KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
MKX
Full Name:
Homeobox protein Mohawk
Alias:
Type:
Mass (Da):
39331
Number AA:
352
UniProt ID:
Q8IYA7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
L
F
E
D
G
G
A
S
E
R
E
R
G
G
R
Site 2
Y30
R
E
R
G
G
R
P
Y
S
G
V
L
D
S
P
Site 3
S31
E
R
G
G
R
P
Y
S
G
V
L
D
S
P
H
Site 4
S36
P
Y
S
G
V
L
D
S
P
H
A
R
P
E
V
Site 5
T62
L
G
L
R
H
R
R
T
G
A
R
Q
N
G
G
Site 6
Y90
R
P
L
K
Q
W
L
Y
K
H
R
D
N
P
Y
Site 7
Y97
Y
K
H
R
D
N
P
Y
P
T
K
T
E
K
I
Site 8
T101
D
N
P
Y
P
T
K
T
E
K
I
L
L
A
L
Site 9
T131
A
R
R
R
L
K
N
T
V
R
Q
P
D
L
S
Site 10
S138
T
V
R
Q
P
D
L
S
W
A
L
R
I
K
L
Site 11
Y146
W
A
L
R
I
K
L
Y
N
K
Y
V
Q
G
N
Site 12
Y149
R
I
K
L
Y
N
K
Y
V
Q
G
N
A
E
R
Site 13
S158
Q
G
N
A
E
R
L
S
V
S
S
D
D
S
C
Site 14
S160
N
A
E
R
L
S
V
S
S
D
D
S
C
S
E
Site 15
S161
A
E
R
L
S
V
S
S
D
D
S
C
S
E
D
Site 16
S164
L
S
V
S
S
D
D
S
C
S
E
D
G
E
N
Site 17
S166
V
S
S
D
D
S
C
S
E
D
G
E
N
P
P
Site 18
T175
D
G
E
N
P
P
R
T
H
M
N
E
G
G
Y
Site 19
Y182
T
H
M
N
E
G
G
Y
N
T
P
V
H
H
P
Site 20
S193
V
H
H
P
V
I
K
S
E
N
S
V
I
K
A
Site 21
S206
K
A
G
V
R
P
E
S
R
A
S
E
D
Y
V
Site 22
S209
V
R
P
E
S
R
A
S
E
D
Y
V
A
P
P
Site 23
Y212
E
S
R
A
S
E
D
Y
V
A
P
P
K
Y
K
Site 24
Y218
D
Y
V
A
P
P
K
Y
K
S
S
L
L
N
R
Site 25
Y226
K
S
S
L
L
N
R
Y
L
N
D
S
L
R
H
Site 26
S230
L
N
R
Y
L
N
D
S
L
R
H
V
M
A
T
Site 27
T237
S
L
R
H
V
M
A
T
N
T
T
M
M
G
K
Site 28
T239
R
H
V
M
A
T
N
T
T
M
M
G
K
T
R
Site 29
S251
K
T
R
Q
R
N
H
S
G
S
F
S
S
N
E
Site 30
S253
R
Q
R
N
H
S
G
S
F
S
S
N
E
F
E
Site 31
S255
R
N
H
S
G
S
F
S
S
N
E
F
E
E
E
Site 32
S265
E
F
E
E
E
L
V
S
P
S
S
S
E
T
E
Site 33
S268
E
E
L
V
S
P
S
S
S
E
T
E
G
N
F
Site 34
S269
E
L
V
S
P
S
S
S
E
T
E
G
N
F
V
Site 35
T271
V
S
P
S
S
S
E
T
E
G
N
F
V
Y
R
Site 36
Y277
E
T
E
G
N
F
V
Y
R
T
D
T
L
E
N
Site 37
T279
E
G
N
F
V
Y
R
T
D
T
L
E
N
G
S
Site 38
T281
N
F
V
Y
R
T
D
T
L
E
N
G
S
N
K
Site 39
S286
T
D
T
L
E
N
G
S
N
K
G
E
S
A
A
Site 40
S291
N
G
S
N
K
G
E
S
A
A
N
R
K
G
P
Site 41
T303
K
G
P
S
K
D
D
T
Y
W
K
E
I
N
A
Site 42
Y304
G
P
S
K
D
D
T
Y
W
K
E
I
N
A
A
Site 43
S329
D
K
L
Q
G
T
T
S
C
I
I
Q
K
S
S
Site 44
S335
T
S
C
I
I
Q
K
S
S
H
I
A
E
V
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation