KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TRIM42
Full Name:
Tripartite motif-containing protein 42
Alias:
FLJ40097; TRI42; tripartite motif 42; tripartite motif-containing 42
Type:
Unknown function
Mass (Da):
82773
Number AA:
723
UniProt ID:
Q8IWZ5
International Prot ID:
IPI00217444
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y89
A
S
S
N
L
N
C
Y
Y
Y
E
S
R
C
C
Site 2
Y90
S
S
N
L
N
C
Y
Y
Y
E
S
R
C
C
R
Site 3
Y91
S
N
L
N
C
Y
Y
Y
E
S
R
C
C
R
N
Site 4
S110
F
H
K
G
R
L
R
S
I
H
T
S
S
K
T
Site 5
S114
R
L
R
S
I
H
T
S
S
K
T
A
L
R
T
Site 6
S115
L
R
S
I
H
T
S
S
K
T
A
L
R
T
G
Site 7
T117
S
I
H
T
S
S
K
T
A
L
R
T
G
S
S
Site 8
S123
K
T
A
L
R
T
G
S
S
D
T
Q
V
D
E
Site 9
S124
T
A
L
R
T
G
S
S
D
T
Q
V
D
E
V
Site 10
S133
T
Q
V
D
E
V
K
S
I
P
A
N
S
H
L
Site 11
Y209
K
M
Q
L
P
E
N
Y
L
H
G
R
L
T
K
Site 12
Y218
H
G
R
L
T
K
R
Y
M
Q
E
H
G
Y
L
Site 13
Y224
R
Y
M
Q
E
H
G
Y
L
K
W
R
F
D
R
Site 14
S232
L
K
W
R
F
D
R
S
S
G
P
I
L
C
Q
Site 15
S233
K
W
R
F
D
R
S
S
G
P
I
L
C
Q
V
Site 16
S281
D
H
V
F
V
D
T
S
A
E
E
Q
D
E
K
Site 17
Y301
P
S
S
R
I
I
E
Y
C
R
N
D
N
K
L
Site 18
T323
S
F
H
N
G
H
D
T
I
S
L
I
D
A
C
Site 19
S325
H
N
G
H
D
T
I
S
L
I
D
A
C
S
E
Site 20
Y349
A
K
F
K
A
V
R
Y
E
I
D
N
D
L
M
Site 21
S364
E
F
N
I
L
K
N
S
F
K
A
D
K
E
A
Site 22
Y412
R
Q
K
E
I
E
K
Y
V
Y
V
T
T
M
K
Site 23
Y414
K
E
I
E
K
Y
V
Y
V
T
T
M
K
V
N
Site 24
T416
I
E
K
Y
V
Y
V
T
T
M
K
V
N
E
M
Site 25
T417
E
K
Y
V
Y
V
T
T
M
K
V
N
E
M
D
Site 26
T460
I
E
D
G
I
Q
T
T
Y
R
P
D
P
Q
L
Site 27
S471
D
P
Q
L
R
L
H
S
I
N
Y
V
P
L
D
Site 28
T492
A
I
H
E
L
F
P
T
G
P
K
K
V
R
S
Site 29
S499
T
G
P
K
K
V
R
S
S
G
D
S
L
P
S
Site 30
S500
G
P
K
K
V
R
S
S
G
D
S
L
P
S
P
Site 31
S503
K
V
R
S
S
G
D
S
L
P
S
P
Y
P
V
Site 32
S506
S
S
G
D
S
L
P
S
P
Y
P
V
H
S
E
Site 33
Y508
G
D
S
L
P
S
P
Y
P
V
H
S
E
T
M
Site 34
S512
P
S
P
Y
P
V
H
S
E
T
M
I
A
R
K
Site 35
S523
I
A
R
K
V
T
F
S
T
H
S
L
G
N
Q
Site 36
S526
K
V
T
F
S
T
H
S
L
G
N
Q
H
I
Y
Site 37
Y533
S
L
G
N
Q
H
I
Y
Q
R
S
S
S
M
L
Site 38
S536
N
Q
H
I
Y
Q
R
S
S
S
M
L
S
F
S
Site 39
S537
Q
H
I
Y
Q
R
S
S
S
M
L
S
F
S
N
Site 40
S538
H
I
Y
Q
R
S
S
S
M
L
S
F
S
N
T
Site 41
S541
Q
R
S
S
S
M
L
S
F
S
N
T
D
K
K
Site 42
S543
S
S
S
M
L
S
F
S
N
T
D
K
K
A
K
Site 43
T545
S
M
L
S
F
S
N
T
D
K
K
A
K
V
G
Site 44
S561
E
A
C
G
R
A
Q
S
A
T
P
A
K
P
T
Site 45
T563
C
G
R
A
Q
S
A
T
P
A
K
P
T
D
G
Site 46
Y572
A
K
P
T
D
G
L
Y
T
Y
W
S
A
G
A
Site 47
Y574
P
T
D
G
L
Y
T
Y
W
S
A
G
A
D
S
Site 48
S576
D
G
L
Y
T
Y
W
S
A
G
A
D
S
Q
S
Site 49
S581
Y
W
S
A
G
A
D
S
Q
S
V
Q
N
S
S
Site 50
S583
S
A
G
A
D
S
Q
S
V
Q
N
S
S
S
F
Site 51
S587
D
S
Q
S
V
Q
N
S
S
S
F
H
N
W
Y
Site 52
Y594
S
S
S
F
H
N
W
Y
S
F
N
D
G
S
V
Site 53
S600
W
Y
S
F
N
D
G
S
V
K
T
P
G
P
I
Site 54
Y622
Y
P
R
A
A
K
V
Y
W
T
C
P
A
E
D
Site 55
S632
C
P
A
E
D
V
D
S
F
E
M
E
F
Y
E
Site 56
Y638
D
S
F
E
M
E
F
Y
E
V
I
T
S
P
P
Site 57
S643
E
F
Y
E
V
I
T
S
P
P
N
N
V
Q
M
Site 58
T670
N
L
E
L
H
N
L
T
P
N
T
E
Y
V
F
Site 59
T673
L
H
N
L
T
P
N
T
E
Y
V
F
K
V
R
Site 60
Y675
N
L
T
P
N
T
E
Y
V
F
K
V
R
A
I
Site 61
T698
S
D
I
C
K
V
V
T
P
D
G
H
G
K
N
Site 62
S717
G
L
L
K
N
I
Q
S
A
L
Q
K
H
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation