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Updated November 2019
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Protein Info
Short Name:
FAM178B
Full Name:
Protein FAM178B
Alias:
Type:
Mass (Da):
93514
Number AA:
827
UniProt ID:
Q8IXR5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
Y
E
E
L
K
E
K
S
H
K
P
D
V
E
L
Site 2
S38
A
W
R
I
D
M
V
S
T
E
L
E
S
F
R
Site 3
S43
M
V
S
T
E
L
E
S
F
R
K
A
S
Y
I
Site 4
S48
L
E
S
F
R
K
A
S
Y
I
E
S
G
P
E
Site 5
Y49
E
S
F
R
K
A
S
Y
I
E
S
G
P
E
E
Site 6
S52
R
K
A
S
Y
I
E
S
G
P
E
E
F
Y
Q
Site 7
Y58
E
S
G
P
E
E
F
Y
Q
R
F
K
K
C
F
Site 8
S79
I
S
I
K
G
K
D
S
Q
N
T
A
H
G
Y
Site 9
T92
G
Y
L
I
L
N
R
T
L
H
Q
Q
L
K
I
Site 10
Y128
G
A
L
P
F
P
P
Y
V
A
K
A
S
S
D
Site 11
S133
P
P
Y
V
A
K
A
S
S
D
E
L
L
N
L
Site 12
S134
P
Y
V
A
K
A
S
S
D
E
L
L
N
L
Q
Site 13
S155
L
G
F
V
I
L
R
S
S
Q
N
W
N
S
K
Site 14
S156
G
F
V
I
L
R
S
S
Q
N
W
N
S
K
N
Site 15
S168
S
K
N
R
Q
R
W
S
R
T
K
A
G
Q
M
Site 16
S215
Y
N
L
E
D
G
L
S
D
H
P
L
D
Q
G
Site 17
S232
C
P
A
R
R
P
C
S
P
A
S
A
P
A
P
Site 18
S235
R
R
P
C
S
P
A
S
A
P
A
P
T
S
P
Site 19
S241
A
S
A
P
A
P
T
S
P
K
K
P
K
I
Q
Site 20
T253
K
I
Q
A
P
G
E
T
F
P
T
D
W
S
P
Site 21
T256
A
P
G
E
T
F
P
T
D
W
S
P
P
P
V
Site 22
S259
E
T
F
P
T
D
W
S
P
P
P
V
E
F
L
Site 23
S274
N
P
R
V
L
Q
A
S
R
E
A
P
A
Q
R
Site 24
S326
E
K
L
F
W
N
T
S
G
L
S
Q
Q
A
A
Site 25
S338
Q
A
A
A
P
E
F
S
W
G
G
S
G
S
Y
Site 26
S342
P
E
F
S
W
G
G
S
G
S
Y
F
N
N
L
Site 27
Y345
S
W
G
G
S
G
S
Y
F
N
N
L
D
Y
L
Site 28
Y351
S
Y
F
N
N
L
D
Y
L
L
Q
E
K
R
E
Site 29
T389
D
E
E
E
V
P
L
T
P
E
H
R
M
L
V
Site 30
S400
R
M
L
V
E
K
Y
S
V
S
L
Q
T
I
P
Site 31
T405
K
Y
S
V
S
L
Q
T
I
P
P
V
H
P
G
Site 32
S430
L
P
C
I
L
D
S
S
L
L
K
P
R
S
H
Site 33
S436
S
S
L
L
K
P
R
S
H
L
E
G
L
F
L
Site 34
S444
H
L
E
G
L
F
L
S
S
P
P
A
Q
Q
L
Site 35
S452
S
P
P
A
Q
Q
L
S
F
L
R
S
G
L
L
Site 36
T482
Q
W
L
F
Q
L
L
T
W
P
P
E
T
S
L
Site 37
S527
E
V
R
E
A
F
H
S
L
G
A
H
S
P
A
Site 38
Y536
G
A
H
S
P
A
L
Y
P
L
G
P
F
W
H
Site 39
T665
V
Q
F
F
P
D
M
T
S
R
S
R
R
L
R
Site 40
S666
Q
F
F
P
D
M
T
S
R
S
R
R
L
R
S
Site 41
S668
F
P
D
M
T
S
R
S
R
R
L
R
S
Q
L
Site 42
S673
S
R
S
R
R
L
R
S
Q
L
S
L
V
V
I
Site 43
T697
L
P
L
W
Q
E
K
T
Q
L
S
S
L
S
R
Site 44
S700
W
Q
E
K
T
Q
L
S
S
L
S
R
L
L
G
Site 45
S701
Q
E
K
T
Q
L
S
S
L
S
R
L
L
G
L
Site 46
S703
K
T
Q
L
S
S
L
S
R
L
L
G
L
M
R
Site 47
S712
L
L
G
L
M
R
P
S
S
L
R
Q
Y
L
D
Site 48
S713
L
G
L
M
R
P
S
S
L
R
Q
Y
L
D
S
Site 49
Y717
R
P
S
S
L
R
Q
Y
L
D
S
V
P
L
P
Site 50
S720
S
L
R
Q
Y
L
D
S
V
P
L
P
P
C
Q
Site 51
T762
V
V
S
C
Q
D
I
T
P
D
Q
W
G
E
L
Site 52
S781
M
Q
L
D
R
H
I
S
T
Q
I
R
E
S
P
Site 53
T782
Q
L
D
R
H
I
S
T
Q
I
R
E
S
P
Q
Site 54
S787
I
S
T
Q
I
R
E
S
P
Q
A
M
H
R
T
Site 55
T801
T
M
L
K
D
L
A
T
Q
T
Y
I
R
W
Q
Site 56
Y804
K
D
L
A
T
Q
T
Y
I
R
W
Q
E
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation