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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KATNAL2
Full Name:
Katanin p60 ATPase-containing subunit A-like 2
Alias:
DKFZP667C165; katanin p60 atpase-containing subunit a-like 2; katanin p60 subunit a-like 2; katl2; katnal2; MGC33211; p60 katanin-like 2
Type:
EC 3.6.4.3; Hydrolase
Mass (Da):
61250
Number AA:
UniProt ID:
Q8IYT4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008568
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y75
L
E
T
I
L
M
E
Y
E
S
Y
Y
F
V
K
Site 2
Y78
I
L
M
E
Y
E
S
Y
Y
F
V
K
F
Q
K
Site 3
Y79
L
M
E
Y
E
S
Y
Y
F
V
K
F
Q
K
Y
Site 4
Y86
Y
F
V
K
F
Q
K
Y
P
K
I
V
K
K
S
Site 5
S94
P
K
I
V
K
K
S
S
D
T
A
E
N
N
L
Site 6
T109
P
Q
R
S
R
G
K
T
R
R
M
M
N
D
S
Site 7
S130
I
N
Q
Q
R
P
R
S
K
T
T
A
G
K
T
Site 8
T132
Q
Q
R
P
R
S
K
T
T
A
G
K
T
G
D
Site 9
T137
S
K
T
T
A
G
K
T
G
D
T
K
S
L
N
Site 10
S142
G
K
T
G
D
T
K
S
L
N
K
E
H
P
N
Site 11
S160
V
D
N
T
R
L
E
S
A
N
F
G
L
H
I
Site 12
S168
A
N
F
G
L
H
I
S
R
I
R
K
D
S
G
Site 13
S174
I
S
R
I
R
K
D
S
G
E
E
N
A
H
P
Site 14
T208
T
S
E
L
A
L
N
T
F
D
H
N
P
D
P
Site 15
S216
F
D
H
N
P
D
P
S
E
R
L
L
K
P
L
Site 16
S241
R
E
L
A
A
V
V
S
R
D
I
Y
L
H
N
Site 17
Y245
A
V
V
S
R
D
I
Y
L
H
N
P
N
I
K
Site 18
T281
I
R
Y
P
Q
L
F
T
G
I
L
S
P
W
K
Site 19
Y293
P
W
K
G
L
L
L
Y
G
P
P
G
T
G
K
Site 20
S325
I
S
A
S
T
I
V
S
K
W
R
G
D
S
E
Site 21
S331
V
S
K
W
R
G
D
S
E
K
L
V
R
V
L
Site 22
S357
I
F
L
D
E
L
E
S
V
M
S
Q
R
G
T
Site 23
S360
D
E
L
E
S
V
M
S
Q
R
G
T
A
S
G
Site 24
T364
S
V
M
S
Q
R
G
T
A
S
G
G
E
H
E
Site 25
S373
S
G
G
E
H
E
G
S
L
R
M
K
T
E
L
Site 26
T378
E
G
S
L
R
M
K
T
E
L
L
V
Q
M
D
Site 27
S424
R
I
L
V
D
L
P
S
R
E
A
R
Q
A
M
Site 28
Y433
E
A
R
Q
A
M
I
Y
H
W
L
P
P
V
S
Site 29
S440
Y
H
W
L
P
P
V
S
K
S
R
A
L
E
L
Site 30
S442
W
L
P
P
V
S
K
S
R
A
L
E
L
H
T
Site 31
S454
L
H
T
E
L
E
Y
S
V
L
S
Q
E
T
E
Site 32
S457
E
L
E
Y
S
V
L
S
Q
E
T
E
G
Y
S
Site 33
Y463
L
S
Q
E
T
E
G
Y
S
G
S
D
I
K
L
Site 34
S466
E
T
E
G
Y
S
G
S
D
I
K
L
V
C
R
Site 35
S492
D
A
L
E
N
H
Q
S
E
S
S
D
L
P
R
Site 36
S495
E
N
H
Q
S
E
S
S
D
L
P
R
I
Q
L
Site 37
T515
A
D
F
L
D
V
L
T
H
T
K
P
S
A
K
Site 38
S529
K
N
L
A
Q
R
Y
S
D
W
Q
R
E
F
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation