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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RBM12B
Full Name:
RNA-binding protein 12B
Alias:
RNA-binding motif protein 12B
Type:
Mass (Da):
118103
Number AA:
1001
UniProt ID:
Q8IXT5
International Prot ID:
IPI00871780
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003676
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T27
R
H
F
F
T
G
L
T
I
P
D
G
G
V
H
Site 2
S58
E
D
A
R
R
A
I
S
R
S
G
G
F
I
K
Site 3
S60
A
R
R
A
I
S
R
S
G
G
F
I
K
D
S
Site 4
S74
S
S
V
E
L
F
L
S
S
K
A
E
M
Q
K
Site 5
T82
S
K
A
E
M
Q
K
T
I
E
M
K
R
T
D
Site 6
T88
K
T
I
E
M
K
R
T
D
R
V
G
R
G
R
Site 7
S98
V
G
R
G
R
P
G
S
G
T
S
G
V
D
S
Site 8
T100
R
G
R
P
G
S
G
T
S
G
V
D
S
L
S
Site 9
S101
G
R
P
G
S
G
T
S
G
V
D
S
L
S
N
Site 10
S105
S
G
T
S
G
V
D
S
L
S
N
F
I
E
S
Site 11
S107
T
S
G
V
D
S
L
S
N
F
I
E
S
V
K
Site 12
S112
S
L
S
N
F
I
E
S
V
K
E
E
A
S
N
Site 13
S118
E
S
V
K
E
E
A
S
N
S
G
Y
G
S
S
Site 14
S120
V
K
E
E
A
S
N
S
G
Y
G
S
S
I
N
Site 15
Y122
E
E
A
S
N
S
G
Y
G
S
S
I
N
Q
D
Site 16
S124
A
S
N
S
G
Y
G
S
S
I
N
Q
D
A
G
Site 17
S125
S
N
S
G
Y
G
S
S
I
N
Q
D
A
G
F
Site 18
T147
G
N
L
R
P
R
K
T
R
P
L
K
A
E
N
Site 19
Y156
P
L
K
A
E
N
P
Y
L
F
L
R
G
L
P
Site 20
S216
G
G
L
K
C
H
R
S
F
M
G
S
R
F
I
Site 21
S250
E
G
D
V
L
R
R
S
E
E
H
S
P
P
R
Site 22
S254
L
R
R
S
E
E
H
S
P
P
R
G
I
N
D
Site 23
S268
D
R
H
F
R
K
R
S
H
S
K
S
P
R
R
Site 24
S270
H
F
R
K
R
S
H
S
K
S
P
R
R
T
R
Site 25
S272
R
K
R
S
H
S
K
S
P
R
R
T
R
S
R
Site 26
T276
H
S
K
S
P
R
R
T
R
S
R
S
P
L
G
Site 27
S278
K
S
P
R
R
T
R
S
R
S
P
L
G
F
Y
Site 28
S280
P
R
R
T
R
S
R
S
P
L
G
F
Y
V
H
Site 29
Y285
S
R
S
P
L
G
F
Y
V
H
L
K
N
L
S
Site 30
S292
Y
V
H
L
K
N
L
S
L
S
I
D
E
R
D
Site 31
S294
H
L
K
N
L
S
L
S
I
D
E
R
D
L
R
Site 32
T307
L
R
N
F
F
R
G
T
D
L
T
D
E
Q
I
Site 33
T310
F
F
R
G
T
D
L
T
D
E
Q
I
R
F
L
Site 34
Y318
D
E
Q
I
R
F
L
Y
K
D
E
N
R
T
R
Site 35
Y326
K
D
E
N
R
T
R
Y
A
F
V
M
F
K
T
Site 36
Y337
M
F
K
T
L
K
D
Y
N
T
A
L
S
L
H
Site 37
T339
K
T
L
K
D
Y
N
T
A
L
S
L
H
K
T
Site 38
S342
K
D
Y
N
T
A
L
S
L
H
K
T
V
L
Q
Site 39
Y350
L
H
K
T
V
L
Q
Y
R
P
V
H
I
D
P
Site 40
S359
P
V
H
I
D
P
I
S
R
K
Q
M
L
K
F
Site 41
Y370
M
L
K
F
I
A
R
Y
E
K
K
R
S
G
S
Site 42
S375
A
R
Y
E
K
K
R
S
G
S
L
E
R
D
R
Site 43
S377
Y
E
K
K
R
S
G
S
L
E
R
D
R
P
G
Site 44
S387
R
D
R
P
G
H
V
S
Q
K
Y
S
Q
E
G
Site 45
Y390
P
G
H
V
S
Q
K
Y
S
Q
E
G
N
S
G
Site 46
S391
G
H
V
S
Q
K
Y
S
Q
E
G
N
S
G
Q
Site 47
Y403
S
G
Q
K
L
C
I
Y
I
R
N
F
P
F
D
Site 48
T412
R
N
F
P
F
D
V
T
K
V
E
V
Q
K
F
Site 49
Y431
L
L
A
E
D
D
I
Y
L
L
Y
D
D
K
G
Site 50
Y434
E
D
D
I
Y
L
L
Y
D
D
K
G
V
G
L
Site 51
S450
E
A
L
V
K
F
K
S
E
E
Q
A
M
K
A
Site 52
S488
Q
E
F
G
V
N
F
S
V
M
S
S
E
K
M
Site 53
S492
V
N
F
S
V
M
S
S
E
K
M
Q
A
R
S
Site 54
S499
S
E
K
M
Q
A
R
S
Q
S
R
E
R
G
D
Site 55
S501
K
M
Q
A
R
S
Q
S
R
E
R
G
D
H
S
Site 56
S508
S
R
E
R
G
D
H
S
H
L
F
D
S
K
D
Site 57
S513
D
H
S
H
L
F
D
S
K
D
P
P
I
Y
S
Site 58
Y519
D
S
K
D
P
P
I
Y
S
V
G
A
F
E
N
Site 59
S520
S
K
D
P
P
I
Y
S
V
G
A
F
E
N
F
Site 60
S561
P
P
E
D
F
R
H
S
S
E
D
F
R
F
P
Site 61
S562
P
E
D
F
R
H
S
S
E
D
F
R
F
P
P
Site 62
S575
P
P
E
D
F
R
H
S
P
E
D
F
R
R
P
Site 63
S591
E
E
D
F
R
R
P
S
E
E
D
F
R
R
P
Site 64
S638
L
E
E
D
F
R
R
S
P
T
E
D
F
R
Q
Site 65
T640
E
D
F
R
R
S
P
T
E
D
F
R
Q
L
P
Site 66
S710
P
E
E
D
F
R
H
S
P
E
E
D
F
R
Q
Site 67
S718
P
E
E
D
F
R
Q
S
P
Q
E
H
F
R
R
Site 68
S798
P
Q
E
H
F
R
R
S
R
E
E
D
F
R
H
Site 69
S829
P
P
D
E
D
F
R
S
P
Q
E
E
D
F
R
Site 70
S839
E
E
D
F
R
C
P
S
D
E
D
F
R
Q
L
Site 71
S874
P
P
G
E
D
F
R
S
P
P
D
D
F
R
S
Site 72
S881
S
P
P
D
D
F
R
S
H
R
P
F
V
N
F
Site 73
S921
D
P
K
I
N
C
G
S
G
R
V
T
P
I
K
Site 74
Y948
I
L
D
F
F
H
G
Y
R
I
I
P
D
S
V
Site 75
S954
G
Y
R
I
I
P
D
S
V
S
I
Q
Y
N
E
Site 76
S956
R
I
I
P
D
S
V
S
I
Q
Y
N
E
Q
G
Site 77
Y959
P
D
S
V
S
I
Q
Y
N
E
Q
G
L
P
T
Site 78
Y976
A
I
V
A
M
I
N
Y
N
E
A
M
A
A
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation