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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
REXO1L1
Full Name:
Exonuclease GOR
Alias:
Antigen GOR homolog;RNA exonuclease 1 homolog-like 1
Type:
Mass (Da):
73855
Number AA:
675
UniProt ID:
Q8IX06
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
P
C
W
F
P
P
G
Y
P
E
A
K
K
V
A
Site 2
S37
R
H
L
G
G
E
Q
S
Q
A
G
A
P
E
G
Site 3
T51
G
S
K
M
L
R
A
T
A
P
C
W
F
R
P
Site 4
Y60
P
C
W
F
R
P
G
Y
P
E
A
K
K
V
A
Site 5
S83
R
H
L
G
A
E
Q
S
P
A
G
A
P
E
G
Site 6
T97
G
S
K
M
L
R
A
T
A
P
C
W
F
P
P
Site 7
S127
A
P
E
F
P
L
P
S
H
Q
P
A
Q
S
F
Site 8
S133
P
S
H
Q
P
A
Q
S
F
G
L
W
V
P
Q
Site 9
Y175
K
M
V
T
E
S
C
Y
F
P
A
Q
R
G
S
Site 10
S182
Y
F
P
A
Q
R
G
S
A
C
R
L
P
A
A
Site 11
T193
L
P
A
A
P
R
L
T
E
R
P
S
G
V
R
Site 12
S197
P
R
L
T
E
R
P
S
G
V
R
I
S
A
P
Site 13
S202
R
P
S
G
V
R
I
S
A
P
R
K
R
K
T
Site 14
T209
S
A
P
R
K
R
K
T
I
A
H
S
S
S
P
Site 15
S213
K
R
K
T
I
A
H
S
S
S
P
C
L
V
T
Site 16
S214
R
K
T
I
A
H
S
S
S
P
C
L
V
T
G
Site 17
S215
K
T
I
A
H
S
S
S
P
C
L
V
T
G
Y
Site 18
T223
P
C
L
V
T
G
Y
T
D
A
K
R
T
R
V
Site 19
T228
G
Y
T
D
A
K
R
T
R
V
A
S
S
S
Q
Site 20
S232
A
K
R
T
R
V
A
S
S
S
Q
R
S
R
G
Site 21
S233
K
R
T
R
V
A
S
S
S
Q
R
S
R
G
S
Site 22
S234
R
T
R
V
A
S
S
S
Q
R
S
R
G
S
K
Site 23
S237
V
A
S
S
S
Q
R
S
R
G
S
K
V
G
R
Site 24
S240
S
S
Q
R
S
R
G
S
K
V
G
R
Q
P
G
Site 25
T249
V
G
R
Q
P
G
K
T
R
N
R
S
G
M
A
Site 26
S253
P
G
K
T
R
N
R
S
G
M
A
C
K
T
T
Site 27
T259
R
S
G
M
A
C
K
T
T
A
T
T
S
S
K
Site 28
T260
S
G
M
A
C
K
T
T
A
T
T
S
S
K
R
Site 29
T262
M
A
C
K
T
T
A
T
T
S
S
K
R
I
V
Site 30
S264
C
K
T
T
A
T
T
S
S
K
R
I
V
R
R
Site 31
S265
K
T
T
A
T
T
S
S
K
R
I
V
R
R
A
Site 32
S273
K
R
I
V
R
R
A
S
L
P
S
L
S
L
K
Site 33
S276
V
R
R
A
S
L
P
S
L
S
L
K
K
P
I
Site 34
S287
K
K
P
I
I
L
R
S
S
G
C
Q
V
P
T
Site 35
T294
S
S
G
C
Q
V
P
T
V
L
R
R
G
Y
L
Site 36
Y300
P
T
V
L
R
R
G
Y
L
Q
L
F
T
E
E
Site 37
S314
E
C
L
K
F
C
A
S
K
Q
E
A
E
E
K
Site 38
Y330
L
N
E
E
K
V
A
Y
D
C
S
P
N
K
N
Site 39
S333
E
K
V
A
Y
D
C
S
P
N
K
N
R
Y
L
Site 40
Y339
C
S
P
N
K
N
R
Y
L
N
V
V
L
N
T
Site 41
T354
L
K
R
L
K
G
L
T
P
S
S
M
P
G
L
Site 42
S356
R
L
K
G
L
T
P
S
S
M
P
G
L
S
R
Site 43
S357
L
K
G
L
T
P
S
S
M
P
G
L
S
R
A
Site 44
S362
P
S
S
M
P
G
L
S
R
A
A
L
Y
S
R
Site 45
Y367
G
L
S
R
A
A
L
Y
S
R
L
Q
E
F
L
Site 46
S368
L
S
R
A
A
L
Y
S
R
L
Q
E
F
L
L
Site 47
T376
R
L
Q
E
F
L
L
T
Q
D
Q
L
K
E
N
Site 48
Y385
D
Q
L
K
E
N
G
Y
P
F
P
H
P
E
R
Site 49
T400
P
G
G
A
V
L
F
T
G
Q
G
K
G
P
G
Site 50
S409
Q
G
K
G
P
G
D
S
S
C
R
V
C
C
R
Site 51
T419
R
V
C
C
R
C
G
T
E
Y
L
V
S
S
S
Site 52
Y421
C
C
R
C
G
T
E
Y
L
V
S
S
S
G
R
Site 53
S424
C
G
T
E
Y
L
V
S
S
S
G
R
C
V
R
Site 54
S426
T
E
Y
L
V
S
S
S
G
R
C
V
R
D
Q
Site 55
Y437
V
R
D
Q
L
C
Y
Y
H
W
G
R
V
R
S
Site 56
S444
Y
H
W
G
R
V
R
S
S
Q
V
A
G
G
R
Site 57
S445
H
W
G
R
V
R
S
S
Q
V
A
G
G
R
V
Site 58
T456
G
G
R
V
S
Q
Y
T
C
C
A
A
A
P
G
Site 59
S481
V
R
D
G
R
K
E
S
L
D
G
F
V
E
T
Site 60
T488
S
L
D
G
F
V
E
T
F
K
K
E
L
S
R
Site 61
S494
E
T
F
K
K
E
L
S
R
D
A
Y
P
G
I
Site 62
Y498
K
E
L
S
R
D
A
Y
P
G
I
Y
A
L
D
Site 63
Y531
D
A
D
M
R
V
V
Y
D
T
F
V
K
P
D
Site 64
T533
D
M
R
V
V
Y
D
T
F
V
K
P
D
N
E
Site 65
Y544
P
D
N
E
I
V
D
Y
N
T
R
F
S
G
V
Site 66
S549
V
D
Y
N
T
R
F
S
G
V
T
E
A
D
V
Site 67
Y614
P
H
Y
L
G
F
P
Y
K
R
S
L
R
N
L
Site 68
S617
L
G
F
P
Y
K
R
S
L
R
N
L
A
A
D
Site 69
S633
L
A
Q
I
I
Q
D
S
Q
D
G
H
N
S
S
Site 70
S639
D
S
Q
D
G
H
N
S
S
E
D
A
S
A
C
Site 71
S640
S
Q
D
G
H
N
S
S
E
D
A
S
A
C
L
Site 72
S644
H
N
S
S
E
D
A
S
A
C
L
Q
L
V
M
Site 73
S666
Q
I
Q
P
R
H
R
S
A
S
P
A
A
L
A
Site 74
S668
Q
P
R
H
R
S
A
S
P
A
A
L
A
C
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation