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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EXOC8
Full Name:
Exocyst complex component 8
Alias:
Exocyst complex 84 kDa subunit
Type:
Vesicle protein
Mass (Da):
81799
Number AA:
725
UniProt ID:
Q8IYI6
International Prot ID:
IPI00028264
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030426
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006887
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
M
A
M
S
D
S
G
A
S
R
L
R
R
Site 2
S19
R
L
R
R
Q
L
E
S
G
G
F
E
A
R
L
Site 3
Y27
G
G
F
E
A
R
L
Y
V
K
Q
L
S
Q
Q
Site 4
S32
R
L
Y
V
K
Q
L
S
Q
Q
S
D
G
D
R
Site 5
Y64
Q
N
L
K
R
N
V
Y
Q
N
Y
R
Q
F
I
Site 6
T73
N
Y
R
Q
F
I
E
T
A
R
E
I
S
Y
L
Site 7
S78
I
E
T
A
R
E
I
S
Y
L
E
S
E
M
Y
Site 8
Y79
E
T
A
R
E
I
S
Y
L
E
S
E
M
Y
Q
Site 9
S82
R
E
I
S
Y
L
E
S
E
M
Y
Q
L
S
H
Site 10
Y85
S
Y
L
E
S
E
M
Y
Q
L
S
H
L
L
T
Site 11
S88
E
S
E
M
Y
Q
L
S
H
L
L
T
E
Q
K
Site 12
T92
Y
Q
L
S
H
L
L
T
E
Q
K
S
S
L
E
Site 13
S96
H
L
L
T
E
Q
K
S
S
L
E
S
I
P
L
Site 14
S97
L
L
T
E
Q
K
S
S
L
E
S
I
P
L
T
Site 15
S100
E
Q
K
S
S
L
E
S
I
P
L
T
L
L
P
Site 16
S141
R
G
Q
A
G
F
F
S
T
P
G
G
A
S
R
Site 17
T142
G
Q
A
G
F
F
S
T
P
G
G
A
S
R
D
Site 18
S147
F
S
T
P
G
G
A
S
R
D
G
S
G
P
G
Site 19
S151
G
G
A
S
R
D
G
S
G
P
G
E
E
G
K
Site 20
T163
E
G
K
Q
R
T
L
T
T
L
L
E
K
V
E
Site 21
T178
G
C
R
H
L
L
E
T
P
G
Q
Y
L
V
Y
Site 22
Y182
L
L
E
T
P
G
Q
Y
L
V
Y
N
G
D
L
Site 23
Y192
Y
N
G
D
L
V
E
Y
D
A
D
H
M
A
Q
Site 24
Y225
L
P
Q
R
R
G
M
Y
R
Y
N
A
L
Y
S
Site 25
Y227
Q
R
R
G
M
Y
R
Y
N
A
L
Y
S
L
D
Site 26
S259
K
L
L
M
F
P
E
S
R
I
F
Q
A
E
N
Site 27
T280
W
L
E
V
L
E
D
T
K
R
A
L
S
E
K
Site 28
S285
E
D
T
K
R
A
L
S
E
K
R
R
R
E
Q
Site 29
S333
E
E
E
K
V
D
L
S
M
E
W
I
Q
E
L
Site 30
Y366
L
L
D
K
L
N
H
Y
L
E
D
K
P
S
P
Site 31
S372
H
Y
L
E
D
K
P
S
P
P
P
V
K
E
L
Site 32
T391
E
E
R
V
R
Q
L
T
E
V
L
V
F
E
L
Site 33
S399
E
V
L
V
F
E
L
S
P
D
R
S
L
R
G
Site 34
S403
F
E
L
S
P
D
R
S
L
R
G
G
P
K
A
Site 35
T411
L
R
G
G
P
K
A
T
R
R
A
V
S
Q
L
Site 36
S416
K
A
T
R
R
A
V
S
Q
L
I
R
L
G
Q
Site 37
Y455
I
E
G
A
T
L
L
Y
I
H
K
L
C
H
V
Site 38
S505
G
M
F
V
D
A
F
S
K
Q
V
F
D
S
K
Site 39
S511
F
S
K
Q
V
F
D
S
K
E
S
L
S
T
A
Site 40
S514
Q
V
F
D
S
K
E
S
L
S
T
A
A
E
C
Site 41
S516
F
D
S
K
E
S
L
S
T
A
A
E
C
V
K
Site 42
T517
D
S
K
E
S
L
S
T
A
A
E
C
V
K
V
Site 43
S557
D
I
Q
G
A
L
H
S
Y
K
E
I
I
I
E
Site 44
T582
W
R
R
M
N
L
M
T
P
E
A
L
G
K
L
Site 45
S595
K
L
K
E
E
M
K
S
C
G
V
S
N
F
E
Site 46
Y660
V
A
V
Q
H
V
D
Y
S
L
R
C
E
Q
D
Site 47
S661
A
V
Q
H
V
D
Y
S
L
R
C
E
Q
D
P
Site 48
S711
L
Q
D
L
R
N
A
S
R
L
I
R
V
N
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation