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Updated November 2019
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Protein Info
Short Name:
SULF1
Full Name:
Extracellular sulfatase Sulf-1
Alias:
Type:
Mass (Da):
101027
Number AA:
871
UniProt ID:
Q8IWU6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T24
L
L
G
S
L
C
S
T
V
R
S
P
R
F
R
Site 2
S27
S
L
C
S
T
V
R
S
P
R
F
R
G
R
I
Site 3
S59
D
Q
D
V
E
L
G
S
L
Q
V
M
N
K
T
Site 4
T66
S
L
Q
V
M
N
K
T
R
K
I
M
E
H
G
Site 5
S90
T
T
P
M
C
C
P
S
R
S
S
M
L
T
G
Site 6
S92
P
M
C
C
P
S
R
S
S
M
L
T
G
K
Y
Site 7
T96
P
S
R
S
S
M
L
T
G
K
Y
V
H
N
H
Site 8
Y99
S
S
M
L
T
G
K
Y
V
H
N
H
N
V
Y
Site 9
T125
Q
A
M
H
E
P
R
T
F
A
V
Y
L
N
N
Site 10
Y129
E
P
R
T
F
A
V
Y
L
N
N
T
G
Y
R
Site 11
Y135
V
Y
L
N
N
T
G
Y
R
T
A
F
F
G
K
Site 12
Y143
R
T
A
F
F
G
K
Y
L
N
E
Y
N
G
S
Site 13
Y147
F
G
K
Y
L
N
E
Y
N
G
S
Y
I
P
P
Site 14
Y151
L
N
E
Y
N
G
S
Y
I
P
P
G
W
R
E
Site 15
Y169
L
I
K
N
S
R
F
Y
N
Y
T
V
C
R
N
Site 16
Y171
K
N
S
R
F
Y
N
Y
T
V
C
R
N
G
I
Site 17
Y186
K
E
K
H
G
F
D
Y
A
K
D
Y
F
T
D
Site 18
Y190
G
F
D
Y
A
K
D
Y
F
T
D
L
I
T
N
Site 19
Y202
I
T
N
E
S
I
N
Y
F
K
M
S
K
R
M
Site 20
S230
A
P
H
G
P
E
D
S
A
P
Q
F
S
K
L
Site 21
Y238
A
P
Q
F
S
K
L
Y
P
N
A
S
Q
H
I
Site 22
S242
S
K
L
Y
P
N
A
S
Q
H
I
T
P
S
Y
Site 23
T246
P
N
A
S
Q
H
I
T
P
S
Y
N
Y
A
P
Site 24
Y249
S
Q
H
I
T
P
S
Y
N
Y
A
P
N
M
D
Site 25
T285
L
Q
R
K
R
L
Q
T
L
M
S
V
D
D
S
Site 26
S288
K
R
L
Q
T
L
M
S
V
D
D
S
V
E
R
Site 27
S292
T
L
M
S
V
D
D
S
V
E
R
L
Y
N
M
Site 28
Y297
D
D
S
V
E
R
L
Y
N
M
L
V
E
T
G
Site 29
T309
E
T
G
E
L
E
N
T
Y
I
I
Y
T
A
D
Site 30
Y310
T
G
E
L
E
N
T
Y
I
I
Y
T
A
D
H
Site 31
Y313
L
E
N
T
Y
I
I
Y
T
A
D
H
G
Y
H
Site 32
Y319
I
Y
T
A
D
H
G
Y
H
I
G
Q
F
G
L
Site 33
S331
F
G
L
V
K
G
K
S
M
P
Y
D
F
D
I
Site 34
T376
L
D
I
A
G
L
D
T
P
P
D
V
D
G
K
Site 35
S384
P
P
D
V
D
G
K
S
V
L
K
L
L
D
P
Site 36
T400
K
P
G
N
R
F
R
T
N
K
K
A
K
I
W
Site 37
T410
K
A
K
I
W
R
D
T
F
L
V
E
R
G
K
Site 38
S425
F
L
R
K
K
E
E
S
S
K
N
I
Q
Q
S
Site 39
S432
S
S
K
N
I
Q
Q
S
N
H
L
P
K
Y
E
Site 40
Y438
Q
S
N
H
L
P
K
Y
E
R
V
K
E
L
C
Site 41
T484
K
G
P
S
D
L
L
T
V
R
Q
S
T
R
N
Site 42
S488
D
L
L
T
V
R
Q
S
T
R
N
L
Y
A
R
Site 43
T489
L
L
T
V
R
Q
S
T
R
N
L
Y
A
R
G
Site 44
Y493
R
Q
S
T
R
N
L
Y
A
R
G
F
H
D
K
Site 45
S505
H
D
K
D
K
E
C
S
C
R
E
S
G
Y
R
Site 46
S509
K
E
C
S
C
R
E
S
G
Y
R
A
S
R
S
Site 47
S514
R
E
S
G
Y
R
A
S
R
S
Q
R
K
S
Q
Site 48
S516
S
G
Y
R
A
S
R
S
Q
R
K
S
Q
R
Q
Site 49
S520
A
S
R
S
Q
R
K
S
Q
R
Q
F
L
R
N
Site 50
T530
Q
F
L
R
N
Q
G
T
P
K
Y
K
P
R
F
Site 51
Y533
R
N
Q
G
T
P
K
Y
K
P
R
F
V
H
T
Site 52
T543
R
F
V
H
T
R
Q
T
R
S
L
S
V
E
F
Site 53
S545
V
H
T
R
Q
T
R
S
L
S
V
E
F
E
G
Site 54
S547
T
R
Q
T
R
S
L
S
V
E
F
E
G
E
I
Site 55
Y555
V
E
F
E
G
E
I
Y
D
I
N
L
E
E
E
Site 56
S590
G
P
R
D
L
Q
A
S
S
G
G
N
R
G
R
Site 57
S602
R
G
R
M
L
A
D
S
S
N
A
V
G
P
P
Site 58
S603
G
R
M
L
A
D
S
S
N
A
V
G
P
P
T
Site 59
T610
S
N
A
V
G
P
P
T
T
V
R
V
T
H
K
Site 60
T611
N
A
V
G
P
P
T
T
V
R
V
T
H
K
C
Site 61
Y633
I
H
C
E
R
E
L
Y
Q
S
A
R
A
W
K
Site 62
S676
R
R
K
P
E
E
C
S
C
S
K
Q
S
Y
Y
Site 63
S678
K
P
E
E
C
S
C
S
K
Q
S
Y
Y
N
K
Site 64
Y682
C
S
C
S
K
Q
S
Y
Y
N
K
E
K
G
V
Site 65
Y683
S
C
S
K
Q
S
Y
Y
N
K
E
K
G
V
K
Site 66
S697
K
K
Q
E
K
L
K
S
H
L
H
P
F
K
E
Site 67
S740
Q
R
K
G
E
E
C
S
L
P
G
L
T
C
F
Site 68
Y776
T
S
S
N
N
N
T
Y
W
C
L
R
T
V
N
Site 69
Y800
F
A
T
G
F
L
E
Y
F
D
M
N
T
D
P
Site 70
Y808
F
D
M
N
T
D
P
Y
Q
L
T
N
T
V
H
Site 71
T813
D
P
Y
Q
L
T
N
T
V
H
T
V
E
R
G
Site 72
Y838
E
L
R
S
C
Q
G
Y
K
Q
C
N
P
R
P
Site 73
S857
V
G
N
K
D
G
G
S
Y
D
L
H
R
G
Q
Site 74
Y858
G
N
K
D
G
G
S
Y
D
L
H
R
G
Q
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation