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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFHA1
Full Name:
EF-hand domain-containing family member A1
Alias:
EF-hand domain family, member A1
Type:
Mass (Da):
49666
Number AA:
434
UniProt ID:
Q8IYU8
International Prot ID:
IPI00640276
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
L
R
R
G
L
A
V
S
R
Q
A
V
R
S
P
Site 2
S31
V
S
R
Q
A
V
R
S
P
G
P
L
A
A
A
Site 3
S54
A
G
A
A
W
H
H
S
R
V
S
V
A
A
R
Site 4
S57
A
W
H
H
S
R
V
S
V
A
A
R
D
G
S
Site 5
S64
S
V
A
A
R
D
G
S
F
T
V
S
A
Q
K
Site 6
T66
A
A
R
D
G
S
F
T
V
S
A
Q
K
N
V
Site 7
S68
R
D
G
S
F
T
V
S
A
Q
K
N
V
E
H
Site 8
Y79
N
V
E
H
G
I
I
Y
I
G
K
P
S
L
R
Site 9
S94
K
Q
R
F
M
Q
F
S
S
L
E
H
E
G
E
Site 10
S95
Q
R
F
M
Q
F
S
S
L
E
H
E
G
E
Y
Site 11
Y103
L
E
H
E
G
E
Y
Y
M
T
P
R
D
F
L
Site 12
T105
H
E
G
E
Y
Y
M
T
P
R
D
F
L
F
S
Site 13
T122
F
E
Q
M
E
R
K
T
S
V
K
K
L
T
K
Site 14
S123
E
Q
M
E
R
K
T
S
V
K
K
L
T
K
K
Site 15
T135
T
K
K
D
I
E
D
T
L
S
G
I
Q
T
A
Site 16
S137
K
D
I
E
D
T
L
S
G
I
Q
T
A
G
C
Site 17
T147
Q
T
A
G
C
G
S
T
F
F
R
D
L
G
D
Site 18
T186
V
A
F
K
M
L
D
T
D
G
N
E
M
I
E
Site 19
S205
F
K
L
Q
K
I
I
S
K
Q
D
D
L
M
T
Site 20
T212
S
K
Q
D
D
L
M
T
V
K
T
N
E
T
G
Site 21
T233
K
E
P
E
I
N
T
T
L
Q
M
R
F
F
G
Site 22
Y249
R
G
Q
R
K
L
H
Y
K
E
F
R
R
F
M
Site 23
T261
R
F
M
E
N
L
Q
T
E
I
Q
E
M
E
F
Site 24
S276
L
Q
F
S
K
G
L
S
F
M
R
K
E
D
F
Site 25
Y299
N
T
E
N
K
D
I
Y
W
K
N
V
R
E
K
Site 26
S308
K
N
V
R
E
K
L
S
A
G
E
S
I
S
L
Site 27
S312
E
K
L
S
A
G
E
S
I
S
L
D
E
F
K
Site 28
S314
L
S
A
G
E
S
I
S
L
D
E
F
K
S
F
Site 29
S383
L
D
G
D
E
C
L
S
H
E
E
F
L
G
V
Site 30
Y410
Q
H
Q
S
I
Q
E
Y
W
K
C
V
K
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation