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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Fam116a
Full Name:
Protein FAM116A
Alias:
Family with sequence similarity 116, member a; Flj34969
Type:
Mass (Da):
69556
Number AA:
608
UniProt ID:
Q8IWF6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
P
A
G
L
G
P
G
S
R
R
P
L
D
E
A
Site 2
Y82
G
Q
A
V
E
V
I
Y
P
Q
H
S
K
L
T
Site 3
T89
Y
P
Q
H
S
K
L
T
D
R
E
K
T
N
I
Site 4
T94
K
L
T
D
R
E
K
T
N
I
C
Y
L
S
F
Site 5
Y98
R
E
K
T
N
I
C
Y
L
S
F
P
D
S
N
Site 6
S100
K
T
N
I
C
Y
L
S
F
P
D
S
N
S
G
Site 7
S104
C
Y
L
S
F
P
D
S
N
S
G
C
L
G
D
Site 8
S106
L
S
F
P
D
S
N
S
G
C
L
G
D
T
Q
Site 9
S121
F
C
F
R
F
R
Q
S
S
G
R
R
V
S
L
Site 10
S122
C
F
R
F
R
Q
S
S
G
R
R
V
S
L
H
Site 11
S127
Q
S
S
G
R
R
V
S
L
H
C
L
L
D
Q
Site 12
Y142
F
D
K
D
L
P
V
Y
L
K
K
D
P
A
Y
Site 13
Y149
Y
L
K
K
D
P
A
Y
F
Y
G
Y
V
Y
F
Site 14
Y151
K
K
D
P
A
Y
F
Y
G
Y
V
Y
F
R
Q
Site 15
Y153
D
P
A
Y
F
Y
G
Y
V
Y
F
R
Q
V
R
Site 16
Y155
A
Y
F
Y
G
Y
V
Y
F
R
Q
V
R
D
K
Site 17
T163
F
R
Q
V
R
D
K
T
L
K
R
G
Y
F
Q
Site 18
Y168
D
K
T
L
K
R
G
Y
F
Q
K
S
L
V
L
Site 19
S172
K
R
G
Y
F
Q
K
S
L
V
L
I
S
K
L
Site 20
Y196
L
K
Q
I
A
P
E
Y
F
E
K
N
E
P
Y
Site 21
Y203
Y
F
E
K
N
E
P
Y
L
E
A
A
C
N
D
Site 22
T238
V
M
K
V
R
I
P
T
C
H
D
K
P
G
T
Site 23
S301
P
L
V
V
M
A
P
S
P
S
E
S
S
E
T
Site 24
S305
M
A
P
S
P
S
E
S
S
E
T
V
L
A
L
Site 25
Y321
N
C
I
S
P
L
K
Y
F
S
D
F
R
P
Y
Site 26
S323
I
S
P
L
K
Y
F
S
D
F
R
P
Y
F
T
Site 27
Y328
Y
F
S
D
F
R
P
Y
F
T
I
H
D
S
E
Site 28
T330
S
D
F
R
P
Y
F
T
I
H
D
S
E
F
K
Site 29
Y339
H
D
S
E
F
K
E
Y
T
T
R
T
Q
A
P
Site 30
T343
F
K
E
Y
T
T
R
T
Q
A
P
P
S
V
I
Site 31
S348
T
R
T
Q
A
P
P
S
V
I
L
G
V
T
N
Site 32
T394
K
K
L
K
N
L
K
T
L
D
S
K
P
G
V
Site 33
S397
K
N
L
K
T
L
D
S
K
P
G
V
Y
T
S
Site 34
Y402
L
D
S
K
P
G
V
Y
T
S
Y
K
P
Y
L
Site 35
S404
S
K
P
G
V
Y
T
S
Y
K
P
Y
L
N
R
Site 36
Y408
V
Y
T
S
Y
K
P
Y
L
N
R
D
E
E
I
Site 37
S429
G
V
Q
Q
K
R
P
S
E
A
Q
S
V
I
L
Site 38
S433
K
R
P
S
E
A
Q
S
V
I
L
R
R
Y
F
Site 39
Y439
Q
S
V
I
L
R
R
Y
F
L
E
L
T
Q
S
Site 40
S457
P
L
E
R
Y
V
A
S
L
M
P
L
Q
K
S
Site 41
S464
S
L
M
P
L
Q
K
S
I
S
P
W
K
S
P
Site 42
S466
M
P
L
Q
K
S
I
S
P
W
K
S
P
P
Q
Site 43
S470
K
S
I
S
P
W
K
S
P
P
Q
L
R
Q
F
Site 44
T485
L
P
E
E
F
M
K
T
L
E
K
T
G
P
Q
Site 45
T494
E
K
T
G
P
Q
L
T
S
R
I
K
G
D
W
Site 46
Y505
K
G
D
W
I
G
L
Y
R
H
F
L
K
S
P
Site 47
T526
K
T
R
R
K
E
M
T
Q
K
L
E
A
L
H
Site 48
T579
H
L
P
V
K
P
D
T
M
E
K
L
R
T
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation