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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CNTN4
Full Name:
Contactin-4
Alias:
Brain-derived immunoglobulin superfamily protein 2
Type:
Mass (Da):
113454
Number AA:
1026
UniProt ID:
Q8IWV2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S41
P
V
M
F
P
L
D
S
E
E
K
K
V
K
L
Site 2
T71
L
N
G
T
D
V
D
T
G
M
D
F
R
Y
S
Site 3
Y77
D
T
G
M
D
F
R
Y
S
V
V
E
G
S
L
Site 4
T92
L
I
N
N
P
N
K
T
Q
D
A
G
T
Y
Q
Site 5
S105
Y
Q
C
T
A
T
N
S
F
G
T
I
V
S
R
Site 6
S111
N
S
F
G
T
I
V
S
R
E
A
K
L
Q
F
Site 7
Y120
E
A
K
L
Q
F
A
Y
L
D
N
F
K
T
R
Site 8
T126
A
Y
L
D
N
F
K
T
R
T
R
S
T
V
S
Site 9
S130
N
F
K
T
R
T
R
S
T
V
S
V
R
R
G
Site 10
T131
F
K
T
R
T
R
S
T
V
S
V
R
R
G
Q
Site 11
S133
T
R
T
R
S
T
V
S
V
R
R
G
Q
G
M
Site 12
S150
L
C
G
P
P
P
H
S
G
E
L
S
Y
A
W
Site 13
S154
P
P
H
S
G
E
L
S
Y
A
W
I
F
N
E
Site 14
Y155
P
H
S
G
E
L
S
Y
A
W
I
F
N
E
Y
Site 15
Y162
Y
A
W
I
F
N
E
Y
P
S
Y
Q
D
N
R
Site 16
Y165
I
F
N
E
Y
P
S
Y
Q
D
N
R
R
F
V
Site 17
S173
Q
D
N
R
R
F
V
S
Q
E
T
G
N
L
Y
Site 18
T176
R
R
F
V
S
Q
E
T
G
N
L
Y
I
A
K
Site 19
Y180
S
Q
E
T
G
N
L
Y
I
A
K
V
E
K
S
Site 20
Y192
E
K
S
D
V
G
N
Y
T
C
V
V
T
N
T
Site 21
T193
K
S
D
V
G
N
Y
T
C
V
V
T
N
T
V
Site 22
T210
H
K
V
L
G
P
P
T
P
L
I
L
R
N
D
Site 23
Y223
N
D
G
V
M
G
E
Y
E
P
K
I
E
V
Q
Site 24
T237
Q
F
P
E
T
V
P
T
A
K
G
A
T
V
K
Site 25
S276
R
K
A
R
R
H
K
S
N
G
I
L
E
I
P
Site 26
Y293
Q
Q
E
D
A
G
L
Y
E
C
V
A
E
N
S
Site 27
Y313
A
R
G
Q
L
T
F
Y
A
Q
P
N
W
I
Q
Site 28
Y347
N
G
R
P
K
P
T
Y
K
W
L
K
N
G
E
Site 29
T358
K
N
G
E
P
L
L
T
R
D
R
I
Q
I
E
Site 30
S434
I
E
C
K
P
K
A
S
P
K
P
V
Y
T
W
Site 31
Y439
K
A
S
P
K
P
V
Y
T
W
K
K
G
R
D
Site 32
T455
L
K
E
N
E
R
I
T
I
S
E
D
G
N
L
Site 33
S457
E
N
E
R
I
T
I
S
E
D
G
N
L
R
I
Site 34
T468
N
L
R
I
I
N
V
T
K
S
D
A
G
S
Y
Site 35
S470
R
I
I
N
V
T
K
S
D
A
G
S
Y
T
C
Site 36
S474
V
T
K
S
D
A
G
S
Y
T
C
I
A
T
N
Site 37
T476
K
S
D
A
G
S
Y
T
C
I
A
T
N
H
F
Site 38
S487
T
N
H
F
G
T
A
S
S
T
G
N
L
V
V
Site 39
T498
N
L
V
V
K
D
P
T
R
V
M
V
P
P
S
Site 40
S557
E
R
V
G
G
Q
D
S
A
G
D
L
M
I
R
Site 41
Y574
Q
L
K
H
A
G
K
Y
V
C
M
V
Q
T
S
Site 42
T611
T
I
D
E
I
T
D
T
T
A
Q
L
S
W
R
Site 43
T612
I
D
E
I
T
D
T
T
A
Q
L
S
W
R
P
Site 44
S616
T
D
T
T
A
Q
L
S
W
R
P
G
P
D
N
Site 45
S625
R
P
G
P
D
N
H
S
P
I
T
M
Y
V
I
Site 46
T628
P
D
N
H
S
P
I
T
M
Y
V
I
Q
A
R
Site 47
Y630
N
H
S
P
I
T
M
Y
V
I
Q
A
R
T
P
Site 48
T660
D
G
K
T
F
T
A
T
V
V
G
L
N
P
W
Site 49
S686
V
I
G
I
G
E
P
S
R
P
S
E
K
R
R
Site 50
S689
I
G
E
P
S
R
P
S
E
K
R
R
T
E
E
Site 51
T694
R
P
S
E
K
R
R
T
E
E
A
L
P
E
V
Site 52
T702
E
E
A
L
P
E
V
T
P
A
N
V
S
G
G
Site 53
S707
E
V
T
P
A
N
V
S
G
G
G
G
S
K
S
Site 54
S714
S
G
G
G
G
S
K
S
E
L
V
I
T
W
E
Site 55
T719
S
K
S
E
L
V
I
T
W
E
T
V
P
E
E
Site 56
T722
E
L
V
I
T
W
E
T
V
P
E
E
L
Q
N
Site 57
Y735
Q
N
G
R
G
F
G
Y
V
V
A
F
R
P
Y
Site 58
S758
V
L
A
S
A
D
A
S
R
Y
V
F
R
N
E
Site 59
Y760
A
S
A
D
A
S
R
Y
V
F
R
N
E
S
V
Site 60
S766
R
Y
V
F
R
N
E
S
V
H
P
F
S
P
F
Site 61
S771
N
E
S
V
H
P
F
S
P
F
E
V
K
V
G
Site 62
S789
N
K
G
E
G
P
F
S
P
T
T
V
V
Y
S
Site 63
T792
E
G
P
F
S
P
T
T
V
V
Y
S
A
E
E
Site 64
S796
S
P
T
T
V
V
Y
S
A
E
E
E
P
T
K
Site 65
T802
Y
S
A
E
E
E
P
T
K
P
P
A
S
I
F
Site 66
S807
E
P
T
K
P
P
A
S
I
F
A
R
S
L
S
Site 67
S824
D
I
E
V
F
W
A
S
P
L
E
K
N
R
G
Site 68
Y836
N
R
G
R
I
Q
G
Y
E
V
K
Y
W
R
H
Site 69
Y840
I
Q
G
Y
E
V
K
Y
W
R
H
E
D
K
E
Site 70
T855
E
N
A
R
K
I
R
T
V
G
N
Q
T
S
T
Site 71
S861
R
T
V
G
N
Q
T
S
T
K
I
T
N
L
K
Site 72
T865
N
Q
T
S
T
K
I
T
N
L
K
G
S
V
L
Site 73
Y880
Y
H
L
A
V
K
A
Y
N
S
A
G
T
G
P
Site 74
S882
L
A
V
K
A
Y
N
S
A
G
T
G
P
S
S
Site 75
S889
S
A
G
T
G
P
S
S
A
T
V
N
V
T
T
Site 76
T891
G
T
G
P
S
S
A
T
V
N
V
T
T
R
K
Site 77
T895
S
S
A
T
V
N
V
T
T
R
K
P
P
P
S
Site 78
T896
S
A
T
V
N
V
T
T
R
K
P
P
P
S
Q
Site 79
S902
T
T
R
K
P
P
P
S
Q
P
P
G
N
I
I
Site 80
S912
P
G
N
I
I
W
N
S
S
D
S
K
I
I
L
Site 81
S913
G
N
I
I
W
N
S
S
D
S
K
I
I
L
N
Site 82
S931
V
K
A
L
D
N
E
S
E
V
K
G
Y
K
V
Site 83
Y936
N
E
S
E
V
K
G
Y
K
V
L
Y
R
W
N
Site 84
Y940
V
K
G
Y
K
V
L
Y
R
W
N
R
Q
S
S
Site 85
S946
L
Y
R
W
N
R
Q
S
S
T
S
V
I
E
T
Site 86
S947
Y
R
W
N
R
Q
S
S
T
S
V
I
E
T
N
Site 87
S949
W
N
R
Q
S
S
T
S
V
I
E
T
N
K
T
Site 88
T953
S
S
T
S
V
I
E
T
N
K
T
S
V
E
L
Site 89
T956
S
V
I
E
T
N
K
T
S
V
E
L
S
L
P
Site 90
S961
N
K
T
S
V
E
L
S
L
P
F
D
E
D
Y
Site 91
Y968
S
L
P
F
D
E
D
Y
I
I
E
I
K
P
F
Site 92
S976
I
I
E
I
K
P
F
S
D
G
G
D
G
S
S
Site 93
S982
F
S
D
G
G
D
G
S
S
S
E
Q
I
R
I
Site 94
S983
S
D
G
G
D
G
S
S
S
E
Q
I
R
I
P
Site 95
S984
D
G
G
D
G
S
S
S
E
Q
I
R
I
P
K
Site 96
S993
Q
I
R
I
P
K
I
S
N
A
Y
A
R
G
S
Site 97
Y996
I
P
K
I
S
N
A
Y
A
R
G
S
G
A
S
Site 98
S1000
S
N
A
Y
A
R
G
S
G
A
S
T
S
N
A
Site 99
S1003
Y
A
R
G
S
G
A
S
T
S
N
A
C
T
L
Site 100
T1004
A
R
G
S
G
A
S
T
S
N
A
C
T
L
S
Site 101
S1005
R
G
S
G
A
S
T
S
N
A
C
T
L
S
A
Site 102
T1021
S
T
I
M
I
S
L
T
A
R
S
S
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation