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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAP7D3
Full Name:
MAP7 domain-containing protein 3
Alias:
FLJ12401; FLJ12649; MA7D3; MAP7 domain containing 3; MAP7 domain-containing protein 3
Type:
Uncharacterized protein
Mass (Da):
98429
Number AA:
876
UniProt ID:
Q8IWC1
International Prot ID:
IPI00847637
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
A
A
A
G
A
G
G
S
P
S
L
R
E
L
R
Site 2
S15
A
G
A
G
G
S
P
S
L
R
E
L
R
A
R
Site 3
T45
D
V
V
N
R
V
A
T
H
S
S
N
I
R
S
Site 4
S47
V
N
R
V
A
T
H
S
S
N
I
R
S
T
F
Site 5
S48
N
R
V
A
T
H
S
S
N
I
R
S
T
F
K
Site 6
S52
T
H
S
S
N
I
R
S
T
F
K
P
V
I
D
Site 7
T53
H
S
S
N
I
R
S
T
F
K
P
V
I
D
G
Site 8
S61
F
K
P
V
I
D
G
S
M
L
K
N
D
I
K
Site 9
T98
L
L
E
K
E
R
K
T
K
L
Q
Y
E
K
Q
Site 10
Y147
E
K
F
T
A
I
L
Y
R
T
L
E
R
R
R
Site 11
T149
F
T
A
I
L
Y
R
T
L
E
R
R
R
L
A
Site 12
Y159
R
R
R
L
A
D
D
Y
Q
Q
K
R
W
S
W
Site 13
S165
D
Y
Q
Q
K
R
W
S
W
G
G
S
A
M
A
Site 14
S169
K
R
W
S
W
G
G
S
A
M
A
N
S
E
S
Site 15
S174
G
G
S
A
M
A
N
S
E
S
K
T
A
N
K
Site 16
S176
S
A
M
A
N
S
E
S
K
T
A
N
K
R
S
Site 17
T178
M
A
N
S
E
S
K
T
A
N
K
R
S
A
S
Site 18
S183
S
K
T
A
N
K
R
S
A
S
T
E
K
L
E
Site 19
S185
T
A
N
K
R
S
A
S
T
E
K
L
E
Q
G
Site 20
T186
A
N
K
R
S
A
S
T
E
K
L
E
Q
G
T
Site 21
S194
E
K
L
E
Q
G
T
S
A
L
I
R
Q
M
P
Site 22
S203
L
I
R
Q
M
P
L
S
S
A
G
L
Q
N
S
Site 23
S204
I
R
Q
M
P
L
S
S
A
G
L
Q
N
S
V
Site 24
S210
S
S
A
G
L
Q
N
S
V
A
K
R
K
T
D
Site 25
T216
N
S
V
A
K
R
K
T
D
K
E
R
S
S
S
Site 26
S222
K
T
D
K
E
R
S
S
S
L
N
R
R
D
S
Site 27
S223
T
D
K
E
R
S
S
S
L
N
R
R
D
S
N
Site 28
S229
S
S
L
N
R
R
D
S
N
L
H
S
S
T
D
Site 29
S233
R
R
D
S
N
L
H
S
S
T
D
K
E
Q
A
Site 30
S234
R
D
S
N
L
H
S
S
T
D
K
E
Q
A
E
Site 31
T247
A
E
R
K
P
R
V
T
G
V
T
N
Y
V
M
Site 32
Y252
R
V
T
G
V
T
N
Y
V
M
Q
Y
V
T
V
Site 33
Y256
V
T
N
Y
V
M
Q
Y
V
T
V
P
L
R
K
Site 34
T265
T
V
P
L
R
K
C
T
S
D
E
L
R
A
V
Site 35
S266
V
P
L
R
K
C
T
S
D
E
L
R
A
V
M
Site 36
S277
R
A
V
M
F
P
M
S
T
M
K
I
P
P
Q
Site 37
T285
T
M
K
I
P
P
Q
T
K
V
E
E
S
P
L
Site 38
S290
P
Q
T
K
V
E
E
S
P
L
E
K
V
E
T
Site 39
T297
S
P
L
E
K
V
E
T
P
P
K
A
S
V
D
Site 40
S302
V
E
T
P
P
K
A
S
V
D
A
P
P
Q
V
Site 41
T317
N
V
E
V
F
C
N
T
S
M
E
A
S
P
K
Site 42
S318
V
E
V
F
C
N
T
S
M
E
A
S
P
K
A
Site 43
S322
C
N
T
S
M
E
A
S
P
K
A
G
V
G
M
Site 44
S350
V
D
V
S
P
V
V
S
T
Y
D
S
E
M
S
Site 45
Y352
V
S
P
V
V
S
T
Y
D
S
E
M
S
M
D
Site 46
S354
P
V
V
S
T
Y
D
S
E
M
S
M
D
A
S
Site 47
S357
S
T
Y
D
S
E
M
S
M
D
A
S
P
E
L
Site 48
S361
S
E
M
S
M
D
A
S
P
E
L
S
I
E
A
Site 49
S429
A
E
V
A
P
K
E
S
V
K
G
S
P
K
E
Site 50
S433
P
K
E
S
V
K
G
S
P
K
E
S
M
E
A
Site 51
S437
V
K
G
S
P
K
E
S
M
E
A
S
P
E
A
Site 52
S441
P
K
E
S
M
E
A
S
P
E
A
M
V
K
A
Site 53
S449
P
E
A
M
V
K
A
S
P
K
T
S
L
E
A
Site 54
S453
V
K
A
S
P
K
T
S
L
E
A
S
M
E
A
Site 55
S457
P
K
T
S
L
E
A
S
M
E
A
S
P
K
A
Site 56
S461
L
E
A
S
M
E
A
S
P
K
A
K
A
R
D
Site 57
S473
A
R
D
A
P
K
K
S
E
M
D
K
Q
A
L
Site 58
S489
P
I
A
K
K
R
L
S
S
Y
T
E
C
Y
K
Site 59
S490
I
A
K
K
R
L
S
S
Y
T
E
C
Y
K
W
Site 60
T492
K
K
R
L
S
S
Y
T
E
C
Y
K
W
S
S
Site 61
Y495
L
S
S
Y
T
E
C
Y
K
W
S
S
S
P
E
Site 62
S500
E
C
Y
K
W
S
S
S
P
E
N
A
C
G
L
Site 63
S509
E
N
A
C
G
L
P
S
P
I
S
T
N
R
Q
Site 64
S512
C
G
L
P
S
P
I
S
T
N
R
Q
I
Q
K
Site 65
T513
G
L
P
S
P
I
S
T
N
R
Q
I
Q
K
N
Site 66
S524
I
Q
K
N
C
P
P
S
P
L
P
L
I
S
K
Site 67
S530
P
S
P
L
P
L
I
S
K
Q
S
P
Q
T
S
Site 68
S533
L
P
L
I
S
K
Q
S
P
Q
T
S
F
P
Y
Site 69
T536
I
S
K
Q
S
P
Q
T
S
F
P
Y
K
I
M
Site 70
S537
S
K
Q
S
P
Q
T
S
F
P
Y
K
I
M
P
Site 71
T548
K
I
M
P
I
Q
H
T
L
S
V
Q
S
A
S
Site 72
S550
M
P
I
Q
H
T
L
S
V
Q
S
A
S
S
T
Site 73
S556
L
S
V
Q
S
A
S
S
T
V
K
K
K
K
E
Site 74
T557
S
V
Q
S
A
S
S
T
V
K
K
K
K
E
T
Site 75
T564
T
V
K
K
K
K
E
T
V
S
K
T
T
N
R
Site 76
T568
K
K
E
T
V
S
K
T
T
N
R
C
E
A
L
Site 77
Y582
L
S
Q
R
H
M
I
Y
E
E
S
G
N
K
S
Site 78
S585
R
H
M
I
Y
E
E
S
G
N
K
S
T
A
G
Site 79
S589
Y
E
E
S
G
N
K
S
T
A
G
I
M
N
A
Site 80
T604
E
A
A
T
K
I
L
T
E
L
R
R
L
A
R
Site 81
S634
Q
Q
R
V
I
K
K
S
K
D
M
A
K
E
A
Site 82
T725
I
M
K
R
T
R
K
T
D
V
N
A
S
K
V
Site 83
S730
R
K
T
D
V
N
A
S
K
V
T
E
T
S
S
Site 84
S737
S
K
V
T
E
T
S
S
H
D
I
Y
E
E
A
Site 85
Y741
E
T
S
S
H
D
I
Y
E
E
A
E
A
D
N
Site 86
S751
A
E
A
D
N
E
E
S
D
K
D
S
L
N
E
Site 87
S755
N
E
E
S
D
K
D
S
L
N
E
M
F
P
S
Site 88
T768
P
S
A
I
L
N
G
T
G
S
P
T
K
F
K
Site 89
S770
A
I
L
N
G
T
G
S
P
T
K
F
K
M
P
Site 90
S796
V
F
L
E
D
G
T
S
Q
V
R
K
E
P
K
Site 91
T804
Q
V
R
K
E
P
K
T
Y
F
N
G
D
L
K
Site 92
Y805
V
R
K
E
P
K
T
Y
F
N
G
D
L
K
N
Site 93
S817
L
K
N
F
R
Q
K
S
M
K
D
T
S
I
Q
Site 94
T821
R
Q
K
S
M
K
D
T
S
I
Q
E
V
V
S
Site 95
S828
T
S
I
Q
E
V
V
S
R
P
S
S
K
R
M
Site 96
S831
Q
E
V
V
S
R
P
S
S
K
R
M
T
S
H
Site 97
S832
E
V
V
S
R
P
S
S
K
R
M
T
S
H
T
Site 98
T836
R
P
S
S
K
R
M
T
S
H
T
T
K
T
R
Site 99
S837
P
S
S
K
R
M
T
S
H
T
T
K
T
R
K
Site 100
T839
S
K
R
M
T
S
H
T
T
K
T
R
K
A
D
Site 101
T848
K
T
R
K
A
D
E
T
N
T
T
S
R
S
S
Site 102
T850
R
K
A
D
E
T
N
T
T
S
R
S
S
A
Q
Site 103
T851
K
A
D
E
T
N
T
T
S
R
S
S
A
Q
T
Site 104
S852
A
D
E
T
N
T
T
S
R
S
S
A
Q
T
K
Site 105
S854
E
T
N
T
T
S
R
S
S
A
Q
T
K
S
E
Site 106
S855
T
N
T
T
S
R
S
S
A
Q
T
K
S
E
G
Site 107
T858
T
S
R
S
S
A
Q
T
K
S
E
G
F
H
D
Site 108
S860
R
S
S
A
Q
T
K
S
E
G
F
H
D
I
L
Site 109
S870
F
H
D
I
L
P
K
S
S
D
T
F
R
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation