
H
G
Site 21
T339
F
E
E
H
G
D
L
T
K
I
A
P
H
R
S
Site 22
T365
L
K
M
D
E
R
G
T
E
G
A
A
G
T
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation