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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC83
Full Name:
Coiled-coil domain-containing protein 83
Alias:
CCD83; coiled-coil domain containing 83; FLJ42119; MGC34732
Type:
Mass (Da):
48832
Number AA:
413
UniProt ID:
Q8IWF9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
G
K
A
N
K
K
D
T
H
D
G
P
P
K
E
Site 2
S25
K
E
I
K
L
P
T
S
E
A
L
L
D
Y
Q
Site 3
Y31
T
S
E
A
L
L
D
Y
Q
C
Q
I
K
E
D
Site 4
T49
Q
F
M
F
Q
I
K
T
L
R
K
K
N
Q
K
Site 5
Y57
L
R
K
K
N
Q
K
Y
H
E
R
N
S
R
L
Site 6
S62
Q
K
Y
H
E
R
N
S
R
L
K
E
E
Q
I
Site 7
S80
R
H
L
L
K
E
L
S
E
E
K
A
E
G
L
Site 8
S132
K
L
F
L
E
K
L
S
E
K
E
Y
W
E
E
Site 9
Y136
E
K
L
S
E
K
E
Y
W
E
E
Y
K
N
V
Site 10
Y140
E
K
E
Y
W
E
E
Y
K
N
V
G
S
E
R
Site 11
S145
E
E
Y
K
N
V
G
S
E
R
H
A
K
L
I
Site 12
T153
E
R
H
A
K
L
I
T
S
L
Q
N
D
I
N
Site 13
T161
S
L
Q
N
D
I
N
T
V
K
E
N
A
E
K
Site 14
Y173
A
E
K
M
S
E
H
Y
K
I
T
L
E
D
T
Site 15
T176
M
S
E
H
Y
K
I
T
L
E
D
T
R
K
K
Site 16
S211
V
K
L
I
D
K
G
S
Y
L
E
I
W
E
N
Site 17
Y212
K
L
I
D
K
G
S
Y
L
E
I
W
E
N
D
Site 18
S283
E
V
P
P
E
E
M
S
L
E
L
P
E
T
H
Site 19
T289
M
S
L
E
L
P
E
T
H
I
E
E
K
S
E
Site 20
S295
E
T
H
I
E
E
K
S
E
L
Q
P
T
E
V
Site 21
T300
E
K
S
E
L
Q
P
T
E
V
E
S
R
D
L
Site 22
S304
L
Q
P
T
E
V
E
S
R
D
L
M
S
S
S
Site 23
S309
V
E
S
R
D
L
M
S
S
S
D
E
S
T
I
Site 24
S310
E
S
R
D
L
M
S
S
S
D
E
S
T
I
L
Site 25
S311
S
R
D
L
M
S
S
S
D
E
S
T
I
L
H
Site 26
S314
L
M
S
S
S
D
E
S
T
I
L
H
L
S
H
Site 27
T315
M
S
S
S
D
E
S
T
I
L
H
L
S
H
E
Site 28
S320
E
S
T
I
L
H
L
S
H
E
N
S
I
E
D
Site 29
S324
L
H
L
S
H
E
N
S
I
E
D
L
Q
Y
V
Site 30
Y330
N
S
I
E
D
L
Q
Y
V
K
I
D
K
E
E
Site 31
S339
K
I
D
K
E
E
N
S
G
T
E
F
G
D
T
Site 32
T341
D
K
E
E
N
S
G
T
E
F
G
D
T
D
M
Site 33
T346
S
G
T
E
F
G
D
T
D
M
K
Y
L
L
Y
Site 34
Y350
F
G
D
T
D
M
K
Y
L
L
Y
E
D
E
K
Site 35
Y353
T
D
M
K
Y
L
L
Y
E
D
E
K
D
F
K
Site 36
Y362
D
E
K
D
F
K
D
Y
V
N
L
G
P
L
G
Site 37
S374
P
L
G
V
K
L
M
S
V
E
S
K
K
M
P
Site 38
S377
V
K
L
M
S
V
E
S
K
K
M
P
I
H
F
Site 39
Y394
K
E
I
P
V
K
L
Y
K
D
V
R
S
P
E
Site 40
S399
K
L
Y
K
D
V
R
S
P
E
S
H
I
T
Y
Site 41
S402
K
D
V
R
S
P
E
S
H
I
T
Y
K
M
M
Site 42
T405
R
S
P
E
S
H
I
T
Y
K
M
M
K
S
F
Site 43
Y406
S
P
E
S
H
I
T
Y
K
M
M
K
S
F
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation