PhosphoNET

           
Protein Info 
   
Short Name:  PPAPDC2
Full Name:  Presqualene diphosphate phosphatase
Alias:  BA6J24.6; EC 3.1.3.-; FLJ46512; FLJ90191; MGC15483; Phosphatidic acid phosphatase type 2 domain containing 2; PPAC2; Presqualene diphosphate phosphatase
Type:  Phosphatase; EC 3.1.3.-
Mass (Da):  32194
Number AA:  295
UniProt ID:  Q8IY26
International Prot ID:  IPI00647930
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:  GO:0016787     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7_MPSPRRSMEGRPLG
Site 2S16EGRPLGVSASSSSSS
Site 3S18RPLGVSASSSSSSPG
Site 4S19PLGVSASSSSSSPGS
Site 5S20LGVSASSSSSSPGSP
Site 6S21GVSASSSSSSPGSPA
Site 7S22VSASSSSSSPGSPAH
Site 8S23SASSSSSSPGSPAHG
Site 9S26SSSSSPGSPAHGGGG
Site 10S36HGGGGGGSRFEFQSL
Site 11S42GSRFEFQSLLSSRAT
Site 12S46EFQSLLSSRATAVDP
Site 13S61TCARLRASESPVHRR
Site 14S63ARLRASESPVHRRGS
Site 15S70SPVHRRGSFPLAAAG
Site 16S79PLAAAGPSQSPAPPL
Site 17S81AAAGPSQSPAPPLPE
Site 18S97DRMDLNPSFLGIALR
Site 19S124LGVCAGESSSWGSVR
Site 20S125GVCAGESSSWGSVRP
Site 21S126VCAGESSSWGSVRPL
Site 22S129GESSSWGSVRPLMKL
Site 23S159YCLCRSDSWAGREVL
Site 24T202NQMDMFVTLSVDKYS
Site 25Y208VTLSVDKYSFPSGHA
Site 26S209TLSVDKYSFPSGHAT
Site 27T216SFPSGHATRAALMSR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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