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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FTSJ3
Full Name:
Putative rRNA methyltransferase 3
Alias:
Putative rRNA methyltransferase 3: rRNA (uridine-2'-O-)-methyltransferase 3; rRNA (uridine-2'-O-)-methyltransferase 3
Type:
EC 2.1.1.-; Methyltransferase
Mass (Da):
96576
Number AA:
847
UniProt ID:
Q8IY81
International Prot ID:
IPI00217686
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0008168
GO:0003676
GO:0016740
PhosphoSite+
KinaseNET
Biological Process:
GO:0031167
GO:0006364
GO:0006396
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
K
K
G
K
V
G
K
S
R
R
D
K
F
Y
H
Site 2
Y16
K
S
R
R
D
K
F
Y
H
L
A
K
E
T
G
Site 3
Y24
H
L
A
K
E
T
G
Y
R
S
R
S
A
F
K
Site 4
S28
E
T
G
Y
R
S
R
S
A
F
K
L
I
Q
L
Site 5
T94
V
T
L
Q
E
D
I
T
T
E
R
C
R
Q
A
Site 6
T95
T
L
Q
E
D
I
T
T
E
R
C
R
Q
A
L
Site 7
S125
G
A
P
N
V
G
A
S
W
V
H
D
A
Y
S
Site 8
Y131
A
S
W
V
H
D
A
Y
S
Q
A
H
L
T
L
Site 9
Y164
K
V
F
R
S
R
D
Y
Q
P
L
L
W
I
F
Site 10
T181
L
F
R
R
V
Q
A
T
K
P
Q
A
S
R
H
Site 11
S186
Q
A
T
K
P
Q
A
S
R
H
E
S
A
E
I
Site 12
S190
P
Q
A
S
R
H
E
S
A
E
I
F
V
V
C
Site 13
T226
E
V
E
V
Q
A
K
T
V
T
E
L
V
T
K
Site 14
T228
E
V
Q
A
K
T
V
T
E
L
V
T
K
K
K
Site 15
T232
K
T
V
T
E
L
V
T
K
K
K
P
K
A
E
Site 16
Y241
K
K
P
K
A
E
G
Y
A
E
G
D
L
T
L
Site 17
T247
G
Y
A
E
G
D
L
T
L
Y
H
R
T
S
V
Site 18
Y249
A
E
G
D
L
T
L
Y
H
R
T
S
V
T
D
Site 19
S253
L
T
L
Y
H
R
T
S
V
T
D
F
L
R
A
Site 20
S307
L
G
R
K
E
L
R
S
L
L
N
W
R
T
K
Site 21
T313
R
S
L
L
N
W
R
T
K
L
R
R
Y
V
A
Site 22
Y318
W
R
T
K
L
R
R
Y
V
A
K
K
L
K
E
Site 23
S333
Q
A
K
A
L
D
I
S
L
S
S
G
E
E
D
Site 24
S335
K
A
L
D
I
S
L
S
S
G
E
E
D
E
G
Site 25
S336
A
L
D
I
S
L
S
S
G
E
E
D
E
G
D
Site 26
S347
D
E
G
D
E
E
D
S
T
A
G
T
T
K
Q
Site 27
T348
E
G
D
E
E
D
S
T
A
G
T
T
K
Q
P
Site 28
T351
E
E
D
S
T
A
G
T
T
K
Q
P
S
K
E
Site 29
T352
E
D
S
T
A
G
T
T
K
Q
P
S
K
E
E
Site 30
S356
A
G
T
T
K
Q
P
S
K
E
E
E
E
E
E
Site 31
T371
E
E
E
Q
L
N
Q
T
L
A
E
M
K
A
Q
Site 32
S422
E
G
E
T
G
M
F
S
L
C
T
I
R
G
H
Site 33
T425
T
G
M
F
S
L
C
T
I
R
G
H
Q
L
L
Site 34
S441
E
V
T
Q
G
D
M
S
A
A
D
T
F
L
S
Site 35
T445
G
D
M
S
A
A
D
T
F
L
S
D
L
P
R
Site 36
S448
S
A
A
D
T
F
L
S
D
L
P
R
D
D
I
Site 37
Y456
D
L
P
R
D
D
I
Y
V
S
D
V
E
D
D
Site 38
S458
P
R
D
D
I
Y
V
S
D
V
E
D
D
G
D
Site 39
T467
V
E
D
D
G
D
D
T
S
L
D
S
D
L
D
Site 40
S468
E
D
D
G
D
D
T
S
L
D
S
D
L
D
P
Site 41
S471
G
D
D
T
S
L
D
S
D
L
D
P
E
E
L
Site 42
T496
D
Q
K
R
M
R
L
T
E
V
Q
D
D
K
E
Site 43
S531
E
Q
A
N
L
W
F
S
K
G
S
F
A
G
I
Site 44
S534
N
L
W
F
S
K
G
S
F
A
G
I
E
D
D
Site 45
S549
A
D
E
A
L
E
I
S
Q
A
Q
L
L
F
E
Site 46
T573
Q
K
Q
Q
L
P
Q
T
P
P
S
C
L
K
T
Site 47
S576
Q
L
P
Q
T
P
P
S
C
L
K
T
E
I
M
Site 48
T580
T
P
P
S
C
L
K
T
E
I
M
S
P
L
Y
Site 49
S584
C
L
K
T
E
I
M
S
P
L
Y
Q
D
E
A
Site 50
Y587
T
E
I
M
S
P
L
Y
Q
D
E
A
P
K
G
Site 51
S599
P
K
G
T
E
A
S
S
G
T
E
A
A
T
G
Site 52
T605
S
S
G
T
E
A
A
T
G
L
E
G
E
E
K
Site 53
S616
G
E
E
K
D
G
I
S
D
S
D
S
S
T
S
Site 54
S618
E
K
D
G
I
S
D
S
D
S
S
T
S
S
E
Site 55
S620
D
G
I
S
D
S
D
S
S
T
S
S
E
E
E
Site 56
S621
G
I
S
D
S
D
S
S
T
S
S
E
E
E
E
Site 57
T622
I
S
D
S
D
S
S
T
S
S
E
E
E
E
S
Site 58
S623
S
D
S
D
S
S
T
S
S
E
E
E
E
S
W
Site 59
S624
D
S
D
S
S
T
S
S
E
E
E
E
S
W
E
Site 60
S629
T
S
S
E
E
E
E
S
W
E
P
L
R
G
K
Site 61
S639
P
L
R
G
K
K
R
S
R
G
P
K
S
D
D
Site 62
S644
K
R
S
R
G
P
K
S
D
D
D
G
F
E
I
Site 63
S676
A
L
G
A
V
I
A
S
S
K
K
A
K
R
D
Site 64
S677
L
G
A
V
I
A
S
S
K
K
A
K
R
D
L
Site 65
S688
K
R
D
L
I
D
N
S
F
N
R
Y
T
F
N
Site 66
Y692
I
D
N
S
F
N
R
Y
T
F
N
E
D
E
G
Site 67
T693
D
N
S
F
N
R
Y
T
F
N
E
D
E
G
E
Site 68
Y727
G
K
K
E
V
E
H
Y
R
K
R
W
R
E
I
Site 69
T770
K
A
E
A
V
V
N
T
V
D
I
S
E
R
E
Site 70
S774
V
V
N
T
V
D
I
S
E
R
E
K
V
A
Q
Site 71
S784
E
K
V
A
Q
L
R
S
L
Y
K
K
A
G
L
Site 72
Y786
V
A
Q
L
R
S
L
Y
K
K
A
G
L
G
K
Site 73
T799
G
K
E
K
R
H
V
T
Y
V
V
A
K
K
G
Site 74
Y800
K
E
K
R
H
V
T
Y
V
V
A
K
K
G
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation