PhosphoNET

           
Protein Info 
   
Short Name:  GPR135
Full Name:  Probable G-protein coupled receptor 135
Alias:  G protein-coupled receptor 135; Gp135; Gpr135; Humnpiiy20
Type: 
Mass (Da):  51736
Number AA:  494
UniProt ID:  Q8IZ08
International Prot ID:  IPI00478110
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021  GO:0005886   Uniprot OncoNet
Molecular Function:  GO:0004930     PhosphoSite+ KinaseNET
Biological Process:  GO:0007186     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S12QPPRPPASMALLGSQ
Site 2S18ASMALLGSQHSGAPS
Site 3S21ALLGSQHSGAPSAAG
Site 4S25SQHSGAPSAAGPPGG
Site 5S56TAALGNLSDASGGGT
Site 6T63SDASGGGTAAAPGGG
Site 7S75GGGGLGGSGAAREAG
Site 8S258RELAAAQSFHGCLYR
Site 9Y264QSFHGCLYRTSPDPA
Site 10S267HGCLYRTSPDPAQLG
Site 11Y317RVRPVNTYARVLRFF
Site 12S395AIRNPNISMLLGRNR
Site 13T408NREEGYRTRNVDAFL
Site 14S417NVDAFLPSQGPGLQA
Site 15S426GPGLQARSRSRLRNR
Site 16S428GLQARSRSRLRNRYA
Site 17Y434RSRLRNRYANRLGAC
Site 18S445LGACNRMSSSNPASG
Site 19S446GACNRMSSSNPASGV
Site 20S447ACNRMSSSNPASGVA
Site 21S451MSSSNPASGVAGDVA
Site 22T479EGPPEPVTAVTKQPK
Site 23T482PEPVTAVTKQPKSEA
Site 24S487AVTKQPKSEAGDTSL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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