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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PHF6
Full Name:
PHD finger protein 6
Alias:
KIAA1823; PHD-like zinc fnger protein
Type:
Uncharacterized protein
Mass (Da):
41290
Number AA:
365
UniProt ID:
Q8IWS0
International Prot ID:
IPI00395568
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005730
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S34
E
C
G
Q
L
L
I
S
E
N
Q
K
V
A
A
Site 2
S54
L
F
S
S
A
L
V
S
S
H
S
D
N
E
S
Site 3
S55
F
S
S
A
L
V
S
S
H
S
D
N
E
S
L
Site 4
S57
S
A
L
V
S
S
H
S
D
N
E
S
L
G
G
Site 5
S61
S
S
H
S
D
N
E
S
L
G
G
F
S
I
E
Site 6
T78
Q
K
E
I
K
R
G
T
K
L
M
C
S
L
C
Site 7
S120
A
Q
I
R
E
K
P
S
Q
G
I
Y
M
V
Y
Site 8
Y124
E
K
P
S
Q
G
I
Y
M
V
Y
C
R
K
H
Site 9
Y127
S
Q
G
I
Y
M
V
Y
C
R
K
H
K
K
T
Site 10
T134
Y
C
R
K
H
K
K
T
A
H
N
S
E
A
D
Site 11
S138
H
K
K
T
A
H
N
S
E
A
D
L
E
E
S
Site 12
S145
S
E
A
D
L
E
E
S
F
N
E
H
E
L
E
Site 13
S154
N
E
H
E
L
E
P
S
S
P
K
S
K
K
K
Site 14
S155
E
H
E
L
E
P
S
S
P
K
S
K
K
K
S
Site 15
S158
L
E
P
S
S
P
K
S
K
K
K
S
R
K
G
Site 16
S162
S
P
K
S
K
K
K
S
R
K
G
R
P
R
K
Site 17
T170
R
K
G
R
P
R
K
T
N
F
K
G
L
S
E
Site 18
S176
K
T
N
F
K
G
L
S
E
D
T
R
S
T
S
Site 19
T179
F
K
G
L
S
E
D
T
R
S
T
S
S
H
G
Site 20
S181
G
L
S
E
D
T
R
S
T
S
S
H
G
T
D
Site 21
T182
L
S
E
D
T
R
S
T
S
S
H
G
T
D
E
Site 22
S183
S
E
D
T
R
S
T
S
S
H
G
T
D
E
M
Site 23
T187
R
S
T
S
S
H
G
T
D
E
M
E
S
S
S
Site 24
S193
G
T
D
E
M
E
S
S
S
Y
R
D
R
S
P
Site 25
S194
T
D
E
M
E
S
S
S
Y
R
D
R
S
P
H
Site 26
Y195
D
E
M
E
S
S
S
Y
R
D
R
S
P
H
R
Site 27
S199
S
S
S
Y
R
D
R
S
P
H
R
S
S
P
S
Site 28
S203
R
D
R
S
P
H
R
S
S
P
S
D
T
R
P
Site 29
S204
D
R
S
P
H
R
S
S
P
S
D
T
R
P
K
Site 30
S206
S
P
H
R
S
S
P
S
D
T
R
P
K
C
G
Site 31
T208
H
R
S
S
P
S
D
T
R
P
K
C
G
F
C
Site 32
S247
Y
K
C
M
L
F
S
S
G
T
V
Q
L
T
T
Site 33
T253
S
S
G
T
V
Q
L
T
T
T
S
R
A
E
F
Site 34
T254
S
G
T
V
Q
L
T
T
T
S
R
A
E
F
G
Site 35
T255
G
T
V
Q
L
T
T
T
S
R
A
E
F
G
D
Site 36
T267
F
G
D
F
D
I
K
T
V
L
Q
E
I
K
R
Site 37
T281
R
G
K
R
M
K
C
T
L
C
S
Q
P
G
A
Site 38
S284
R
M
K
C
T
L
C
S
Q
P
G
A
T
I
G
Site 39
Y303
A
C
V
K
T
Y
H
Y
H
C
G
V
Q
D
K
Site 40
Y313
G
V
Q
D
K
A
K
Y
I
E
N
M
S
R
G
Site 41
Y322
E
N
M
S
R
G
I
Y
K
L
Y
C
K
N
H
Site 42
Y325
S
R
G
I
Y
K
L
Y
C
K
N
H
S
G
N
Site 43
S344
E
E
D
E
E
R
E
S
K
S
R
G
K
V
E
Site 44
S346
D
E
E
R
E
S
K
S
R
G
K
V
E
I
D
Site 45
T358
E
I
D
Q
Q
Q
L
T
Q
Q
Q
L
N
G
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation