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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZC3H7A
Full Name:
Zinc finger CCCH domain-containing protein 7A
Alias:
FLJ10027; FLJ20318; HSPC055; Z3H7A; ZC3H7; ZC3HDC7; zinc finger CCCH-type containing 7A; zinc-finger protein AY163807
Type:
Unknown function
Mass (Da):
110538
Number AA:
971
UniProt ID:
Q8IWR0
International Prot ID:
IPI00217355
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0008270
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
E
G
L
Q
F
I
Q
S
P
L
S
Y
P
G
T
Site 2
S27
Q
F
I
Q
S
P
L
S
Y
P
G
T
Q
E
Q
Site 3
Y28
F
I
Q
S
P
L
S
Y
P
G
T
Q
E
Q
Y
Site 4
T31
S
P
L
S
Y
P
G
T
Q
E
Q
Y
A
V
Y
Site 5
Y38
T
Q
E
Q
Y
A
V
Y
L
R
A
L
V
R
N
Site 6
Y54
F
N
E
G
N
D
V
Y
R
E
H
D
W
N
N
Site 7
Y66
W
N
N
S
I
S
Q
Y
T
E
A
L
N
I
A
Site 8
Y75
E
A
L
N
I
A
D
Y
A
K
S
E
E
I
L
Site 9
S78
N
I
A
D
Y
A
K
S
E
E
I
L
I
P
K
Site 10
Y92
K
E
I
I
E
K
L
Y
I
N
R
I
A
C
Y
Site 11
S117
E
D
C
N
I
V
L
S
L
N
A
S
N
C
K
Site 12
S130
C
K
A
L
Y
R
K
S
K
A
L
S
D
L
G
Site 13
S134
Y
R
K
S
K
A
L
S
D
L
G
R
Y
K
K
Site 14
Y143
L
G
R
Y
K
K
A
Y
D
A
V
A
K
C
S
Site 15
Y178
G
F
K
I
R
K
A
Y
V
R
A
E
L
S
L
Site 16
S184
A
Y
V
R
A
E
L
S
L
K
S
V
P
G
D
Site 17
S187
R
A
E
L
S
L
K
S
V
P
G
D
G
A
T
Site 18
S200
A
T
K
A
L
N
H
S
V
E
D
I
E
P
D
Site 19
T210
D
I
E
P
D
L
L
T
P
R
Q
E
A
V
P
Site 20
S227
S
L
P
A
P
S
F
S
H
E
V
G
S
E
L
Site 21
T269
N
G
G
K
M
P
F
T
M
P
E
A
F
L
D
Site 22
S292
E
L
D
D
L
L
D
S
A
P
E
T
N
E
T
Site 23
T296
L
L
D
S
A
P
E
T
N
E
T
V
M
P
S
Site 24
T299
S
A
P
E
T
N
E
T
V
M
P
S
A
L
V
Site 25
S314
R
G
P
L
Q
T
A
S
V
S
P
S
M
P
F
Site 26
S318
Q
T
A
S
V
S
P
S
M
P
F
S
A
S
L
Site 27
Y335
T
L
P
I
G
A
R
Y
A
P
P
P
S
F
S
Site 28
S340
A
R
Y
A
P
P
P
S
F
S
E
F
Y
P
P
Site 29
S342
Y
A
P
P
P
S
F
S
E
F
Y
P
P
L
T
Site 30
Y345
P
P
S
F
S
E
F
Y
P
P
L
T
S
S
L
Site 31
T349
S
E
F
Y
P
P
L
T
S
S
L
E
D
F
C
Site 32
S351
F
Y
P
P
L
T
S
S
L
E
D
F
C
S
S
Site 33
S357
S
S
L
E
D
F
C
S
S
L
N
S
F
S
M
Site 34
S358
S
L
E
D
F
C
S
S
L
N
S
F
S
M
S
Site 35
S361
D
F
C
S
S
L
N
S
F
S
M
S
E
S
K
Site 36
S363
C
S
S
L
N
S
F
S
M
S
E
S
K
R
D
Site 37
S365
S
L
N
S
F
S
M
S
E
S
K
R
D
L
S
Site 38
S367
N
S
F
S
M
S
E
S
K
R
D
L
S
T
S
Site 39
S372
S
E
S
K
R
D
L
S
T
S
T
S
R
E
G
Site 40
S374
S
K
R
D
L
S
T
S
T
S
R
E
G
T
P
Site 41
S376
R
D
L
S
T
S
T
S
R
E
G
T
P
L
N
Site 42
T380
T
S
T
S
R
E
G
T
P
L
N
N
S
N
S
Site 43
S385
E
G
T
P
L
N
N
S
N
S
S
L
L
L
M
Site 44
S387
T
P
L
N
N
S
N
S
S
L
L
L
M
N
G
Site 45
S409
E
N
F
L
G
I
S
S
Q
P
R
N
D
F
G
Site 46
S421
D
F
G
N
F
F
G
S
A
V
T
K
P
S
S
Site 47
T424
N
F
F
G
S
A
V
T
K
P
S
S
S
V
T
Site 48
S427
G
S
A
V
T
K
P
S
S
S
V
T
P
R
H
Site 49
S428
S
A
V
T
K
P
S
S
S
V
T
P
R
H
P
Site 50
S429
A
V
T
K
P
S
S
S
V
T
P
R
H
P
L
Site 51
T431
T
K
P
S
S
S
V
T
P
R
H
P
L
E
G
Site 52
Y462
P
K
L
M
D
F
T
Y
H
A
N
I
D
H
K
Site 53
S486
I
K
N
V
E
D
K
S
W
K
K
I
R
P
R
Site 54
T495
K
K
I
R
P
R
P
T
K
T
N
Y
E
G
P
Site 55
T497
I
R
P
R
P
T
K
T
N
Y
E
G
P
Y
Y
Site 56
Y499
P
R
P
T
K
T
N
Y
E
G
P
Y
Y
I
C
Site 57
Y504
T
N
Y
E
G
P
Y
Y
I
C
K
D
V
A
A
Site 58
Y517
A
A
E
E
E
C
R
Y
S
G
H
C
T
F
A
Site 59
Y525
S
G
H
C
T
F
A
Y
C
Q
E
E
I
D
V
Site 60
T534
Q
E
E
I
D
V
W
T
L
E
R
K
G
A
F
Site 61
S542
L
E
R
K
G
A
F
S
R
E
A
F
F
G
G
Site 62
T556
G
N
G
K
I
N
L
T
V
F
K
L
L
Q
E
Site 63
S584
D
H
K
P
R
M
I
S
K
R
N
K
D
N
S
Site 64
S591
S
K
R
N
K
D
N
S
T
A
C
S
H
P
V
Site 65
T592
K
R
N
K
D
N
S
T
A
C
S
H
P
V
T
Site 66
S595
K
D
N
S
T
A
C
S
H
P
V
T
K
H
E
Site 67
T599
T
A
C
S
H
P
V
T
K
H
E
F
E
D
N
Site 68
T617
V
H
I
L
R
E
T
T
V
K
Y
S
K
I
R
Site 69
Y620
L
R
E
T
T
V
K
Y
S
K
I
R
S
F
H
Site 70
S621
R
E
T
T
V
K
Y
S
K
I
R
S
F
H
G
Site 71
S625
V
K
Y
S
K
I
R
S
F
H
G
Q
C
Q
L
Site 72
Y641
L
C
R
H
E
V
R
Y
G
C
L
R
E
D
E
Site 73
Y681
I
A
Q
E
S
K
R
Y
W
Q
N
L
E
A
N
Site 74
Y730
E
P
D
K
N
R
K
Y
C
S
A
K
A
R
H
Site 75
S738
C
S
A
K
A
R
H
S
W
T
K
D
R
R
A
Site 76
S750
R
R
A
M
R
V
M
S
I
E
R
K
K
W
M
Site 77
Y786
A
S
G
K
K
C
Q
Y
V
G
N
C
S
F
A
Site 78
S795
G
N
C
S
F
A
H
S
P
E
E
R
E
V
W
Site 79
Y804
E
E
R
E
V
W
T
Y
M
K
E
N
G
I
Q
Site 80
S823
F
Y
E
L
W
L
K
S
Q
K
N
E
K
S
E
Site 81
S829
K
S
Q
K
N
E
K
S
E
D
I
A
S
Q
S
Site 82
S834
E
K
S
E
D
I
A
S
Q
S
N
K
E
N
G
Site 83
S836
S
E
D
I
A
S
Q
S
N
K
E
N
G
K
Q
Site 84
Y850
Q
I
H
M
P
T
D
Y
A
E
V
T
V
D
F
Site 85
S878
Q
W
Q
G
H
I
S
S
E
K
H
K
E
K
V
Site 86
Y893
F
H
T
E
D
D
Q
Y
C
W
Q
H
R
F
P
Site 87
Y903
Q
H
R
F
P
T
G
Y
F
S
I
C
D
R
Y
Site 88
S964
D
N
D
F
G
K
Y
S
F
L
F
K
D
L
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation