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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC116
Full Name:
Coiled-coil domain-containing protein 116
Alias:
Type:
Mass (Da):
56940
Number AA:
515
UniProt ID:
Q8IYX3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
R
C
R
H
H
S
G
Y
L
A
D
D
E
Site 2
Y10
R
C
R
H
H
S
G
Y
L
A
D
D
E
A
S
Site 3
S17
Y
L
A
D
D
E
A
S
H
S
M
C
S
A
R
Site 4
S19
A
D
D
E
A
S
H
S
M
C
S
A
R
V
Q
Site 5
S22
E
A
S
H
S
M
C
S
A
R
V
Q
L
P
K
Site 6
S50
G
R
V
P
H
P
P
S
T
C
G
S
S
A
L
Site 7
T51
R
V
P
H
P
P
S
T
C
G
S
S
A
L
Q
Site 8
S54
H
P
P
S
T
C
G
S
S
A
L
Q
G
Q
R
Site 9
T78
G
H
F
L
D
F
L
T
E
S
Q
V
L
D
S
Site 10
S85
T
E
S
Q
V
L
D
S
L
E
T
V
V
E
K
Site 11
S119
Q
D
P
V
E
V
P
S
G
G
R
R
A
H
A
Site 12
S129
R
R
A
H
A
R
P
S
L
S
T
V
H
R
H
Site 13
S131
A
H
A
R
P
S
L
S
T
V
H
R
H
R
V
Site 14
T132
H
A
R
P
S
L
S
T
V
H
R
H
R
V
R
Site 15
T141
H
R
H
R
V
R
P
T
L
C
T
G
H
P
N
Site 16
T144
R
V
R
P
T
L
C
T
G
H
P
N
N
Y
P
Site 17
Y150
C
T
G
H
P
N
N
Y
P
S
S
S
S
S
M
Site 18
S152
G
H
P
N
N
Y
P
S
S
S
S
S
M
S
N
Site 19
S153
H
P
N
N
Y
P
S
S
S
S
S
M
S
N
C
Site 20
S154
P
N
N
Y
P
S
S
S
S
S
M
S
N
C
H
Site 21
S155
N
N
Y
P
S
S
S
S
S
M
S
N
C
H
S
Site 22
S156
N
Y
P
S
S
S
S
S
M
S
N
C
H
S
S
Site 23
S158
P
S
S
S
S
S
M
S
N
C
H
S
S
L
M
Site 24
S171
L
M
A
G
C
L
G
S
H
S
R
D
S
D
L
Site 25
S173
A
G
C
L
G
S
H
S
R
D
S
D
L
G
A
Site 26
S176
L
G
S
H
S
R
D
S
D
L
G
A
Q
G
S
Site 27
S183
S
D
L
G
A
Q
G
S
L
P
P
V
R
D
K
Site 28
S211
E
R
E
G
K
G
L
S
Q
S
C
S
Q
R
D
Site 29
S213
E
G
K
G
L
S
Q
S
C
S
Q
R
D
S
L
Site 30
S215
K
G
L
S
Q
S
C
S
Q
R
D
S
L
L
W
Site 31
S219
Q
S
C
S
Q
R
D
S
L
L
W
D
S
L
G
Site 32
S224
R
D
S
L
L
W
D
S
L
G
S
Q
T
S
F
Site 33
S227
L
L
W
D
S
L
G
S
Q
T
S
F
Q
W
T
Site 34
S230
D
S
L
G
S
Q
T
S
F
Q
W
T
Q
E
Q
Site 35
T234
S
Q
T
S
F
Q
W
T
Q
E
Q
P
L
S
W
Site 36
S240
W
T
Q
E
Q
P
L
S
W
F
S
G
L
L
G
Site 37
S243
E
Q
P
L
S
W
F
S
G
L
L
G
S
S
S
Site 38
S250
S
G
L
L
G
S
S
S
G
V
P
E
A
S
E
Site 39
S256
S
S
G
V
P
E
A
S
E
P
R
P
G
E
Q
Site 40
S278
E
F
N
K
E
I
K
S
L
L
S
Q
L
E
S
Site 41
S281
K
E
I
K
S
L
L
S
Q
L
E
S
L
D
L
Site 42
Y291
E
S
L
D
L
P
G
Y
C
P
L
R
E
P
H
Site 43
T300
P
L
R
E
P
H
R
T
L
N
F
L
A
D
H
Site 44
S318
P
A
L
Q
S
V
V
S
Q
A
V
D
K
L
R
Site 45
T338
D
G
R
P
L
F
P
T
S
L
E
P
T
S
D
Site 46
S339
G
R
P
L
F
P
T
S
L
E
P
T
S
D
L
Site 47
T343
F
P
T
S
L
E
P
T
S
D
L
P
P
L
G
Site 48
S344
P
T
S
L
E
P
T
S
D
L
P
P
L
G
S
Site 49
S351
S
D
L
P
P
L
G
S
E
P
A
K
P
T
N
Site 50
Y363
P
T
N
G
G
Q
P
Y
A
S
P
R
P
T
V
Site 51
S365
N
G
G
Q
P
Y
A
S
P
R
P
T
V
S
S
Site 52
T369
P
Y
A
S
P
R
P
T
V
S
S
P
K
M
L
Site 53
S371
A
S
P
R
P
T
V
S
S
P
K
M
L
Q
R
Site 54
S372
S
P
R
P
T
V
S
S
P
K
M
L
Q
R
K
Site 55
S386
K
R
K
D
R
G
G
S
P
S
M
S
S
A
Q
Site 56
S388
K
D
R
G
G
S
P
S
M
S
S
A
Q
V
A
Site 57
S390
R
G
G
S
P
S
M
S
S
A
Q
V
A
T
R
Site 58
S391
G
G
S
P
S
M
S
S
A
Q
V
A
T
R
F
Site 59
S402
A
T
R
F
K
L
K
S
P
C
S
S
S
R
F
Site 60
S405
F
K
L
K
S
P
C
S
S
S
R
F
T
K
K
Site 61
S406
K
L
K
S
P
C
S
S
S
R
F
T
K
K
K
Site 62
S407
L
K
S
P
C
S
S
S
R
F
T
K
K
K
P
Site 63
T410
P
C
S
S
S
R
F
T
K
K
K
P
L
P
S
Site 64
S417
T
K
K
K
P
L
P
S
I
S
S
K
S
S
M
Site 65
S419
K
K
P
L
P
S
I
S
S
K
S
S
M
S
H
Site 66
S420
K
P
L
P
S
I
S
S
K
S
S
M
S
H
F
Site 67
S422
L
P
S
I
S
S
K
S
S
M
S
H
F
S
N
Site 68
S423
P
S
I
S
S
K
S
S
M
S
H
F
S
N
R
Site 69
S425
I
S
S
K
S
S
M
S
H
F
S
N
R
L
Y
Site 70
S428
K
S
S
M
S
H
F
S
N
R
L
Y
E
E
L
Site 71
Y432
S
H
F
S
N
R
L
Y
E
E
L
A
D
F
L
Site 72
Y451
A
S
L
V
I
R
K
Y
E
F
E
K
D
L
S
Site 73
S458
Y
E
F
E
K
D
L
S
K
Q
L
G
F
F
S
Site 74
S476
T
H
V
L
R
D
L
S
L
G
L
K
K
V
K
Site 75
S490
K
G
S
R
I
H
L
S
S
E
T
H
R
S
C
Site 76
S491
G
S
R
I
H
L
S
S
E
T
H
R
S
C
L
Site 77
T493
R
I
H
L
S
S
E
T
H
R
S
C
L
L
R
Site 78
S496
L
S
S
E
T
H
R
S
C
L
L
R
K
L
E
Site 79
S505
L
L
R
K
L
E
E
S
K
R
A
A
A
V
S
Site 80
S512
S
K
R
A
A
A
V
S
L
E
A
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation