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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HOMEZ
Full Name:
Homeobox and leucine zipper protein Homez
Alias:
Homeodomain leucine zipper-containing factor
Type:
Transcription protein
Mass (Da):
58575
Number AA:
525
UniProt ID:
Q8IX15
International Prot ID:
IPI00477303
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
P
P
N
K
E
A
S
G
L
S
S
S
P
A
Site 2
S11
N
K
E
A
S
G
L
S
S
S
P
A
G
L
I
Site 3
S38
W
T
Q
A
A
Q
T
S
E
L
D
S
N
E
H
Site 4
S42
A
Q
T
S
E
L
D
S
N
E
H
L
L
K
T
Site 5
T49
S
N
E
H
L
L
K
T
F
S
Y
F
P
Y
P
Site 6
S51
E
H
L
L
K
T
F
S
Y
F
P
Y
P
S
L
Site 7
Y55
K
T
F
S
Y
F
P
Y
P
S
L
A
D
I
A
Site 8
S89
Q
R
L
R
C
G
I
S
W
S
S
E
E
I
E
Site 9
S91
L
R
C
G
I
S
W
S
S
E
E
I
E
E
T
Site 10
S92
R
C
G
I
S
W
S
S
E
E
I
E
E
T
R
Site 11
T98
S
S
E
E
I
E
E
T
R
A
R
V
V
Y
R
Site 12
Y104
E
T
R
A
R
V
V
Y
R
R
D
Q
L
H
F
Site 13
S113
R
D
Q
L
H
F
K
S
L
L
S
F
T
H
H
Site 14
S116
L
H
F
K
S
L
L
S
F
T
H
H
A
G
R
Site 15
T147
G
I
G
I
G
P
P
T
L
S
K
P
T
Q
T
Site 16
S149
G
I
G
P
P
T
L
S
K
P
T
Q
T
K
G
Site 17
S165
K
V
E
P
E
E
P
S
Q
M
P
P
L
P
Q
Site 18
S173
Q
M
P
P
L
P
Q
S
H
Q
K
L
K
E
S
Site 19
S180
S
H
Q
K
L
K
E
S
L
M
T
P
G
S
G
Site 20
T183
K
L
K
E
S
L
M
T
P
G
S
G
A
F
P
Site 21
S186
E
S
L
M
T
P
G
S
G
A
F
P
Y
Q
S
Site 22
Y191
P
G
S
G
A
F
P
Y
Q
S
D
F
W
Q
H
Site 23
S201
D
F
W
Q
H
L
Q
S
S
G
L
S
K
E
Q
Site 24
S205
H
L
Q
S
S
G
L
S
K
E
Q
A
G
R
G
Site 25
S216
A
G
R
G
P
N
Q
S
H
G
I
G
T
A
S
Site 26
S223
S
H
G
I
G
T
A
S
W
N
H
S
T
T
V
Site 27
S227
G
T
A
S
W
N
H
S
T
T
V
P
Q
P
Q
Site 28
T228
T
A
S
W
N
H
S
T
T
V
P
Q
P
Q
A
Site 29
T229
A
S
W
N
H
S
T
T
V
P
Q
P
Q
A
R
Site 30
S253
A
S
S
C
K
E
E
S
A
S
S
V
T
P
S
Site 31
S255
S
C
K
E
E
S
A
S
S
V
T
P
S
S
S
Site 32
S256
C
K
E
E
S
A
S
S
V
T
P
S
S
S
S
Site 33
T258
E
E
S
A
S
S
V
T
P
S
S
S
S
T
S
Site 34
S260
S
A
S
S
V
T
P
S
S
S
S
T
S
S
S
Site 35
S261
A
S
S
V
T
P
S
S
S
S
T
S
S
S
F
Site 36
S262
S
S
V
T
P
S
S
S
S
T
S
S
S
F
Q
Site 37
S263
S
V
T
P
S
S
S
S
T
S
S
S
F
Q
V
Site 38
T264
V
T
P
S
S
S
S
T
S
S
S
F
Q
V
L
Site 39
S265
T
P
S
S
S
S
T
S
S
S
F
Q
V
L
A
Site 40
S266
P
S
S
S
S
T
S
S
S
F
Q
V
L
A
N
Site 41
S267
S
S
S
S
T
S
S
S
F
Q
V
L
A
N
G
Site 42
S291
P
L
G
C
V
P
Q
S
V
S
P
S
E
Q
A
Site 43
S293
G
C
V
P
Q
S
V
S
P
S
E
Q
A
L
P
Site 44
S295
V
P
Q
S
V
S
P
S
E
Q
A
L
P
P
H
Site 45
S315
P
Q
G
L
R
H
N
S
V
P
G
R
V
G
P
Site 46
T323
V
P
G
R
V
G
P
T
E
Y
L
S
P
D
M
Site 47
Y325
G
R
V
G
P
T
E
Y
L
S
P
D
M
Q
R
Site 48
S327
V
G
P
T
E
Y
L
S
P
D
M
Q
R
Q
R
Site 49
T336
D
M
Q
R
Q
R
K
T
K
R
K
T
K
E
Q
Site 50
T340
Q
R
K
T
K
R
K
T
K
E
Q
L
A
I
L
Site 51
Y362
Q
W
A
R
R
E
D
Y
Q
K
L
E
Q
I
T
Site 52
Y385
Q
W
F
G
D
T
R
Y
A
L
K
H
G
Q
L
Site 53
S405
N
A
V
P
G
A
P
S
F
Q
D
P
A
I
P
Site 54
T413
F
Q
D
P
A
I
P
T
P
P
P
S
T
R
S
Site 55
S417
A
I
P
T
P
P
P
S
T
R
S
L
N
E
R
Site 56
S420
T
P
P
P
S
T
R
S
L
N
E
R
A
E
T
Site 57
T427
S
L
N
E
R
A
E
T
P
P
L
P
I
P
P
Site 58
T455
A
H
Q
Q
L
R
E
T
D
I
P
Q
L
S
Q
Site 59
S461
E
T
D
I
P
Q
L
S
Q
A
S
R
L
S
T
Site 60
S467
L
S
Q
A
S
R
L
S
T
Q
Q
V
L
D
W
Site 61
T468
S
Q
A
S
R
L
S
T
Q
Q
V
L
D
W
F
Site 62
S477
Q
V
L
D
W
F
D
S
R
L
P
Q
P
A
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation