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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC56
Full Name:
Leucine-rich repeat-containing protein 56
Alias:
Type:
Mass (Da):
58733
Number AA:
542
UniProt ID:
Q8IYG6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
D
L
G
W
D
R
S
R
G
P
R
R
S
T
Site 2
S14
R
S
R
G
P
R
R
S
T
S
S
V
R
V
R
Site 3
T15
S
R
G
P
R
R
S
T
S
S
V
R
V
R
E
Site 4
S16
R
G
P
R
R
S
T
S
S
V
R
V
R
E
L
Site 5
S17
G
P
R
R
S
T
S
S
V
R
V
R
E
L
S
Site 6
S24
S
V
R
V
R
E
L
S
W
Q
G
L
H
N
P
Site 7
S35
L
H
N
P
C
P
Q
S
K
G
P
G
S
Q
R
Site 8
S40
P
Q
S
K
G
P
G
S
Q
R
D
R
L
G
E
Site 9
Y53
G
E
Q
L
V
E
E
Y
L
S
P
A
R
L
Q
Site 10
S55
Q
L
V
E
E
Y
L
S
P
A
R
L
Q
A
L
Site 11
T80
T
L
E
M
C
V
D
T
R
E
G
S
L
G
N
Site 12
S84
C
V
D
T
R
E
G
S
L
G
N
F
G
V
H
Site 13
S103
D
Q
L
K
L
N
G
S
H
L
G
S
L
R
D
Site 14
S107
L
N
G
S
H
L
G
S
L
R
D
L
G
T
S
Site 15
T113
G
S
L
R
D
L
G
T
S
L
G
H
L
Q
V
Site 16
Y144
L
P
A
L
K
E
L
Y
A
S
Y
N
N
I
S
Site 17
S146
A
L
K
E
L
Y
A
S
Y
N
N
I
S
D
L
Site 18
Y147
L
K
E
L
Y
A
S
Y
N
N
I
S
D
L
S
Site 19
S154
Y
N
N
I
S
D
L
S
P
L
C
L
L
E
Q
Site 20
Y180
E
D
L
G
Q
V
R
Y
L
Q
L
C
P
R
L
Site 21
Y213
T
N
K
V
P
R
G
Y
N
Y
R
A
E
V
R
Site 22
T237
D
E
V
P
A
A
H
T
G
P
P
A
P
P
R
Site 23
S246
P
P
A
P
P
R
L
S
Q
D
W
L
A
V
K
Site 24
S281
R
R
L
D
P
E
L
S
L
P
E
T
Q
S
R
Site 25
T285
P
E
L
S
L
P
E
T
Q
S
R
A
S
R
P
Site 26
S287
L
S
L
P
E
T
Q
S
R
A
S
R
P
W
P
Site 27
S290
P
E
T
Q
S
R
A
S
R
P
W
P
F
S
L
Site 28
S296
A
S
R
P
W
P
F
S
L
L
V
R
G
G
P
Site 29
S310
P
L
P
E
G
L
L
S
E
D
L
A
P
E
D
Site 30
S320
L
A
P
E
D
N
T
S
S
L
T
H
G
A
G
Site 31
S321
A
P
E
D
N
T
S
S
L
T
H
G
A
G
Q
Site 32
S365
R
P
G
D
P
A
A
S
T
S
T
P
E
P
D
Site 33
T366
P
G
D
P
A
A
S
T
S
T
P
E
P
D
P
Site 34
S367
G
D
P
A
A
S
T
S
T
P
E
P
D
P
A
Site 35
T368
D
P
A
A
S
T
S
T
P
E
P
D
P
A
D
Site 36
S377
E
P
D
P
A
D
S
S
D
F
L
A
L
A
G
Site 37
Y398
H
G
V
R
P
L
P
Y
R
H
P
E
S
Q
Q
Site 38
S403
L
P
Y
R
H
P
E
S
Q
Q
E
G
A
V
A
Site 39
T429
V
H
Q
A
E
P
K
T
P
S
S
P
P
S
L
Site 40
S431
Q
A
E
P
K
T
P
S
S
P
P
S
L
A
S
Site 41
S432
A
E
P
K
T
P
S
S
P
P
S
L
A
S
E
Site 42
S435
K
T
P
S
S
P
P
S
L
A
S
E
P
S
G
Site 43
S438
S
S
P
P
S
L
A
S
E
P
S
G
T
S
S
Site 44
S441
P
S
L
A
S
E
P
S
G
T
S
S
Q
H
L
Site 45
T443
L
A
S
E
P
S
G
T
S
S
Q
H
L
V
P
Site 46
S445
S
E
P
S
G
T
S
S
Q
H
L
V
P
S
P
Site 47
S451
S
S
Q
H
L
V
P
S
P
P
K
H
P
R
P
Site 48
S461
K
H
P
R
P
R
D
S
G
S
S
S
P
R
W
Site 49
S463
P
R
P
R
D
S
G
S
S
S
P
R
W
S
T
Site 50
S464
R
P
R
D
S
G
S
S
S
P
R
W
S
T
D
Site 51
S465
P
R
D
S
G
S
S
S
P
R
W
S
T
D
L
Site 52
S469
G
S
S
S
P
R
W
S
T
D
L
Q
S
R
G
Site 53
T470
S
S
S
P
R
W
S
T
D
L
Q
S
R
G
R
Site 54
S474
R
W
S
T
D
L
Q
S
R
G
R
R
L
R
V
Site 55
S484
R
R
L
R
V
L
G
S
W
G
P
G
L
G
D
Site 56
S506
L
R
A
L
E
V
A
S
R
L
S
P
R
A
Q
Site 57
S509
L
E
V
A
S
R
L
S
P
R
A
Q
G
C
P
Site 58
S535
P
P
R
A
A
E
L
S
H
P
S
P
V
P
T
Site 59
S538
A
A
E
L
S
H
P
S
P
V
P
T
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation