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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF595
Full Name:
Zinc finger protein 595
Alias:
Type:
Mass (Da):
74290
Number AA:
648
UniProt ID:
Q8IYB9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
R
D
V
A
I
E
F
S
P
E
E
W
K
C
L
Site 2
Y29
D
P
A
Q
Q
N
L
Y
R
D
V
M
L
E
N
Site 3
Y37
R
D
V
M
L
E
N
Y
R
N
L
V
S
L
G
Site 4
S42
E
N
Y
R
N
L
V
S
L
G
F
V
I
S
N
Site 5
S79
A
K
P
P
A
I
C
S
P
F
S
Q
D
L
S
Site 6
S82
P
A
I
C
S
P
F
S
Q
D
L
S
P
V
Q
Site 7
S86
S
P
F
S
Q
D
L
S
P
V
Q
G
I
E
D
Site 8
S94
P
V
Q
G
I
E
D
S
F
H
K
L
I
L
K
Site 9
Y103
H
K
L
I
L
K
R
Y
E
K
C
G
H
E
N
Site 10
Y134
K
G
V
N
N
G
V
Y
Q
C
L
S
T
T
Q
Site 11
S155
N
T
C
V
K
V
F
S
K
F
S
N
S
N
K
Site 12
S158
V
K
V
F
S
K
F
S
N
S
N
K
H
K
I
Site 13
S160
V
F
S
K
F
S
N
S
N
K
H
K
I
R
H
Site 14
T168
N
K
H
K
I
R
H
T
G
E
K
P
F
K
C
Site 15
T176
G
E
K
P
F
K
C
T
E
C
G
R
S
F
Y
Site 16
Y183
T
E
C
G
R
S
F
Y
M
S
H
L
T
Q
H
Site 17
S212
C
G
K
A
F
N
R
S
T
S
L
S
K
H
K
Site 18
T213
G
K
A
F
N
R
S
T
S
L
S
K
H
K
R
Site 19
S214
K
A
F
N
R
S
T
S
L
S
K
H
K
R
I
Site 20
S216
F
N
R
S
T
S
L
S
K
H
K
R
I
H
T
Site 21
T223
S
K
H
K
R
I
H
T
G
E
K
P
Y
T
C
Site 22
Y228
I
H
T
G
E
K
P
Y
T
C
E
E
C
G
K
Site 23
T229
H
T
G
E
K
P
Y
T
C
E
E
C
G
K
A
Site 24
S240
C
G
K
A
F
R
R
S
T
V
L
N
E
H
K
Site 25
T241
G
K
A
F
R
R
S
T
V
L
N
E
H
K
K
Site 26
T251
N
E
H
K
K
I
H
T
G
E
K
P
Y
K
C
Site 27
S268
C
G
K
A
F
T
R
S
T
T
L
N
E
H
K
Site 28
T269
G
K
A
F
T
R
S
T
T
L
N
E
H
K
K
Site 29
T270
K
A
F
T
R
S
T
T
L
N
E
H
K
K
I
Site 30
Y284
I
H
T
G
E
K
P
Y
K
C
K
E
C
G
K
Site 31
T297
G
K
A
F
R
W
S
T
S
M
N
E
H
K
N
Site 32
S324
C
G
K
A
F
R
Q
S
R
S
L
N
E
H
K
Site 33
S326
K
A
F
R
Q
S
R
S
L
N
E
H
K
N
I
Site 34
T341
H
T
G
E
K
P
Y
T
C
E
K
C
G
K
A
Site 35
S352
C
G
K
A
F
N
Q
S
S
S
L
I
I
H
R
Site 36
S353
G
K
A
F
N
Q
S
S
S
L
I
I
H
R
S
Site 37
S354
K
A
F
N
Q
S
S
S
L
I
I
H
R
S
I
Site 38
S360
S
S
L
I
I
H
R
S
I
H
S
E
Q
K
L
Site 39
Y368
I
H
S
E
Q
K
L
Y
K
C
E
E
C
G
K
Site 40
T378
E
E
C
G
K
A
F
T
W
S
S
S
L
N
K
Site 41
S380
C
G
K
A
F
T
W
S
S
S
L
N
K
H
K
Site 42
S381
G
K
A
F
T
W
S
S
S
L
N
K
H
K
R
Site 43
S382
K
A
F
T
W
S
S
S
L
N
K
H
K
R
I
Site 44
T391
N
K
H
K
R
I
H
T
G
E
K
P
Y
A
C
Site 45
Y396
I
H
T
G
E
K
P
Y
A
C
E
E
C
G
K
Site 46
Y406
E
E
C
G
K
A
F
Y
R
S
S
H
L
A
K
Site 47
S408
C
G
K
A
F
Y
R
S
S
H
L
A
K
H
K
Site 48
S409
G
K
A
F
Y
R
S
S
H
L
A
K
H
K
R
Site 49
T419
A
K
H
K
R
I
H
T
G
E
K
P
Y
T
C
Site 50
S436
C
G
K
A
F
N
Q
S
S
T
L
I
L
H
K
Site 51
S437
G
K
A
F
N
Q
S
S
T
L
I
L
H
K
R
Site 52
S521
G
K
A
F
N
Q
S
S
G
L
I
I
H
R
S
Site 53
S528
S
G
L
I
I
H
R
S
I
H
S
E
Q
K
L
Site 54
S548
C
G
K
A
F
T
R
S
T
A
L
N
E
H
K
Site 55
T549
G
K
A
F
T
R
S
T
A
L
N
E
H
K
K
Site 56
Y564
I
H
S
G
E
K
P
Y
K
C
K
E
C
G
K
Site 57
S576
C
G
K
A
Y
N
L
S
S
T
L
T
K
H
K
Site 58
S577
G
K
A
Y
N
L
S
S
T
L
T
K
H
K
R
Site 59
T580
Y
N
L
S
S
T
L
T
K
H
K
R
I
H
T
Site 60
T587
T
K
H
K
R
I
H
T
G
E
K
P
F
T
C
Site 61
T593
H
T
G
E
K
P
F
T
C
E
E
C
G
K
A
Site 62
S604
C
G
K
A
F
N
W
S
S
S
L
T
K
H
K
Site 63
S605
G
K
A
F
N
W
S
S
S
L
T
K
H
K
I
Site 64
S606
K
A
F
N
W
S
S
S
L
T
K
H
K
I
I
Site 65
T608
F
N
W
S
S
S
L
T
K
H
K
I
I
H
T
Site 66
S633
G
K
A
F
N
R
P
S
T
L
T
V
H
K
R
Site 67
T634
K
A
F
N
R
P
S
T
L
T
V
H
K
R
I
Site 68
T636
F
N
R
P
S
T
L
T
V
H
K
R
I
H
T
Site 69
T643
T
V
H
K
R
I
H
T
G
K
E
H
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation