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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM20C
Full Name:
Dentin matrix protein 4
Alias:
Protein FAM20C
Type:
Mass (Da):
64446
Number AA:
570
UniProt ID:
Q8IXL6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
E
R
R
G
A
R
P
S
G
E
P
G
C
S
C
Site 2
S33
P
S
G
E
P
G
C
S
C
A
Q
P
A
A
E
Site 3
S60
P
G
E
P
P
A
A
S
S
A
A
G
D
A
G
Site 4
T73
A
G
W
P
N
K
H
T
L
R
I
L
Q
D
F
Site 5
S81
L
R
I
L
Q
D
F
S
S
D
P
S
S
N
L
Site 6
S82
R
I
L
Q
D
F
S
S
D
P
S
S
N
L
S
Site 7
S85
Q
D
F
S
S
D
P
S
S
N
L
S
S
H
S
Site 8
S86
D
F
S
S
D
P
S
S
N
L
S
S
H
S
L
Site 9
S89
S
D
P
S
S
N
L
S
S
H
S
L
E
K
L
Site 10
S90
D
P
S
S
N
L
S
S
H
S
L
E
K
L
P
Site 11
S92
S
S
N
L
S
S
H
S
L
E
K
L
P
P
A
Site 12
S134
R
D
P
G
P
R
R
S
E
S
P
P
G
P
G
Site 13
S136
P
G
P
R
R
S
E
S
P
P
G
P
G
G
D
Site 14
S145
P
G
P
G
G
D
A
S
L
L
A
R
L
F
E
Site 15
S174
D
V
L
F
N
V
N
S
D
T
R
L
S
P
K
Site 16
S179
V
N
S
D
T
R
L
S
P
K
A
A
E
N
P
Site 17
S200
A
E
G
A
E
F
L
S
P
G
E
A
A
V
D
Site 18
S208
P
G
E
A
A
V
D
S
Y
P
N
W
L
K
F
Site 19
Y209
G
E
A
A
V
D
S
Y
P
N
W
L
K
F
H
Site 20
Y222
F
H
I
G
I
N
R
Y
E
L
Y
S
R
H
N
Site 21
Y225
G
I
N
R
Y
E
L
Y
S
R
H
N
P
A
I
Site 22
S226
I
N
R
Y
E
L
Y
S
R
H
N
P
A
I
E
Site 23
S240
E
A
L
L
H
D
L
S
S
Q
R
I
T
S
V
Site 24
T245
D
L
S
S
Q
R
I
T
S
V
A
M
K
S
G
Site 25
S246
L
S
S
Q
R
I
T
S
V
A
M
K
S
G
G
Site 26
T254
V
A
M
K
S
G
G
T
Q
L
K
L
I
M
T
Site 27
T261
T
Q
L
K
L
I
M
T
F
Q
N
Y
G
Q
A
Site 28
T281
K
Q
T
R
E
Q
E
T
P
P
D
F
F
Y
F
Site 29
Y287
E
T
P
P
D
F
F
Y
F
S
D
Y
E
R
H
Site 30
Y291
D
F
F
Y
F
S
D
Y
E
R
H
N
A
E
I
Site 31
T323
A
G
R
M
V
N
M
T
K
E
I
R
D
V
T
Site 32
T330
T
K
E
I
R
D
V
T
R
D
K
K
L
W
R
Site 33
T338
R
D
K
K
L
W
R
T
F
F
I
S
P
A
N
Site 34
Y356
F
Y
G
E
C
S
Y
Y
C
S
T
E
H
A
L
Site 35
S373
K
P
D
Q
I
E
G
S
L
A
A
F
L
P
D
Site 36
S382
A
A
F
L
P
D
L
S
L
A
K
R
K
T
W
Site 37
T388
L
S
L
A
K
R
K
T
W
R
N
P
W
R
R
Site 38
Y397
R
N
P
W
R
R
S
Y
H
K
R
K
K
A
E
Site 39
Y411
E
W
E
V
D
P
D
Y
C
E
E
V
K
Q
T
Site 40
T418
Y
C
E
E
V
K
Q
T
P
P
Y
D
S
S
H
Site 41
Y421
E
V
K
Q
T
P
P
Y
D
S
S
H
R
I
L
Site 42
S424
Q
T
P
P
Y
D
S
S
H
R
I
L
D
V
M
Site 43
Y448
G
N
M
D
R
H
H
Y
E
T
F
E
K
F
G
Site 44
T450
M
D
R
H
H
Y
E
T
F
E
K
F
G
N
E
Site 45
Y472
N
G
R
G
F
G
K
Y
S
H
D
E
L
S
I
Site 46
S473
G
R
G
F
G
K
Y
S
H
D
E
L
S
I
L
Site 47
S478
K
Y
S
H
D
E
L
S
I
L
V
P
L
Q
Q
Site 48
T493
C
C
R
I
R
K
S
T
Y
L
R
L
Q
L
L
Site 49
Y494
C
R
I
R
K
S
T
Y
L
R
L
Q
L
L
A
Site 50
S508
A
K
E
E
Y
K
L
S
L
L
M
A
E
S
L
Site 51
S554
V
E
R
N
G
L
H
S
V
V
D
D
D
L
D
Site 52
T562
V
V
D
D
D
L
D
T
E
H
R
A
A
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation