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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC34
Full Name:
Leucine-rich repeat-containing protein 34
Alias:
LRC34
Type:
Mass (Da):
46414
Number AA:
419
UniProt ID:
Q8IZ02
International Prot ID:
IPI00217826
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
A
A
R
A
P
A
R
S
P
A
W
A
S
T
Q
Site 2
S19
A
R
S
P
A
W
A
S
T
Q
A
S
T
P
G
Site 3
T20
R
S
P
A
W
A
S
T
Q
A
S
T
P
G
A
Site 4
S35
A
L
A
V
Q
R
E
S
P
E
S
G
L
Q
K
Site 5
S38
V
Q
R
E
S
P
E
S
G
L
Q
K
H
Y
S
Site 6
S45
S
G
L
Q
K
H
Y
S
N
L
C
M
E
K
S
Site 7
Y142
Q
K
Q
L
N
L
I
Y
L
N
L
M
F
N
D
Site 8
T167
K
V
L
H
K
N
R
T
L
K
Y
L
R
M
T
Site 9
Y170
H
K
N
R
T
L
K
Y
L
R
M
T
G
N
K
Site 10
T174
T
L
K
Y
L
R
M
T
G
N
K
I
E
N
K
Site 11
T210
D
C
D
L
E
E
S
T
V
H
V
G
R
M
L
Site 12
Y246
Q
Q
L
C
D
A
L
Y
L
N
S
S
L
R
Y
Site 13
S250
D
A
L
Y
L
N
S
S
L
R
Y
L
D
V
S
Site 14
Y253
Y
L
N
S
S
L
R
Y
L
D
V
S
C
N
K
Site 15
S257
S
L
R
Y
L
D
V
S
C
N
K
I
T
H
D
Site 16
T262
D
V
S
C
N
K
I
T
H
D
G
M
V
Y
L
Site 17
Y268
I
T
H
D
G
M
V
Y
L
A
D
V
L
K
S
Site 18
S298
N
A
G
A
N
Y
L
S
E
T
L
T
S
H
N
Site 19
T302
N
Y
L
S
E
T
L
T
S
H
N
R
S
L
K
Site 20
S303
Y
L
S
E
T
L
T
S
H
N
R
S
L
K
A
Site 21
S307
T
L
T
S
H
N
R
S
L
K
A
L
S
V
V
Site 22
S312
N
R
S
L
K
A
L
S
V
V
S
N
N
I
E
Site 23
S327
G
E
G
L
V
A
L
S
Q
S
M
K
T
N
L
Site 24
T332
A
L
S
Q
S
M
K
T
N
L
T
F
S
H
I
Site 25
T350
G
N
K
F
D
E
A
T
C
I
T
Y
S
D
L
Site 26
T368
G
C
L
K
P
D
N
T
D
V
E
P
F
V
V
Site 27
Y392
S
N
G
L
K
K
H
Y
Y
W
T
S
T
Y
G
Site 28
Y393
N
G
L
K
K
H
Y
Y
W
T
S
T
Y
G
E
Site 29
Y398
H
Y
Y
W
T
S
T
Y
G
E
S
Y
D
H
S
Site 30
S401
W
T
S
T
Y
G
E
S
Y
D
H
S
S
N
A
Site 31
Y402
T
S
T
Y
G
E
S
Y
D
H
S
S
N
A
G
Site 32
S405
Y
G
E
S
Y
D
H
S
S
N
A
G
F
A
L
Site 33
S406
G
E
S
Y
D
H
S
S
N
A
G
F
A
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation