PhosphoNET

           
Protein Info 
   
Short Name:  PRR22
Full Name:  Proline-rich protein 22
Alias: 
Type: 
Mass (Da):  43802
Number AA:  420
UniProt ID:  Q8IZ63
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y20PARAPKQYLCRPPKG
Site 2S37NGKVLVASPKQAPRL
Site 3S49PRLGLGPSGSSCSQG
Site 4S51LGLGPSGSSCSQGTR
Site 5S52GLGPSGSSCSQGTRL
Site 6S54GPSGSSCSQGTRLPP
Site 7T62QGTRLPPTGFQMAPC
Site 8T84IYRIEWTTPDLGQSA
Site 9Y93DLGQSALYKLAASSG
Site 10S111GVPSAPGSYLLEPQP
Site 11Y119YLLEPQPYLKAPGLP
Site 12Y128KAPGLPPYPHYQQAP
Site 13Y131GLPPYPHYQQAPGGP
Site 14Y144GPQFLLPYFPPEGPG
Site 15T203ITLPAEPTLPPDAYS
Site 16Y209PTLPPDAYSHLQGHL
Site 17S210TLPPDAYSHLQGHLG
Site 18S235PVKELQGSGARPGVP
Site 19Y244ARPGVPLYPPGLSEL
Site 20T272GKAKAPKTARALALP
Site 21T303GASEPEGTLCEVPGP
Site 22S315PGPALPDSSGGNSAD
Site 23S320PDSSGGNSADDIRSL
Site 24S326NSADDIRSLCLPEEL
Site 25S335CLPEELLSFDYSVPE
Site 26Y338EELLSFDYSVPEILD
Site 27T372PHPGPPATNTPAPIL
Site 28T374PGPPATNTPAPILSG
Site 29S380NTPAPILSGKRKAST
Site 30S386LSGKRKASTAKKGKP
Site 31T387SGKRKASTAKKGKPG
Site 32S405RQPAGPASATPPGPR
Site 33T407PAGPASATPPGPRED
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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