KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
MICALL2
Full Name:
MICAL-like protein 2
Alias:
JRAB; Junctional Rab13-binding; MICAL-L2; MICAL-like 2; MILK2
Type:
Adhesion; Cytoskeleton protein
Mass (Da):
97502
Number AA:
904
UniProt ID:
Q8IY33
International Prot ID:
IPI00217622
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y59
A
L
K
K
E
N
I
Y
E
N
N
K
L
A
F
Site 2
T97
P
D
R
L
S
I
L
T
Y
V
S
Q
Y
Y
N
Site 3
Y98
D
R
L
S
I
L
T
Y
V
S
Q
Y
Y
N
Y
Site 4
S100
L
S
I
L
T
Y
V
S
Q
Y
Y
N
Y
F
H
Site 5
Y102
I
L
T
Y
V
S
Q
Y
Y
N
Y
F
H
G
R
Site 6
Y103
L
T
Y
V
S
Q
Y
Y
N
Y
F
H
G
R
S
Site 7
Y105
Y
V
S
Q
Y
Y
N
Y
F
H
G
R
S
P
I
Site 8
S110
Y
N
Y
F
H
G
R
S
P
I
G
G
M
A
G
Site 9
S122
M
A
G
V
K
R
A
S
E
D
S
E
E
E
P
Site 10
S125
V
K
R
A
S
E
D
S
E
E
E
P
S
G
K
Site 11
S130
E
D
S
E
E
E
P
S
G
K
K
A
P
V
Q
Site 12
S143
V
Q
A
A
K
L
P
S
P
A
P
A
R
K
P
Site 13
S153
P
A
R
K
P
P
L
S
P
A
Q
T
N
P
V
Site 14
T157
P
P
L
S
P
A
Q
T
N
P
V
V
Q
R
R
Site 15
T175
A
G
G
P
P
P
K
T
D
Q
A
L
A
G
S
Site 16
Y208
H
L
A
D
G
R
L
Y
H
R
S
C
F
R
C
Site 17
T230
H
S
G
A
Y
K
A
T
G
E
P
G
T
F
V
Site 18
T235
K
A
T
G
E
P
G
T
F
V
C
T
S
H
L
Site 19
S247
S
H
L
P
A
A
A
S
A
S
P
K
L
T
G
Site 20
S249
L
P
A
A
A
S
A
S
P
K
L
T
G
L
V
Site 21
T253
A
S
A
S
P
K
L
T
G
L
V
P
R
Q
P
Site 22
S267
P
G
A
M
G
V
D
S
R
T
S
C
S
P
Q
Site 23
T269
A
M
G
V
D
S
R
T
S
C
S
P
Q
K
A
Site 24
S270
M
G
V
D
S
R
T
S
C
S
P
Q
K
A
Q
Site 25
S272
V
D
S
R
T
S
C
S
P
Q
K
A
Q
E
A
Site 26
S285
E
A
N
K
A
R
P
S
A
W
E
P
A
A
G
Site 27
S294
W
E
P
A
A
G
N
S
P
A
R
A
S
V
P
Site 28
S299
G
N
S
P
A
R
A
S
V
P
A
A
P
N
P
Site 29
S318
A
T
S
V
H
V
R
S
P
A
R
P
S
E
S
Site 30
S323
V
R
S
P
A
R
P
S
E
S
R
L
A
P
T
Site 31
T330
S
E
S
R
L
A
P
T
P
T
E
G
K
V
R
Site 32
T341
G
K
V
R
P
R
V
T
N
S
S
P
M
G
W
Site 33
S343
V
R
P
R
V
T
N
S
S
P
M
G
W
S
S
Site 34
S344
R
P
R
V
T
N
S
S
P
M
G
W
S
S
A
Site 35
S350
S
S
P
M
G
W
S
S
A
A
P
C
T
A
A
Site 36
T355
W
S
S
A
A
P
C
T
A
A
A
A
S
H
P
Site 37
S367
S
H
P
A
V
P
P
S
A
P
D
P
R
P
A
Site 38
T375
A
P
D
P
R
P
A
T
P
Q
G
G
G
A
P
Site 39
T389
P
R
V
A
A
P
Q
T
T
L
S
S
S
S
T
Site 40
T390
R
V
A
A
P
Q
T
T
L
S
S
S
S
T
S
Site 41
S392
A
A
P
Q
T
T
L
S
S
S
S
T
S
A
A
Site 42
S393
A
P
Q
T
T
L
S
S
S
S
T
S
A
A
T
Site 43
T396
T
T
L
S
S
S
S
T
S
A
A
T
V
D
P
Site 44
S397
T
L
S
S
S
S
T
S
A
A
T
V
D
P
P
Site 45
T400
S
S
S
T
S
A
A
T
V
D
P
P
A
W
T
Site 46
T407
T
V
D
P
P
A
W
T
P
S
A
S
R
T
Q
Site 47
S409
D
P
P
A
W
T
P
S
A
S
R
T
Q
Q
A
Site 48
T413
W
T
P
S
A
S
R
T
Q
Q
A
R
N
K
F
Site 49
T423
A
R
N
K
F
F
Q
T
S
A
V
P
P
G
T
Site 50
S424
R
N
K
F
F
Q
T
S
A
V
P
P
G
T
S
Site 51
S431
S
A
V
P
P
G
T
S
L
S
G
R
G
P
T
Site 52
S433
V
P
P
G
T
S
L
S
G
R
G
P
T
P
S
Site 53
T438
S
L
S
G
R
G
P
T
P
S
L
V
L
S
K
Site 54
S440
S
G
R
G
P
T
P
S
L
V
L
S
K
D
S
Site 55
S444
P
T
P
S
L
V
L
S
K
D
S
S
K
E
Q
Site 56
S448
L
V
L
S
K
D
S
S
K
E
Q
A
R
N
F
Site 57
S475
A
P
A
P
G
R
P
S
P
A
T
A
A
V
P
Site 58
T478
P
G
R
P
S
P
A
T
A
A
V
P
S
S
Q
Site 59
S484
A
T
A
A
V
P
S
S
Q
P
K
T
E
A
P
Site 60
T488
V
P
S
S
Q
P
K
T
E
A
P
Q
A
S
P
Site 61
S494
K
T
E
A
P
Q
A
S
P
L
A
K
P
L
Q
Site 62
S502
P
L
A
K
P
L
Q
S
S
S
P
R
V
L
G
Site 63
S504
A
K
P
L
Q
S
S
S
P
R
V
L
G
L
P
Site 64
S512
P
R
V
L
G
L
P
S
R
M
E
P
P
A
P
Site 65
S521
M
E
P
P
A
P
L
S
T
S
S
T
S
Q
A
Site 66
T522
E
P
P
A
P
L
S
T
S
S
T
S
Q
A
S
Site 67
S524
P
A
P
L
S
T
S
S
T
S
Q
A
S
A
L
Site 68
T525
A
P
L
S
T
S
S
T
S
Q
A
S
A
L
P
Site 69
S526
P
L
S
T
S
S
T
S
Q
A
S
A
L
P
P
Site 70
S529
T
S
S
T
S
Q
A
S
A
L
P
P
A
G
R
Site 71
S542
G
R
R
N
L
A
E
S
S
G
V
G
R
V
G
Site 72
S552
V
G
R
V
G
A
G
S
R
P
K
P
E
A
P
Site 73
S565
A
P
M
A
K
G
K
S
T
T
L
T
Q
D
M
Site 74
T569
K
G
K
S
T
T
L
T
Q
D
M
S
T
S
L
Site 75
S573
T
T
L
T
Q
D
M
S
T
S
L
Q
E
G
Q
Site 76
S575
L
T
Q
D
M
S
T
S
L
Q
E
G
Q
E
D
Site 77
S598
L
K
P
V
D
R
R
S
P
A
E
R
T
L
K
Site 78
T603
R
R
S
P
A
E
R
T
L
K
P
K
E
P
R
Site 79
S625
G
E
A
P
R
K
V
S
G
S
F
A
G
S
V
Site 80
S627
A
P
R
K
V
S
G
S
F
A
G
S
V
H
I
Site 81
T635
F
A
G
S
V
H
I
T
L
T
P
V
R
P
D
Site 82
T637
G
S
V
H
I
T
L
T
P
V
R
P
D
R
T
Site 83
T644
T
P
V
R
P
D
R
T
P
R
P
A
S
P
G
Site 84
S649
D
R
T
P
R
P
A
S
P
G
P
S
L
P
A
Site 85
S653
R
P
A
S
P
G
P
S
L
P
A
R
S
P
S
Site 86
S658
G
P
S
L
P
A
R
S
P
S
P
P
R
R
R
Site 87
S660
S
L
P
A
R
S
P
S
P
P
R
R
R
R
L
Site 88
S672
R
R
L
A
V
P
A
S
L
D
V
C
D
N
W
Site 89
S693
G
Q
E
A
R
V
Q
S
W
K
E
E
E
K
K
Site 90
S712
G
K
P
G
R
P
L
S
P
A
N
V
P
A
L
Site 91
S726
L
P
G
E
T
V
T
S
P
V
R
L
H
P
D
Site 92
Y734
P
V
R
L
H
P
D
Y
L
S
P
E
E
I
Q
Site 93
S736
R
L
H
P
D
Y
L
S
P
E
E
I
Q
R
Q
Site 94
S796
Q
L
L
L
R
Q
E
S
E
L
M
Y
K
S
K
Site 95
Y800
R
Q
E
S
E
L
M
Y
K
S
K
A
Q
R
L
Site 96
S802
E
S
E
L
M
Y
K
S
K
A
Q
R
L
E
E
Site 97
S830
A
K
P
E
A
L
K
S
L
Q
E
R
R
R
E
Site 98
Y844
E
Q
E
L
L
E
Q
Y
V
S
T
V
N
D
R
Site 99
S846
E
L
L
E
Q
Y
V
S
T
V
N
D
R
S
D
Site 100
T847
L
L
E
Q
Y
V
S
T
V
N
D
R
S
D
I
Site 101
S852
V
S
T
V
N
D
R
S
D
I
V
D
S
L
D
Site 102
S857
D
R
S
D
I
V
D
S
L
D
E
D
R
L
R
Site 103
S886
L
G
L
Q
R
K
K
S
K
F
R
L
S
K
I
Site 104
S891
K
K
S
K
F
R
L
S
K
I
W
S
P
K
S
Site 105
S895
F
R
L
S
K
I
W
S
P
K
S
K
S
S
P
Site 106
S898
S
K
I
W
S
P
K
S
K
S
S
P
S
Q
_
Site 107
S900
I
W
S
P
K
S
K
S
S
P
S
Q
_
_
_
Site 108
S901
W
S
P
K
S
K
S
S
P
S
Q
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation