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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CEP57R
Full Name:
Cep57-related protein
Alias:
Centrosomal protein 57kDa-like protein 1;Centrosomal protein of 57 kDa-related protein;Cep57-related protein
Type:
Mass (Da):
53649
Number AA:
460
UniProt ID:
Q8IYX8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
D
S
E
L
M
H
S
I
V
G
S
Y
H
K
Site 2
S12
L
M
H
S
I
V
G
S
Y
H
K
P
P
E
R
Site 3
Y13
M
H
S
I
V
G
S
Y
H
K
P
P
E
R
V
Site 4
S24
P
E
R
V
F
V
P
S
F
T
Q
N
E
P
S
Site 5
S43
P
A
N
L
E
V
T
S
P
K
I
L
H
S
P
Site 6
S49
T
S
P
K
I
L
H
S
P
N
S
Q
A
L
I
Site 7
T74
H
R
L
E
L
E
R
T
Q
A
E
D
N
L
N
Site 8
Y90
L
S
R
E
A
A
Q
Y
K
K
A
L
E
N
E
Site 9
S116
I
K
Q
K
K
D
I
S
I
Q
L
S
S
A
Q
Site 10
S120
K
D
I
S
I
Q
L
S
S
A
Q
S
R
C
T
Site 11
S124
I
Q
L
S
S
A
Q
S
R
C
T
L
L
E
K
Site 12
T127
S
S
A
Q
S
R
C
T
L
L
E
K
Q
L
E
Site 13
T136
L
E
K
Q
L
E
Y
T
K
R
M
V
L
N
V
Site 14
Y169
E
Q
D
Q
M
K
L
Y
A
K
L
E
K
L
D
Site 15
T186
E
K
E
C
F
R
L
T
T
T
Q
K
T
A
E
Site 16
T187
K
E
C
F
R
L
T
T
T
Q
K
T
A
E
D
Site 17
S218
K
L
F
Q
D
K
A
S
E
L
Q
T
G
L
E
Site 18
T222
D
K
A
S
E
L
Q
T
G
L
E
I
S
K
I
Site 19
S232
E
I
S
K
I
I
M
S
S
V
S
N
L
K
H
Site 20
S233
I
S
K
I
I
M
S
S
V
S
N
L
K
H
S
Site 21
S235
K
I
I
M
S
S
V
S
N
L
K
H
S
K
E
Site 22
S240
S
V
S
N
L
K
H
S
K
E
K
K
K
S
S
Site 23
S246
H
S
K
E
K
K
K
S
S
K
K
T
K
C
I
Site 24
S247
S
K
E
K
K
K
S
S
K
K
T
K
C
I
K
Site 25
T250
K
K
K
S
S
K
K
T
K
C
I
K
R
R
P
Site 26
S300
T
R
C
L
P
K
P
S
R
T
T
S
W
C
K
Site 27
T303
L
P
K
P
S
R
T
T
S
W
C
K
A
I
P
Site 28
S304
P
K
P
S
R
T
T
S
W
C
K
A
I
P
P
Site 29
S313
C
K
A
I
P
P
D
S
E
K
S
I
S
I
C
Site 30
S316
I
P
P
D
S
E
K
S
I
S
I
C
D
N
L
Site 31
S318
P
D
S
E
K
S
I
S
I
C
D
N
L
S
E
Site 32
S338
Q
D
E
L
D
Q
M
S
M
E
H
Q
E
L
L
Site 33
T351
L
L
K
Q
M
K
E
T
E
S
H
S
V
C
D
Site 34
S355
M
K
E
T
E
S
H
S
V
C
D
D
I
E
C
Site 35
S379
E
I
K
G
E
Q
I
S
K
L
K
K
H
Q
D
Site 36
S387
K
L
K
K
H
Q
D
S
V
C
K
L
Q
Q
K
Site 37
S398
L
Q
Q
K
V
Q
N
S
K
M
S
E
A
S
G
Site 38
S401
K
V
Q
N
S
K
M
S
E
A
S
G
I
Q
Q
Site 39
S411
S
G
I
Q
Q
E
D
S
Y
P
K
G
S
K
N
Site 40
Y412
G
I
Q
Q
E
D
S
Y
P
K
G
S
K
N
I
Site 41
S416
E
D
S
Y
P
K
G
S
K
N
I
K
N
S
P
Site 42
S422
G
S
K
N
I
K
N
S
P
R
K
C
L
T
D
Site 43
T428
N
S
P
R
K
C
L
T
D
T
N
L
F
Q
K
Site 44
T430
P
R
K
C
L
T
D
T
N
L
F
Q
K
N
S
Site 45
S437
T
N
L
F
Q
K
N
S
S
F
H
P
I
R
V
Site 46
S438
N
L
F
Q
K
N
S
S
F
H
P
I
R
V
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation