KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RHOT2
Full Name:
Mitochondrial Rho GTPase 2
Alias:
Ras homolog gene family member T2
Type:
Mass (Da):
68118
Number AA:
618
UniProt ID:
Q8IXI1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T41
P
P
R
A
E
E
I
T
I
P
A
D
V
T
P
Site 2
T47
I
T
I
P
A
D
V
T
P
E
K
V
P
T
H
Site 3
T53
V
T
P
E
K
V
P
T
H
I
V
D
Y
S
E
Site 4
Y58
V
P
T
H
I
V
D
Y
S
E
A
E
Q
T
D
Site 5
S59
P
T
H
I
V
D
Y
S
E
A
E
Q
T
D
E
Site 6
T64
D
Y
S
E
A
E
Q
T
D
E
E
L
R
E
E
Site 7
T95
A
T
I
E
K
I
R
T
K
W
I
P
L
V
N
Site 8
S120
I
I
L
V
G
N
K
S
D
L
R
S
G
S
S
Site 9
S124
G
N
K
S
D
L
R
S
G
S
S
M
E
A
V
Site 10
S126
K
S
D
L
R
S
G
S
S
M
E
A
V
L
P
Site 11
S127
S
D
L
R
S
G
S
S
M
E
A
V
L
P
I
Site 12
S156
A
K
N
L
R
N
I
S
E
L
F
Y
Y
A
Q
Site 13
Y160
R
N
I
S
E
L
F
Y
Y
A
Q
K
A
V
L
Site 14
Y174
L
H
P
T
A
P
L
Y
D
P
E
A
K
Q
L
Site 15
S196
L
T
R
I
F
R
L
S
D
Q
D
L
D
Q
A
Site 16
S205
Q
D
L
D
Q
A
L
S
D
E
E
L
N
A
F
Site 17
S215
E
L
N
A
F
Q
K
S
C
F
G
H
P
L
A
Site 18
T266
I
Q
R
G
R
H
E
T
T
W
T
I
L
R
R
Site 19
T269
G
R
H
E
T
T
W
T
I
L
R
R
F
G
Y
Site 20
Y276
T
I
L
R
R
F
G
Y
S
D
A
L
E
L
T
Site 21
T283
Y
S
D
A
L
E
L
T
A
D
Y
L
S
P
L
Site 22
Y306
T
E
L
N
H
L
G
Y
Q
F
V
Q
R
V
F
Site 23
S325
Q
D
R
D
G
A
L
S
P
V
E
L
Q
S
L
Site 24
T348
W
G
P
E
L
P
R
T
V
R
T
E
A
G
R
Site 25
Y385
G
H
L
G
Y
L
G
Y
P
T
L
C
E
Q
D
Site 26
T387
L
G
Y
L
G
Y
P
T
L
C
E
Q
D
Q
A
Site 27
T398
Q
D
Q
A
H
A
I
T
V
T
R
E
K
R
L
Site 28
T412
L
D
Q
E
K
G
Q
T
Q
R
S
V
L
L
C
Site 29
T446
R
G
L
G
H
Q
D
T
R
E
Q
P
P
G
Y
Site 30
Y453
T
R
E
Q
P
P
G
Y
A
I
D
T
V
Q
V
Site 31
T457
P
P
G
Y
A
I
D
T
V
Q
V
N
G
Q
E
Site 32
Y466
Q
V
N
G
Q
E
K
Y
L
I
L
C
E
V
G
Site 33
S496
A
C
L
M
F
D
G
S
D
P
K
S
F
A
H
Site 34
S500
F
D
G
S
D
P
K
S
F
A
H
C
A
S
V
Site 35
Y512
A
S
V
Y
K
H
H
Y
M
D
G
Q
T
P
C
Site 36
T517
H
H
Y
M
D
G
Q
T
P
C
L
F
V
S
S
Site 37
S524
T
P
C
L
F
V
S
S
K
A
D
L
P
E
G
Site 38
S538
G
V
A
V
S
G
P
S
P
A
E
F
C
R
K
Site 39
T565
G
P
A
E
P
S
T
T
I
F
T
Q
L
A
T
Site 40
S587
V
H
A
E
L
H
P
S
S
F
W
L
R
G
L
Site 41
S588
H
A
E
L
H
P
S
S
F
W
L
R
G
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation