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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NIM1
Full Name:
Serine/threonine-protein kinase NIM1
Alias:
EC 2.7.11.1; MGC42105
Type:
Protein-serine kinase, CAMK group, CAMKL family, NIM1 subfamily
Mass (Da):
49606
Number AA:
436
UniProt ID:
Q8IY84
International Prot ID:
IPI00217690
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0000287
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0006468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
G
G
L
V
N
P
H
Y
A
R
W
D
R
R
D
Site 2
S24
A
R
W
D
R
R
D
S
V
E
S
G
C
Q
T
Site 3
S27
D
R
R
D
S
V
E
S
G
C
Q
T
E
S
S
Site 4
T31
S
V
E
S
G
C
Q
T
E
S
S
K
E
G
E
Site 5
S34
S
G
C
Q
T
E
S
S
K
E
G
E
E
G
Q
Site 6
T46
E
G
Q
P
R
Q
L
T
P
F
E
K
L
T
Q
Site 7
T52
L
T
P
F
E
K
L
T
Q
D
M
S
Q
D
E
Site 8
S56
E
K
L
T
Q
D
M
S
Q
D
E
K
V
V
R
Site 9
T66
E
K
V
V
R
E
I
T
L
G
K
R
I
G
F
Site 10
Y74
L
G
K
R
I
G
F
Y
R
I
R
G
E
I
G
Site 11
S82
R
I
R
G
E
I
G
S
G
N
F
S
Q
V
K
Site 12
S86
E
I
G
S
G
N
F
S
Q
V
K
L
G
I
H
Site 13
T108
A
I
K
I
L
D
K
T
K
L
D
Q
K
T
Q
Site 14
T114
K
T
K
L
D
Q
K
T
Q
R
L
L
S
R
E
Site 15
S119
Q
K
T
Q
R
L
L
S
R
E
I
S
S
M
E
Site 16
S123
R
L
L
S
R
E
I
S
S
M
E
K
L
H
H
Site 17
S124
L
L
S
R
E
I
S
S
M
E
K
L
H
H
P
Site 18
S163
G
E
L
F
G
K
I
S
T
E
G
K
L
S
E
Site 19
S169
I
S
T
E
G
K
L
S
E
P
E
S
K
L
I
Site 20
S173
G
K
L
S
E
P
E
S
K
L
I
F
S
Q
I
Site 21
Y204
L
K
A
E
N
V
F
Y
T
S
N
T
C
V
K
Site 22
T219
V
G
D
F
G
F
S
T
V
S
K
K
G
E
M
Site 23
S221
D
F
G
F
S
T
V
S
K
K
G
E
M
L
N
Site 24
T229
K
K
G
E
M
L
N
T
F
C
G
S
P
P
Y
Site 25
S233
M
L
N
T
F
C
G
S
P
P
Y
A
A
P
E
Site 26
Y236
T
F
C
G
S
P
P
Y
A
A
P
E
L
F
R
Site 27
Y247
E
L
F
R
D
E
H
Y
I
G
I
Y
V
D
I
Site 28
T275
T
M
P
F
R
A
E
T
V
A
K
L
K
K
S
Site 29
S282
T
V
A
K
L
K
K
S
I
L
E
G
T
Y
S
Site 30
T287
K
K
S
I
L
E
G
T
Y
S
V
P
P
H
V
Site 31
Y288
K
S
I
L
E
G
T
Y
S
V
P
P
H
V
S
Site 32
S289
S
I
L
E
G
T
Y
S
V
P
P
H
V
S
E
Site 33
S295
Y
S
V
P
P
H
V
S
E
P
C
H
R
L
I
Site 34
T311
G
V
L
Q
Q
I
P
T
E
R
Y
G
I
D
C
Site 35
Y330
E
W
M
Q
G
V
P
Y
P
T
P
L
E
P
F
Site 36
T332
M
Q
G
V
P
Y
P
T
P
L
E
P
F
Q
L
Site 37
S345
Q
L
D
P
K
H
L
S
E
T
S
T
L
K
E
Site 38
T349
K
H
L
S
E
T
S
T
L
K
E
E
E
N
E
Site 39
S359
E
E
E
N
E
V
K
S
T
L
E
H
L
G
I
Site 40
T360
E
E
N
E
V
K
S
T
L
E
H
L
G
I
T
Site 41
S382
Q
G
R
D
A
R
S
S
I
T
G
V
Y
R
I
Site 42
S420
E
R
D
L
K
K
G
S
R
V
Y
R
G
I
R
Site 43
Y423
L
K
K
G
S
R
V
Y
R
G
I
R
H
T
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation