PhosphoNET

           
Protein Info 
   
Short Name:  SP8
Full Name:  Transcription factor Sp8
Alias:  BTD; Specificity 8; Transcription factor Sp8
Type: 
Mass (Da):  50500
Number AA:  508
UniProt ID:  Q8IXZ3
International Prot ID:  IPI00377223
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0003677  GO:0008270   PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S14GEEPRLGSTPLAMLA
Site 2T23PLAMLAATCNKIGSP
Site 3S29ATCNKIGSPSPSPSS
Site 4S31CNKIGSPSPSPSSLS
Site 5S33KIGSPSPSPSSLSDS
Site 6S35GSPSPSPSSLSDSSS
Site 7S36SPSPSPSSLSDSSSS
Site 8S38SPSPSSLSDSSSSFG
Site 9S40SPSSLSDSSSSFGKG
Site 10S41PSSLSDSSSSFGKGF
Site 11S42SSLSDSSSSFGKGFH
Site 12S43SLSDSSSSFGKGFHP
Site 13S54GFHPWKRSSSSSSAS
Site 14S55FHPWKRSSSSSSASC
Site 15S56HPWKRSSSSSSASCN
Site 16S57PWKRSSSSSSASCNV
Site 17S58WKRSSSSSSASCNVV
Site 18S59KRSSSSSSASCNVVG
Site 19S61SSSSSSASCNVVGSS
Site 20S70NVVGSSLSSFGVSGA
Site 21S71VVGSSLSSFGVSGAS
Site 22S75SLSSFGVSGASRNGG
Site 23S78SFGVSGASRNGGSSS
Site 24S84ASRNGGSSSAAAAAA
Site 25S85SRNGGSSSAAAAAAA
Site 26S110DSFSCGGSPGSSAFS
Site 27S113SCGGSPGSSAFSLTS
Site 28S114CGGSPGSSAFSLTSS
Site 29S117SPGSSAFSLTSSSAA
Site 30S137AAAAASSSPFANDYS
Site 31Y143SSPFANDYSVFQAPG
Site 32S144SPFANDYSVFQAPGV
Site 33S166GGGGGGGSSAHSQDG
Site 34S167GGGGGGSSAHSQDGS
Site 35S170GGGSSAHSQDGSHQP
Site 36S174SAHSQDGSHQPVFIS
Site 37Y203RVGMAHPYESWFKPS
Site 38S210YESWFKPSHPGLGAA
Site 39S222GAAGEVGSAGASSWW
Site 40S226EVGSAGASSWWDVGA
Site 41S243IDVQNPNSAAALPGS
Site 42T260PAAGGLQTSLHSPLG
Site 43S264GLQTSLHSPLGGYNS
Site 44Y269LHSPLGGYNSDYSGL
Site 45S271SPLGGYNSDYSGLSH
Site 46Y273LGGYNSDYSGLSHSA
Site 47S274GGYNSDYSGLSHSAF
Site 48S277NSDYSGLSHSAFSSG
Site 49S279DYSGLSHSAFSSGAS
Site 50S282GLSHSAFSSGASSHL
Site 51S291GASSHLLSPAGQHLM
Site 52S308FKPVLPGSYPDSAPS
Site 53Y309KPVLPGSYPDSAPSP
Site 54S312LPGSYPDSAPSPLAG
Site 55S315SYPDSAPSPLAGAGG
Site 56S336PSAPLGGSPRSSARR
Site 57S339PLGGSPRSSARRYSG
Site 58S340LGGSPRSSARRYSGR
Site 59Y344PRSSARRYSGRATCD
Site 60S345RSSARRYSGRATCDC
Site 61S367RLGPAGASLRRKGLH
Site 62S375LRRKGLHSCHIPGCG
Site 63Y385IPGCGKVYGKTSHLK
Site 64S389GKVYGKTSHLKAHLR
Site 65T399KAHLRWHTGERPFVC
Site 66T416LFCGKRFTRSDELQR
Site 67S418CGKRFTRSDELQRHL
Site 68T429QRHLRTHTGEKRFAC
Site 69S450FMRSDHLSKHVKTHS
Site 70T455HLSKHVKTHSGGGGG
Site 71S457SKHVKTHSGGGGGGG
Site 72S465GGGGGGGSAGSGSGG
Site 73S468GGGGSAGSGSGGKKG
Site 74S470GGSAGSGSGGKKGSD
Site 75S476GSGGKKGSDTDSEHS
Site 76T478GGKKGSDTDSEHSAA
Site 77S480KKGSDTDSEHSAAGS
Site 78S483SDTDSEHSAAGSPPC
Site 79S487SEHSAAGSPPCHSPE
Site 80S492AGSPPCHSPELLQPP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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