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Updated November 2019
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Protein Info
Short Name:
SRRM1
Full Name:
Serine/arginine repetitive matrix protein 1
Alias:
MGC39488; Plenty of prolines 101-like; POP101; Ser/Arg-related nuclear matrix protein; Serine/arginine repetitive matrix 1; Serine/arginine repetitive matrix protein 1; SRM160; SRm160; SR-related nuclear matrix protein 160 kDa; SR-related nuclear matrix protein of 160 kDa
Type:
RNA binding protein
Mass (Da):
102335
Number AA:
904
UniProt ID:
Q8IYB3
International Prot ID:
IPI00647720
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016363
GO:0016607
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
D
A
G
F
F
R
G
T
S
A
E
Q
D
N
R
Site 2
S10
A
G
F
F
R
G
T
S
A
E
Q
D
N
R
F
Site 3
S18
A
E
Q
D
N
R
F
S
N
K
Q
K
K
L
L
Site 4
T57
P
W
I
T
K
R
V
T
E
I
L
G
F
E
D
Site 5
S82
L
E
V
K
N
P
D
S
K
M
M
Q
I
N
L
Site 6
S143
I
E
Q
E
K
L
A
S
M
K
K
Q
D
E
D
Site 7
S161
R
D
K
E
E
K
E
S
S
R
E
K
R
E
R
Site 8
S162
D
K
E
E
K
E
S
S
R
E
K
R
E
R
S
Site 9
S169
S
R
E
K
R
E
R
S
R
S
P
R
R
R
K
Site 10
S171
E
K
R
E
R
S
R
S
P
R
R
R
K
S
R
Site 11
S177
R
S
P
R
R
R
K
S
R
S
P
S
P
R
R
Site 12
S179
P
R
R
R
K
S
R
S
P
S
P
R
R
R
S
Site 13
S181
R
R
K
S
R
S
P
S
P
R
R
R
S
S
P
Site 14
S186
S
P
S
P
R
R
R
S
S
P
V
R
R
E
R
Site 15
S187
P
S
P
R
R
R
S
S
P
V
R
R
E
R
K
Site 16
S196
V
R
R
E
R
K
R
S
H
S
R
S
P
R
H
Site 17
S198
R
E
R
K
R
S
H
S
R
S
P
R
H
R
T
Site 18
S200
R
K
R
S
H
S
R
S
P
R
H
R
T
K
S
Site 19
T205
S
R
S
P
R
H
R
T
K
S
R
S
P
S
P
Site 20
S207
S
P
R
H
R
T
K
S
R
S
P
S
P
A
P
Site 21
S209
R
H
R
T
K
S
R
S
P
S
P
A
P
E
K
Site 22
S211
R
T
K
S
R
S
P
S
P
A
P
E
K
K
E
Site 23
T220
A
P
E
K
K
E
K
T
P
E
L
P
E
P
S
Site 24
S227
T
P
E
L
P
E
P
S
V
K
V
K
E
P
S
Site 25
S234
S
V
K
V
K
E
P
S
V
Q
E
A
T
S
T
Site 26
T239
E
P
S
V
Q
E
A
T
S
T
S
D
I
L
K
Site 27
S240
P
S
V
Q
E
A
T
S
T
S
D
I
L
K
V
Site 28
T241
S
V
Q
E
A
T
S
T
S
D
I
L
K
V
P
Site 29
S260
I
P
E
P
K
E
P
S
P
E
K
N
S
K
K
Site 30
S265
E
P
S
P
E
K
N
S
K
K
E
K
E
K
E
Site 31
T274
K
E
K
E
K
E
K
T
R
P
R
S
R
S
R
Site 32
S278
K
E
K
T
R
P
R
S
R
S
R
S
K
S
R
Site 33
S280
K
T
R
P
R
S
R
S
R
S
K
S
R
S
R
Site 34
S282
R
P
R
S
R
S
R
S
K
S
R
S
R
T
R
Site 35
S284
R
S
R
S
R
S
K
S
R
S
R
T
R
S
R
Site 36
S286
R
S
R
S
K
S
R
S
R
T
R
S
R
S
P
Site 37
T288
R
S
K
S
R
S
R
T
R
S
R
S
P
S
H
Site 38
S290
K
S
R
S
R
T
R
S
R
S
P
S
H
T
R
Site 39
S292
R
S
R
T
R
S
R
S
P
S
H
T
R
P
R
Site 40
S294
R
T
R
S
R
S
P
S
H
T
R
P
R
R
R
Site 41
T296
R
S
R
S
P
S
H
T
R
P
R
R
R
H
R
Site 42
S304
R
P
R
R
R
H
R
S
R
S
R
S
Y
S
P
Site 43
S306
R
R
R
H
R
S
R
S
R
S
Y
S
P
R
R
Site 44
S308
R
H
R
S
R
S
R
S
Y
S
P
R
R
R
P
Site 45
Y309
H
R
S
R
S
R
S
Y
S
P
R
R
R
P
S
Site 46
S310
R
S
R
S
R
S
Y
S
P
R
R
R
P
S
P
Site 47
S316
Y
S
P
R
R
R
P
S
P
R
R
R
P
S
P
Site 48
S322
P
S
P
R
R
R
P
S
P
R
R
R
T
P
P
Site 49
T327
R
P
S
P
R
R
R
T
P
P
R
R
M
P
P
Site 50
S341
P
P
P
R
H
R
R
S
R
S
P
V
R
R
R
Site 51
S343
P
R
H
R
R
S
R
S
P
V
R
R
R
R
R
Site 52
S351
P
V
R
R
R
R
R
S
S
A
S
L
S
G
S
Site 53
S352
V
R
R
R
R
R
S
S
A
S
L
S
G
S
S
Site 54
S354
R
R
R
R
S
S
A
S
L
S
G
S
S
S
S
Site 55
S356
R
R
S
S
A
S
L
S
G
S
S
S
S
S
S
Site 56
S358
S
S
A
S
L
S
G
S
S
S
S
S
S
S
S
Site 57
S359
S
A
S
L
S
G
S
S
S
S
S
S
S
S
R
Site 58
S360
A
S
L
S
G
S
S
S
S
S
S
S
S
R
S
Site 59
S361
S
L
S
G
S
S
S
S
S
S
S
S
R
S
R
Site 60
S362
L
S
G
S
S
S
S
S
S
S
S
R
S
R
S
Site 61
S363
S
G
S
S
S
S
S
S
S
S
R
S
R
S
P
Site 62
S364
G
S
S
S
S
S
S
S
S
R
S
R
S
P
P
Site 63
S365
S
S
S
S
S
S
S
S
R
S
R
S
P
P
K
Site 64
S367
S
S
S
S
S
S
R
S
R
S
P
P
K
K
P
Site 65
S369
S
S
S
S
R
S
R
S
P
P
K
K
P
P
K
Site 66
T378
P
K
K
P
P
K
R
T
S
S
P
P
R
K
T
Site 67
S379
K
K
P
P
K
R
T
S
S
P
P
R
K
T
R
Site 68
S380
K
P
P
K
R
T
S
S
P
P
R
K
T
R
R
Site 69
T385
T
S
S
P
P
R
K
T
R
R
L
S
P
S
A
Site 70
S389
P
R
K
T
R
R
L
S
P
S
A
S
P
P
R
Site 71
S391
K
T
R
R
L
S
P
S
A
S
P
P
R
R
R
Site 72
S393
R
R
L
S
P
S
A
S
P
P
R
R
R
H
R
Site 73
S402
P
R
R
R
H
R
P
S
P
P
A
T
P
P
P
Site 74
T406
H
R
P
S
P
P
A
T
P
P
P
K
T
R
H
Site 75
T411
P
A
T
P
P
P
K
T
R
H
S
P
T
P
Q
Site 76
S414
P
P
P
K
T
R
H
S
P
T
P
Q
Q
S
N
Site 77
T416
P
K
T
R
H
S
P
T
P
Q
Q
S
N
R
T
Site 78
S420
H
S
P
T
P
Q
Q
S
N
R
T
R
K
S
R
Site 79
T423
T
P
Q
Q
S
N
R
T
R
K
S
R
V
S
V
Site 80
S426
Q
S
N
R
T
R
K
S
R
V
S
V
S
P
G
Site 81
S429
R
T
R
K
S
R
V
S
V
S
P
G
R
T
S
Site 82
S431
R
K
S
R
V
S
V
S
P
G
R
T
S
G
K
Site 83
T435
V
S
V
S
P
G
R
T
S
G
K
V
T
K
H
Site 84
S436
S
V
S
P
G
R
T
S
G
K
V
T
K
H
K
Site 85
T440
G
R
T
S
G
K
V
T
K
H
K
G
T
E
K
Site 86
T445
K
V
T
K
H
K
G
T
E
K
R
E
S
P
S
Site 87
S450
K
G
T
E
K
R
E
S
P
S
P
A
P
K
P
Site 88
S452
T
E
K
R
E
S
P
S
P
A
P
K
P
R
K
Site 89
S463
K
P
R
K
V
E
L
S
E
S
E
E
D
K
G
Site 90
S465
R
K
V
E
L
S
E
S
E
E
D
K
G
G
K
Site 91
S478
G
K
M
A
A
A
D
S
V
Q
Q
R
R
Q
Y
Site 92
Y485
S
V
Q
Q
R
R
Q
Y
R
R
Q
N
Q
Q
S
Site 93
S492
Y
R
R
Q
N
Q
Q
S
S
S
D
S
G
S
S
Site 94
S493
R
R
Q
N
Q
Q
S
S
S
D
S
G
S
S
S
Site 95
S494
R
Q
N
Q
Q
S
S
S
D
S
G
S
S
S
S
Site 96
S496
N
Q
Q
S
S
S
D
S
G
S
S
S
S
S
E
Site 97
S498
Q
S
S
S
D
S
G
S
S
S
S
S
E
D
E
Site 98
S499
S
S
S
D
S
G
S
S
S
S
S
E
D
E
R
Site 99
S500
S
S
D
S
G
S
S
S
S
S
E
D
E
R
P
Site 100
S501
S
D
S
G
S
S
S
S
S
E
D
E
R
P
K
Site 101
S502
D
S
G
S
S
S
S
S
E
D
E
R
P
K
R
Site 102
S510
E
D
E
R
P
K
R
S
H
V
K
N
G
E
V
Site 103
S524
V
G
R
R
R
R
H
S
P
S
R
S
A
S
P
Site 104
S526
R
R
R
R
H
S
P
S
R
S
A
S
P
S
P
Site 105
S528
R
R
H
S
P
S
R
S
A
S
P
S
P
R
K
Site 106
S530
H
S
P
S
R
S
A
S
P
S
P
R
K
R
Q
Site 107
S532
P
S
R
S
A
S
P
S
P
R
K
R
Q
K
E
Site 108
T540
P
R
K
R
Q
K
E
T
S
P
R
G
R
R
R
Site 109
S541
R
K
R
Q
K
E
T
S
P
R
G
R
R
R
R
Site 110
S549
P
R
G
R
R
R
R
S
P
S
P
P
P
T
R
Site 111
S551
G
R
R
R
R
S
P
S
P
P
P
T
R
R
R
Site 112
T555
R
S
P
S
P
P
P
T
R
R
R
R
S
P
S
Site 113
S560
P
P
T
R
R
R
R
S
P
S
P
A
P
P
P
Site 114
S562
T
R
R
R
R
S
P
S
P
A
P
P
P
R
R
Site 115
T572
P
P
P
R
R
R
R
T
P
T
P
P
P
R
R
Site 116
T574
P
R
R
R
R
T
P
T
P
P
P
R
R
R
T
Site 117
T581
T
P
P
P
R
R
R
T
P
S
P
P
P
R
R
Site 118
S583
P
P
R
R
R
T
P
S
P
P
P
R
R
R
S
Site 119
S590
S
P
P
P
R
R
R
S
P
S
P
R
R
Y
S
Site 120
S592
P
P
R
R
R
S
P
S
P
R
R
Y
S
P
P
Site 121
Y596
R
S
P
S
P
R
R
Y
S
P
P
I
Q
R
R
Site 122
S597
S
P
S
P
R
R
Y
S
P
P
I
Q
R
R
Y
Site 123
Y604
S
P
P
I
Q
R
R
Y
S
P
S
P
P
P
K
Site 124
S605
P
P
I
Q
R
R
Y
S
P
S
P
P
P
K
R
Site 125
S607
I
Q
R
R
Y
S
P
S
P
P
P
K
R
R
T
Site 126
T614
S
P
P
P
K
R
R
T
A
S
P
P
P
P
P
Site 127
S616
P
P
K
R
R
T
A
S
P
P
P
P
P
K
R
Site 128
S626
P
P
P
K
R
R
A
S
P
S
P
P
P
K
R
Site 129
S628
P
K
R
R
A
S
P
S
P
P
P
K
R
R
V
Site 130
S636
P
P
P
K
R
R
V
S
H
S
P
P
P
K
Q
Site 131
S638
P
K
R
R
V
S
H
S
P
P
P
K
Q
R
S
Site 132
S645
S
P
P
P
K
Q
R
S
S
P
V
T
K
R
R
Site 133
S646
P
P
P
K
Q
R
S
S
P
V
T
K
R
R
S
Site 134
T649
K
Q
R
S
S
P
V
T
K
R
R
S
P
S
L
Site 135
S653
S
P
V
T
K
R
R
S
P
S
L
S
S
K
H
Site 136
S655
V
T
K
R
R
S
P
S
L
S
S
K
H
R
K
Site 137
S657
K
R
R
S
P
S
L
S
S
K
H
R
K
G
S
Site 138
S658
R
R
S
P
S
L
S
S
K
H
R
K
G
S
S
Site 139
S664
S
S
K
H
R
K
G
S
S
P
S
R
S
T
R
Site 140
S665
S
K
H
R
K
G
S
S
P
S
R
S
T
R
E
Site 141
S667
H
R
K
G
S
S
P
S
R
S
T
R
E
A
R
Site 142
S669
K
G
S
S
P
S
R
S
T
R
E
A
R
S
P
Site 143
T670
G
S
S
P
S
R
S
T
R
E
A
R
S
P
Q
Site 144
S675
R
S
T
R
E
A
R
S
P
Q
P
N
K
R
H
Site 145
S683
P
Q
P
N
K
R
H
S
P
S
P
R
P
R
A
Site 146
S685
P
N
K
R
H
S
P
S
P
R
P
R
A
P
Q
Site 147
T693
P
R
P
R
A
P
Q
T
S
S
S
P
P
P
V
Site 148
S694
R
P
R
A
P
Q
T
S
S
S
P
P
P
V
R
Site 149
S695
P
R
A
P
Q
T
S
S
S
P
P
P
V
R
R
Site 150
S696
R
A
P
Q
T
S
S
S
P
P
P
V
R
R
G
Site 151
S705
P
P
V
R
R
G
A
S
S
S
P
Q
R
R
Q
Site 152
S706
P
V
R
R
G
A
S
S
S
P
Q
R
R
Q
S
Site 153
S707
V
R
R
G
A
S
S
S
P
Q
R
R
Q
S
P
Site 154
S713
S
S
P
Q
R
R
Q
S
P
S
P
S
T
R
P
Site 155
S715
P
Q
R
R
Q
S
P
S
P
S
T
R
P
I
R
Site 156
S717
R
R
Q
S
P
S
P
S
T
R
P
I
R
R
V
Site 157
T718
R
Q
S
P
S
P
S
T
R
P
I
R
R
V
S
Site 158
S725
T
R
P
I
R
R
V
S
R
T
P
E
P
K
K
Site 159
T727
P
I
R
R
V
S
R
T
P
E
P
K
K
I
K
Site 160
S738
K
K
I
K
K
A
A
S
P
S
P
Q
S
V
R
Site 161
S740
I
K
K
A
A
S
P
S
P
Q
S
V
R
R
V
Site 162
S743
A
A
S
P
S
P
Q
S
V
R
R
V
S
S
S
Site 163
S748
P
Q
S
V
R
R
V
S
S
S
R
S
V
S
G
Site 164
S749
Q
S
V
R
R
V
S
S
S
R
S
V
S
G
S
Site 165
S750
S
V
R
R
V
S
S
S
R
S
V
S
G
S
P
Site 166
S752
R
R
V
S
S
S
R
S
V
S
G
S
P
E
P
Site 167
S754
V
S
S
S
R
S
V
S
G
S
P
E
P
A
A
Site 168
S756
S
S
R
S
V
S
G
S
P
E
P
A
A
K
K
Site 169
S769
K
K
P
P
A
P
P
S
P
V
Q
S
Q
S
P
Site 170
S773
A
P
P
S
P
V
Q
S
Q
S
P
S
T
N
W
Site 171
S775
P
S
P
V
Q
S
Q
S
P
S
T
N
W
S
P
Site 172
S777
P
V
Q
S
Q
S
P
S
T
N
W
S
P
A
V
Site 173
T778
V
Q
S
Q
S
P
S
T
N
W
S
P
A
V
P
Site 174
S781
Q
S
P
S
T
N
W
S
P
A
V
P
V
K
K
Site 175
S791
V
P
V
K
K
A
K
S
P
T
P
S
P
S
P
Site 176
T793
V
K
K
A
K
S
P
T
P
S
P
S
P
P
R
Site 177
S795
K
A
K
S
P
T
P
S
P
S
P
P
R
N
S
Site 178
S797
K
S
P
T
P
S
P
S
P
P
R
N
S
D
Q
Site 179
S802
S
P
S
P
P
R
N
S
D
Q
E
G
G
G
K
Site 180
T846
A
A
A
A
A
A
V
T
P
A
A
I
A
A
A
Site 181
T855
A
A
I
A
A
A
T
T
T
L
A
Q
E
E
P
Site 182
T872
A
P
E
P
K
K
E
T
E
S
E
A
E
D
N
Site 183
S874
E
P
K
K
E
T
E
S
E
A
E
D
N
L
D
Site 184
S894
L
R
E
K
A
L
R
S
M
R
K
A
Q
V
S
Site 185
S901
S
M
R
K
A
Q
V
S
P
Q
S
_
_
_
_
Site 186
S904
K
A
Q
V
S
P
Q
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation