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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHERP
Full Name:
Calcium homeostasis endoplasmic reticulum protein
Alias:
DAN16; ERPROT213-21; Protein with polyglutamine repeat; SCAF6; SR-related CTD associated factor 6
Type:
Endoplasmic reticulum
Mass (Da):
103573
Number AA:
916
UniProt ID:
Q8IWX8
International Prot ID:
IPI00333010
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005737
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003723
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006396
GO:0006873
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S45
Q
K
D
N
P
K
F
S
F
L
F
G
G
E
F
Site 2
Y55
F
G
G
E
F
Y
S
Y
Y
K
C
K
L
A
L
Site 3
Y56
G
G
E
F
Y
S
Y
Y
K
C
K
L
A
L
E
Site 4
T73
Q
L
I
C
K
Q
Q
T
P
E
L
E
P
A
A
Site 5
T81
P
E
L
E
P
A
A
T
M
P
P
L
P
Q
P
Site 6
S104
P
P
A
Q
G
A
P
S
M
D
E
L
I
Q
Q
Site 7
T169
Q
P
I
I
D
T
C
T
K
D
A
I
S
A
G
Site 8
S186
W
M
F
S
N
A
K
S
P
P
H
C
E
L
M
Site 9
T202
G
H
L
R
N
R
I
T
A
D
G
A
H
F
E
Site 10
Y272
Q
L
W
E
K
N
G
Y
F
D
D
S
I
I
Q
Site 11
S276
K
N
G
Y
F
D
D
S
I
I
Q
Q
L
Q
S
Site 12
T294
G
L
G
Q
Y
Q
A
T
L
I
N
E
Y
S
S
Site 13
S327
Q
H
E
E
F
V
T
S
L
A
Q
Q
Q
Q
Q
Site 14
T354
M
E
A
E
V
K
A
T
P
P
P
P
A
P
P
Site 15
T373
P
A
P
A
I
P
P
T
T
Q
P
D
D
S
K
Site 16
T374
A
P
A
I
P
P
T
T
Q
P
D
D
S
K
P
Site 17
S379
P
T
T
Q
P
D
D
S
K
P
P
I
Q
M
P
Site 18
S388
P
P
I
Q
M
P
G
S
S
E
Y
E
A
P
G
Site 19
S389
P
I
Q
M
P
G
S
S
E
Y
E
A
P
G
G
Site 20
Y391
Q
M
P
G
S
S
E
Y
E
A
P
G
G
V
Q
Site 21
Y442
Q
P
P
E
Q
P
P
Y
P
H
H
Q
G
G
P
Site 22
Y567
H
P
F
E
R
P
P
Y
P
H
R
F
D
Y
P
Site 23
Y573
P
Y
P
H
R
F
D
Y
P
Q
G
D
F
P
A
Site 24
S640
H
I
N
H
D
D
P
S
L
V
P
N
V
P
Y
Site 25
Y666
V
K
L
E
D
H
E
Y
K
P
L
D
P
K
D
Site 26
S683
L
P
P
P
M
P
P
S
E
R
L
L
A
A
V
Site 27
Y694
L
A
A
V
E
A
F
Y
S
P
P
S
H
D
R
Site 28
S695
A
A
V
E
A
F
Y
S
P
P
S
H
D
R
P
Site 29
S698
E
A
F
Y
S
P
P
S
H
D
R
P
R
N
S
Site 30
S705
S
H
D
R
P
R
N
S
E
G
W
E
Q
N
G
Site 31
Y714
G
W
E
Q
N
G
L
Y
E
F
F
R
A
K
M
Site 32
S734
K
G
Q
E
K
R
N
S
G
P
S
R
S
R
S
Site 33
S737
E
K
R
N
S
G
P
S
R
S
R
S
R
S
K
Site 34
S739
R
N
S
G
P
S
R
S
R
S
R
S
K
S
R
Site 35
S741
S
G
P
S
R
S
R
S
R
S
K
S
R
G
R
Site 36
S743
P
S
R
S
R
S
R
S
K
S
R
G
R
S
S
Site 37
S745
R
S
R
S
R
S
K
S
R
G
R
S
S
S
R
Site 38
S749
R
S
K
S
R
G
R
S
S
S
R
S
N
S
R
Site 39
S750
S
K
S
R
G
R
S
S
S
R
S
N
S
R
S
Site 40
S751
K
S
R
G
R
S
S
S
R
S
N
S
R
S
S
Site 41
S753
R
G
R
S
S
S
R
S
N
S
R
S
S
K
S
Site 42
S755
R
S
S
S
R
S
N
S
R
S
S
K
S
S
G
Site 43
S757
S
S
R
S
N
S
R
S
S
K
S
S
G
S
Y
Site 44
S758
S
R
S
N
S
R
S
S
K
S
S
G
S
Y
S
Site 45
S760
S
N
S
R
S
S
K
S
S
G
S
Y
S
R
S
Site 46
S761
N
S
R
S
S
K
S
S
G
S
Y
S
R
S
R
Site 47
S763
R
S
S
K
S
S
G
S
Y
S
R
S
R
S
R
Site 48
Y764
S
S
K
S
S
G
S
Y
S
R
S
R
S
R
S
Site 49
S765
S
K
S
S
G
S
Y
S
R
S
R
S
R
S
C
Site 50
S767
S
S
G
S
Y
S
R
S
R
S
R
S
C
S
R
Site 51
S769
G
S
Y
S
R
S
R
S
R
S
C
S
R
S
S
Site 52
S771
Y
S
R
S
R
S
R
S
C
S
R
S
S
S
C
Site 53
S773
R
S
R
S
R
S
C
S
R
S
S
S
C
S
R
Site 54
S775
R
S
R
S
C
S
R
S
S
S
C
S
R
S
R
Site 55
S776
S
R
S
C
S
R
S
S
S
C
S
R
S
R
S
Site 56
S777
R
S
C
S
R
S
S
S
C
S
R
S
R
S
R
Site 57
S779
C
S
R
S
S
S
C
S
R
S
R
S
R
S
R
Site 58
S781
R
S
S
S
C
S
R
S
R
S
R
S
R
S
R
Site 59
S783
S
S
C
S
R
S
R
S
R
S
R
S
R
S
S
Site 60
S785
C
S
R
S
R
S
R
S
R
S
R
S
S
R
S
Site 61
S787
R
S
R
S
R
S
R
S
R
S
S
R
S
R
S
Site 62
S789
R
S
R
S
R
S
R
S
S
R
S
R
S
R
S
Site 63
S790
S
R
S
R
S
R
S
S
R
S
R
S
R
S
Q
Site 64
S792
S
R
S
R
S
S
R
S
R
S
R
S
Q
S
R
Site 65
S794
S
R
S
S
R
S
R
S
R
S
Q
S
R
S
R
Site 66
S796
S
S
R
S
R
S
R
S
Q
S
R
S
R
S
K
Site 67
S798
R
S
R
S
R
S
Q
S
R
S
R
S
K
S
Y
Site 68
S800
R
S
R
S
Q
S
R
S
R
S
K
S
Y
S
P
Site 69
S802
R
S
Q
S
R
S
R
S
K
S
Y
S
P
G
R
Site 70
S804
Q
S
R
S
R
S
K
S
Y
S
P
G
R
R
R
Site 71
Y805
S
R
S
R
S
K
S
Y
S
P
G
R
R
R
R
Site 72
S806
R
S
R
S
K
S
Y
S
P
G
R
R
R
R
S
Site 73
S813
S
P
G
R
R
R
R
S
R
S
R
S
P
T
P
Site 74
S815
G
R
R
R
R
S
R
S
R
S
P
T
P
P
S
Site 75
S817
R
R
R
S
R
S
R
S
P
T
P
P
S
S
A
Site 76
T819
R
S
R
S
R
S
P
T
P
P
S
S
A
G
L
Site 77
S822
S
R
S
P
T
P
P
S
S
A
G
L
G
S
N
Site 78
S823
R
S
P
T
P
P
S
S
A
G
L
G
S
N
S
Site 79
S828
P
S
S
A
G
L
G
S
N
S
A
P
P
I
P
Site 80
S830
S
A
G
L
G
S
N
S
A
P
P
I
P
D
S
Site 81
S837
S
A
P
P
I
P
D
S
R
L
G
E
E
N
K
Site 82
S857
V
K
M
G
W
S
G
S
G
G
L
G
A
K
E
Site 83
Y883
V
R
D
K
W
D
Q
Y
K
G
V
G
V
A
L
Site 84
Y894
G
V
A
L
D
D
P
Y
E
N
Y
R
R
N
K
Site 85
Y897
L
D
D
P
Y
E
N
Y
R
R
N
K
S
Y
S
Site 86
S902
E
N
Y
R
R
N
K
S
Y
S
F
I
A
R
M
Site 87
Y903
N
Y
R
R
N
K
S
Y
S
F
I
A
R
M
K
Site 88
S904
Y
R
R
N
K
S
Y
S
F
I
A
R
M
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation