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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR75
Full Name:
WD repeat-containing protein 75
Alias:
FLJ12519; NET16; WD repeat domain 75
Type:
Uncharacterized protein
Mass (Da):
94499
Number AA:
830
UniProt ID:
Q8IWA0
International Prot ID:
IPI0021724
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
N
F
R
R
A
V
F
S
A
D
S
K
Y
I
F
Site 2
Y42
S
G
D
F
V
K
V
Y
S
T
V
T
E
E
C
Site 3
T44
D
F
V
K
V
Y
S
T
V
T
E
E
C
V
H
Site 4
Y74
P
N
N
H
L
Q
L
Y
S
C
S
L
D
G
T
Site 5
S131
P
D
I
F
Q
L
V
S
V
K
L
P
K
S
S
Site 6
S137
V
S
V
K
L
P
K
S
S
S
Q
E
V
E
A
Site 7
S139
V
K
L
P
K
S
S
S
Q
E
V
E
A
K
E
Site 8
Y153
E
L
S
F
V
L
D
Y
I
N
Q
S
P
K
C
Site 9
S179
A
V
R
E
F
Y
L
S
V
Y
F
F
K
K
K
Site 10
Y181
R
E
F
Y
L
S
V
Y
F
F
K
K
K
T
T
Site 11
T187
V
Y
F
F
K
K
K
T
T
S
R
F
T
L
S
Site 12
T188
Y
F
F
K
K
K
T
T
S
R
F
T
L
S
S
Site 13
S189
F
F
K
K
K
T
T
S
R
F
T
L
S
S
S
Site 14
T192
K
K
T
T
S
R
F
T
L
S
S
S
R
N
K
Site 15
S194
T
T
S
R
F
T
L
S
S
S
R
N
K
K
H
Site 16
S195
T
S
R
F
T
L
S
S
S
R
N
K
K
H
A
Site 17
S196
S
R
F
T
L
S
S
S
R
N
K
K
H
A
K
Site 18
Y234
I
R
L
W
R
N
F
Y
D
D
K
K
Y
T
Y
Site 19
S270
L
L
S
G
G
R
E
S
V
L
V
E
W
R
D
Site 20
T279
L
V
E
W
R
D
A
T
E
K
N
K
E
F
L
Site 21
S308
A
G
D
L
F
C
T
S
H
S
D
N
K
I
I
Site 22
Y361
K
P
G
H
L
Q
F
Y
S
L
Q
S
D
K
Q
Site 23
S362
P
G
H
L
Q
F
Y
S
L
Q
S
D
K
Q
L
Site 24
Y370
L
Q
S
D
K
Q
L
Y
N
L
D
I
I
Q
Q
Site 25
Y383
Q
Q
E
Y
I
N
D
Y
G
L
I
Q
I
E
L
Site 26
T404
C
F
G
N
W
L
A
T
V
E
Q
R
Q
E
K
Site 27
T413
E
Q
R
Q
E
K
E
T
E
L
E
L
Q
M
K
Site 28
T460
A
E
K
S
E
Q
P
T
L
V
T
A
S
K
D
Site 29
Y482
L
T
D
D
S
D
I
Y
K
K
A
V
G
W
T
Site 30
Y555
G
R
L
T
C
S
K
Y
L
L
G
A
T
E
N
Site 31
S592
V
M
E
P
D
P
N
S
E
N
I
A
A
I
S
Site 32
S599
S
E
N
I
A
A
I
S
Q
S
S
V
G
S
D
Site 33
Y619
P
S
E
P
R
P
L
Y
I
Q
K
G
I
S
R
Site 34
S642
V
P
R
D
V
P
E
S
F
T
S
E
A
Y
Q
Site 35
S645
D
V
P
E
S
F
T
S
E
A
Y
Q
W
L
N
Site 36
Y657
W
L
N
R
S
Q
F
Y
F
L
T
K
S
Q
S
Site 37
T660
R
S
Q
F
Y
F
L
T
K
S
Q
S
L
L
T
Site 38
S664
Y
F
L
T
K
S
Q
S
L
L
T
F
S
T
K
Site 39
T667
T
K
S
Q
S
L
L
T
F
S
T
K
S
P
E
Site 40
T670
Q
S
L
L
T
F
S
T
K
S
P
E
E
K
L
Site 41
S672
L
L
T
F
S
T
K
S
P
E
E
K
L
T
P
Site 42
T678
K
S
P
E
E
K
L
T
P
T
S
K
Q
L
L
Site 43
S689
K
Q
L
L
A
E
E
S
L
P
T
T
P
F
Y
Site 44
T692
L
A
E
E
S
L
P
T
T
P
F
Y
F
I
L
Site 45
T693
A
E
E
S
L
P
T
T
P
F
Y
F
I
L
G
Site 46
Y696
S
L
P
T
T
P
F
Y
F
I
L
G
K
H
R
Site 47
S758
F
V
N
S
L
L
L
S
K
E
T
K
S
A
K
Site 48
S763
L
L
S
K
E
T
K
S
A
K
E
I
P
E
D
Site 49
S779
D
M
E
E
E
K
E
S
E
D
S
D
E
E
N
Site 50
S782
E
E
K
E
S
E
D
S
D
E
E
N
D
F
T
Site 51
T789
S
D
E
E
N
D
F
T
E
K
V
Q
D
T
S
Site 52
T795
F
T
E
K
V
Q
D
T
S
N
T
G
L
G
E
Site 53
S796
T
E
K
V
Q
D
T
S
N
T
G
L
G
E
D
Site 54
T798
K
V
Q
D
T
S
N
T
G
L
G
E
D
I
I
Site 55
S809
E
D
I
I
H
Q
L
S
K
S
E
E
K
E
L
Site 56
S811
I
I
H
Q
L
S
K
S
E
E
K
E
L
R
K
Site 57
Y824
R
K
F
R
K
I
D
Y
S
W
I
A
A
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation