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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LAX1
Full Name:
Lymphocyte transmembrane adapter 1
Alias:
FLJ20340; LAT-like membrane associated protein; LAX; Linker for activation of X cells; Lymphocyte transmembrane adaptor 1; Membrane-associated adapter protein LAX
Type:
Adaptor/scaffold
Mass (Da):
44085
Number AA:
398
UniProt ID:
Q8IWV1
International Prot ID:
IPI00301971
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0042169
GO:0019901
PhosphoSite+
KinaseNET
Biological Process:
GO:0042113
GO:0000188
GO:0050868
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
D
G
V
T
P
T
L
S
T
I
R
G
R
T
L
Site 2
T10
G
V
T
P
T
L
S
T
I
R
G
R
T
L
E
Site 3
T15
L
S
T
I
R
G
R
T
L
E
S
S
T
L
H
Site 4
S19
R
G
R
T
L
E
S
S
T
L
H
V
T
P
R
Site 5
T20
G
R
T
L
E
S
S
T
L
H
V
T
P
R
S
Site 6
T24
E
S
S
T
L
H
V
T
P
R
S
L
D
R
N
Site 7
S27
T
L
H
V
T
P
R
S
L
D
R
N
K
D
Q
Site 8
T36
D
R
N
K
D
Q
I
T
N
I
F
S
G
F
A
Site 9
Y71
R
K
K
R
Q
V
P
Y
L
R
V
T
V
M
P
Site 10
T81
V
T
V
M
P
L
L
T
L
P
Q
T
R
Q
R
Site 11
T85
P
L
L
T
L
P
Q
T
R
Q
R
A
K
N
I
Site 12
Y93
R
Q
R
A
K
N
I
Y
D
I
L
P
W
R
Q
Site 13
S108
E
D
L
G
R
H
E
S
R
S
M
R
I
F
S
Site 14
S110
L
G
R
H
E
S
R
S
M
R
I
F
S
T
E
Site 15
S115
S
R
S
M
R
I
F
S
T
E
S
L
L
S
R
Site 16
T116
R
S
M
R
I
F
S
T
E
S
L
L
S
R
N
Site 17
S118
M
R
I
F
S
T
E
S
L
L
S
R
N
S
E
Site 18
S121
F
S
T
E
S
L
L
S
R
N
S
E
S
P
E
Site 19
S124
E
S
L
L
S
R
N
S
E
S
P
E
H
V
P
Site 20
S126
L
L
S
R
N
S
E
S
P
E
H
V
P
S
Q
Site 21
S132
E
S
P
E
H
V
P
S
Q
A
G
N
A
F
Q
Site 22
Y150
A
H
I
H
A
T
E
Y
A
V
G
I
Y
D
N
Site 23
S179
H
C
I
N
V
R
A
S
R
D
C
A
S
I
S
Site 24
S184
R
A
S
R
D
C
A
S
I
S
S
E
D
S
H
Site 25
S186
S
R
D
C
A
S
I
S
S
E
D
S
H
D
Y
Site 26
S187
R
D
C
A
S
I
S
S
E
D
S
H
D
Y
V
Site 27
S190
A
S
I
S
S
E
D
S
H
D
Y
V
N
V
P
Site 28
Y193
S
S
E
D
S
H
D
Y
V
N
V
P
T
A
E
Site 29
T205
T
A
E
E
I
A
E
T
L
A
S
T
K
S
P
Site 30
S208
E
I
A
E
T
L
A
S
T
K
S
P
S
R
N
Site 31
T209
I
A
E
T
L
A
S
T
K
S
P
S
R
N
L
Site 32
S211
E
T
L
A
S
T
K
S
P
S
R
N
L
F
V
Site 33
S221
R
N
L
F
V
L
P
S
T
Q
K
L
E
F
T
Site 34
T242
C
G
D
A
G
D
C
T
S
L
Y
S
P
G
A
Site 35
S243
G
D
A
G
D
C
T
S
L
Y
S
P
G
A
E
Site 36
Y245
A
G
D
C
T
S
L
Y
S
P
G
A
E
D
S
Site 37
S246
G
D
C
T
S
L
Y
S
P
G
A
E
D
S
D
Site 38
S252
Y
S
P
G
A
E
D
S
D
S
L
S
N
G
E
Site 39
S254
P
G
A
E
D
S
D
S
L
S
N
G
E
G
S
Site 40
S256
A
E
D
S
D
S
L
S
N
G
E
G
S
S
Q
Site 41
S262
L
S
N
G
E
G
S
S
Q
I
S
N
D
Y
V
Site 42
S265
G
E
G
S
S
Q
I
S
N
D
Y
V
N
M
T
Site 43
Y268
S
S
Q
I
S
N
D
Y
V
N
M
T
G
L
D
Site 44
S277
N
M
T
G
L
D
L
S
A
I
Q
E
R
Q
L
Site 45
Y294
A
F
Q
C
C
R
D
Y
E
N
V
P
A
A
D
Site 46
S303
N
V
P
A
A
D
P
S
G
S
Q
Q
Q
A
E
Site 47
S316
A
E
K
D
V
P
S
S
N
I
G
H
V
E
D
Site 48
T325
I
G
H
V
E
D
K
T
D
D
P
G
T
H
V
Site 49
T330
D
K
T
D
D
P
G
T
H
V
Q
C
V
K
R
Site 50
T338
H
V
Q
C
V
K
R
T
F
L
A
S
G
D
Y
Site 51
S342
V
K
R
T
F
L
A
S
G
D
Y
A
D
F
Q
Site 52
Y345
T
F
L
A
S
G
D
Y
A
D
F
Q
P
F
T
Site 53
T352
Y
A
D
F
Q
P
F
T
Q
S
E
D
S
Q
M
Site 54
S357
P
F
T
Q
S
E
D
S
Q
M
K
H
R
E
E
Site 55
S366
M
K
H
R
E
E
M
S
N
E
D
S
S
D
Y
Site 56
S370
E
E
M
S
N
E
D
S
S
D
Y
E
N
V
L
Site 57
S371
E
M
S
N
E
D
S
S
D
Y
E
N
V
L
T
Site 58
Y373
S
N
E
D
S
S
D
Y
E
N
V
L
T
A
K
Site 59
T378
S
D
Y
E
N
V
L
T
A
K
L
G
G
R
D
Site 60
S386
A
K
L
G
G
R
D
S
E
Q
G
P
G
T
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation