PhosphoNET

           
Protein Info 
   
Short Name:  PM20D2
Full Name:  Peptidase M20 domain-containing protein 2
Alias:  Aminoacylase-1-like protein 2
Type: 
Mass (Da):  47776
Number AA:  436
UniProt ID:  Q8IYS1
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S42AERLGALSRAIWSQP
Site 2S47ALSRAIWSQPELAYE
Site 3Y53WSQPELAYEEHHAHR
Site 4T63HHAHRVLTHFFEREP
Site 5S74EREPPAASWAVQPHY
Site 6Y81SWAVQPHYQLPTAFR
Site 7T85QPHYQLPTAFRAEWE
Site 8S100PPEARAPSATPRPLH
Site 9T102EARAPSATPRPLHLG
Site 10Y197PSQENAAYLPDMAEH
Site 11T207DMAEHDVTVKYYGKA
Site 12Y210EHDVTVKYYGKASHS
Site 13S219GKASHSASYPWEGLN
Site 14Y220KASHSASYPWEGLNA
Site 15S267VKPNIIPSYSELIYY
Site 16Y268KPNIIPSYSELIYYF
Site 17Y273PSYSELIYYFRAPSM
Site 18Y274SYSELIYYFRAPSMK
Site 19Y314IKGGAHDYYNVLPNK
Site 20Y315KGGAHDYYNVLPNKS
Site 21T343IEFISEDTMLNGPSG
Site 22S387QYTEAAGSQEAQFYT
Site 23Y393GSQEAQFYTLRTAKA
Site 24T394SQEAQFYTLRTAKAL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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