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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UEVLD
Full Name:
Ubiquitin-conjugating enzyme E2 variant 3
Alias:
ATTP; EV and lactate/malate dehydrogenase domain-containing; UEV3
Type:
Mass (Da):
52264
Number AA:
471
UniProt ID:
Q8IX04
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0016616
GO:0019787
PhosphoSite+
KinaseNET
Biological Process:
GO:0006096
GO:0019941
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y15
L
R
R
L
L
G
K
Y
K
F
R
D
L
T
V
Site 2
T21
K
Y
K
F
R
D
L
T
V
E
E
L
R
N
V
Site 3
Y42
F
K
Y
S
M
D
T
Y
V
F
K
D
S
S
Q
Site 4
S48
T
Y
V
F
K
D
S
S
Q
K
D
L
L
N
F
Site 5
Y63
T
G
T
I
P
V
M
Y
Q
G
N
T
Y
N
I
Site 6
Y110
V
D
A
Q
G
R
I
Y
L
P
Y
L
Q
N
W
Site 7
Y113
Q
G
R
I
Y
L
P
Y
L
Q
N
W
S
H
P
Site 8
S122
Q
N
W
S
H
P
K
S
V
I
V
G
L
I
K
Site 9
Y142
F
Q
E
E
L
P
M
Y
S
L
S
S
S
D
E
Site 10
S143
Q
E
E
L
P
M
Y
S
L
S
S
S
D
E
A
Site 11
S145
E
L
P
M
Y
S
L
S
S
S
D
E
A
R
Q
Site 12
S147
P
M
Y
S
L
S
S
S
D
E
A
R
Q
V
D
Site 13
S167
A
K
I
T
E
G
V
S
D
T
N
S
K
S
W
Site 14
T169
I
T
E
G
V
S
D
T
N
S
K
S
W
A
N
Site 15
S171
E
G
V
S
D
T
N
S
K
S
W
A
N
H
E
Site 16
S173
V
S
D
T
N
S
K
S
W
A
N
H
E
N
K
Site 17
T181
W
A
N
H
E
N
K
T
V
N
K
I
T
V
V
Site 18
T186
N
K
T
V
N
K
I
T
V
V
G
G
G
E
L
Site 19
S237
N
L
P
N
V
E
I
S
K
D
L
S
A
S
A
Site 20
S241
V
E
I
S
K
D
L
S
A
S
A
H
S
K
V
Site 21
S261
N
S
L
G
S
S
Q
S
Y
L
D
V
V
Q
S
Site 22
Y262
S
L
G
S
S
Q
S
Y
L
D
V
V
Q
S
N
Site 23
S268
S
Y
L
D
V
V
Q
S
N
V
D
M
F
R
A
Site 24
Y301
Q
P
V
E
I
M
T
Y
V
T
W
K
L
S
T
Site 25
S323
G
I
G
C
N
L
D
S
Q
R
L
Q
Y
I
I
Site 26
Y328
L
D
S
Q
R
L
Q
Y
I
I
T
N
V
L
K
Site 27
T356
Q
G
E
D
K
V
L
T
W
S
G
Q
E
E
V
Site 28
S358
E
D
K
V
L
T
W
S
G
Q
E
E
V
V
S
Site 29
S365
S
G
Q
E
E
V
V
S
H
T
S
Q
V
Q
L
Site 30
T367
Q
E
E
V
V
S
H
T
S
Q
V
Q
L
S
N
Site 31
S368
E
E
V
V
S
H
T
S
Q
V
Q
L
S
N
R
Site 32
S373
H
T
S
Q
V
Q
L
S
N
R
A
M
E
L
L
Site 33
S387
L
R
V
K
G
Q
R
S
W
S
V
G
L
S
V
Site 34
S389
V
K
G
Q
R
S
W
S
V
G
L
S
V
A
D
Site 35
S412
K
K
K
V
H
S
V
S
A
L
A
K
G
Y
Y
Site 36
Y419
S
A
L
A
K
G
Y
Y
D
I
N
S
E
V
F
Site 37
S423
K
G
Y
Y
D
I
N
S
E
V
F
L
S
L
P
Site 38
T444
G
V
S
E
V
I
K
T
T
L
K
E
D
T
V
Site 39
T450
K
T
T
L
K
E
D
T
V
T
E
K
L
Q
S
Site 40
T452
T
L
K
E
D
T
V
T
E
K
L
Q
S
S
A
Site 41
S457
T
V
T
E
K
L
Q
S
S
A
S
S
I
H
S
Site 42
S458
V
T
E
K
L
Q
S
S
A
S
S
I
H
S
L
Site 43
S460
E
K
L
Q
S
S
A
S
S
I
H
S
L
Q
Q
Site 44
S461
K
L
Q
S
S
A
S
S
I
H
S
L
Q
Q
Q
Site 45
S464
S
S
A
S
S
I
H
S
L
Q
Q
Q
L
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation